to the disease - risk ( D - variantscontributeto the disease - risk ( D - variants

to disease resistancecontributingto disease resistance

to the disease traitpotentially contributingto the disease trait

risk to diseasecontributerisk to disease

rare diseases and complex traitscausingrare diseases and complex traits

disease “ mutationscausedisease “ mutations

disease progressioninfluencingdisease progression

to a specific diseasecontributingto a specific disease

disease courseinfluencingdisease course

to genetic diseasecontributeto genetic disease

to disease liabilitycontributingto disease liability

Mendelian diseasecauseMendelian disease

to rare disease phenotypes and Mendelian conditionscontributingto rare disease phenotypes and Mendelian conditions

to misregulated gene expression and human diseaseleadto misregulated gene expression and human disease

to the development of common diseases like CDcontributeto the development of common diseases like CD

to a loss of TREM2 function impair microglia signalingleadingto a loss of TREM2 function impair microglia signaling

infantile - onset diseasecausinginfantile - onset disease

the likelihood of developing diseaseinfluencethe likelihood of developing disease

or modify disease in ALScauseor modify disease in ALS

disease or affect traitscausedisease or affect traits

in isolation or in combination ... to a particular trait or diseasecould leadin isolation or in combination ... to a particular trait or disease

disease or increasing susceptibility to diseaseare causingdisease or increasing susceptibility to disease

to breast cancer risk in our populationcontributingto breast cancer risk in our population

to complex traits ( 14contributingto complex traits ( 14

phenotypic variationcausingphenotypic variation

or modify the phenotypescauseor modify the phenotypes

to adaptive phenotypescontributeto adaptive phenotypes

myopathic phenotypesinfluencingmyopathic phenotypes

aberrant splicing in tumorsmay causeaberrant splicing in tumors

to a disease in the future ... with a certain probabilitymight leadto a disease in the future ... with a certain probability

to a certain tendency to get this diseasecontributeto a certain tendency to get this disease

from genome - wide association studies ( GWASdiscoveredfrom genome - wide association studies ( GWAS

to loss of function of PLPBPleadingto loss of function of PLPBP

to a complete loss of functionleadto a complete loss of function

in loss of function of DSC2resultingin loss of function of DSC2

to breast cancer risk in Southern Finlandcontributingto breast cancer risk in Southern Finland

to help them apply across different scientific fields or different career stages [ 1designedto help them apply across different scientific fields or different career stages [ 1

in whole genome sequencing surveys and possible diagnostic analysis of disease gene subsetsdiscoveredin whole genome sequencing surveys and possible diagnostic analysis of disease gene subsets

in sequencing studiesdiscoveredin sequencing studies

other approaches as wellto preventother approaches as well