mutations in the cystic fibrosis transmembrane conductance regulator ( CFTR ) gene ultimately resulting in impaired bacterial clearance in the airways and lung destruction(passive) caused byciliated epithelial cells
from kidney infectioncan resultfrom kidney infection
from kidney infection , bladder infection , an infection in the urethra , or immune disorderscan resultfrom kidney infection , bladder infection , an infection in the urethra , or immune disorders
alsocontributesalso
in a systemic infectioncould resultin a systemic infection
to infectionleadsto infection
mRNA stability(passive) caused bymRNA stability
in epithelial cell proliferation and induction of local inflammatory pathwaysresultsin epithelial cell proliferation and induction of local inflammatory pathways
to eradication failure and persistent throat carriage(74may contributeto eradication failure and persistent throat carriage(74
to cancer metastasisleadsto cancer metastasis
to massive polycystic enlargement of the excretory kidneyleadingto massive polycystic enlargement of the excretory kidney
to 36 % of the total fibroblasts pool through EMTcontributedto 36 % of the total fibroblasts pool through EMT
an increase in sodium excretion with little or no effect on potassium excretioncausingan increase in sodium excretion with little or no effect on potassium excretion
to reduced ATP and heme formationleadingto reduced ATP and heme formation
to cysticleadingto cystic
to proteinuria 3leadsto proteinuria 3
sebum and keratin to accumulate and block hair folliclescausessebum and keratin to accumulate and block hair follicles
to adult podocyte regenerationcontributeto adult podocyte regeneration
in decreased microcomedone formationresultingin decreased microcomedone formation
extrusion of the comedonescausingextrusion of the comedones
extrusion of the after comedonescausingextrusion of the after comedones
extrusion of the skincausingextrusion of the skin
extrusion of the blackheads ( comedonescausingextrusion of the blackheads ( comedones
to adult podocyte regeneration in experimental focal segmental glomerulosclerosiscontributeto adult podocyte regeneration in experimental focal segmental glomerulosclerosis
in diffuse infiltration andleadingin diffuse infiltration and
extrusion of the micro comedonescausingextrusion of the micro comedones
to tumor genesis and developmentleadingto tumor genesis and development
in decreased microcomedone translocationcausingin decreased microcomedone translocation
to excessive mucous secretionleadingto excessive mucous secretion
to the formation of numerous cysts , nephron loss , and interstitial fibrosis in polycystic kidney disease ( PKDleadingto the formation of numerous cysts , nephron loss , and interstitial fibrosis in polycystic kidney disease ( PKD
in acute kidney failureresultingin acute kidney failure
in lung tissueoriginatingin lung tissue
to the glomerular epithelial hyperplasiacontributeto the glomerular epithelial hyperplasia
in tissues within the pulmonary treeoriginatingin tissues within the pulmonary tree
from the renal pelvis , ureters , bladder and/or urethraoriginatefrom the renal pelvis , ureters , bladder and/or urethra
from the renal pelvis , ureters , urinary bladder and/or urethraoriginatefrom the renal pelvis , ureters , urinary bladder and/or urethra
an additional 30 gcontributean additional 30 g
an additional 30 g ... and a relatively smaller amount ( 2 g ) is derived from plasma proteins leaking into the lumencontributean additional 30 g ... and a relatively smaller amount ( 2 g ) is derived from plasma proteins leaking into the lumen