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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

certain duty or provision(passive) caused byself - repression

HDACs catalyze acetyl group removal from lysine residues in histones and non - histone proteinscausingtranscriptional repression

They catalyze acetyl group removal from lysine residues in histones and non - histone proteinscausingtranscriptional repression

in turncausesrelief of repression

by a specific structure , called and R - loop , that forms between the expanded repeat RNA and complementary genomic DNA(passive) is caused bytranscriptional repression

by a specific structure , called and R - loop , that forms between the expanded repeat RNA and complementary genomic DNA(passive) is causedtranscriptional repression

a specific structure , called and R - loop , that forms between the expanded repeat RNA and complementary genomic DNA(passive) is caused bytranscriptional repression

Bile acid - induced chromatin remodeling and histone deacetylation bothcontributeto transcriptional repression

The presence of a methyl group on the target sequence can affect the binding of the transcription factorcausingtranscriptional repression

Furthermore , DNA modifications in gene promoterscausetranscriptional repression

This DNA modification in gene promoterscausestranscriptional repression

can promote alterations in the methylation of histones and DNAleadingto transcriptional repression

gene promoter sequencesleadingto transcriptional repression

histone H3 lysine 27causingtranscriptional repression

Methylation at promoter CpG islandsleadsto transcriptional repression

lysine 9 of histone H3to causetranscriptional repression

by an R - loop that forms between the expanded repeat RNA and complementary genomic DNA(passive) is caused bytranscriptional repression

by an R - loop that forms between the expanded repeat RNA and complementary genomic DNA(passive) is causedtranscriptional repression

an R - loop that forms between the expanded repeat RNA and complementary genomic DNA(passive) caused bytranscriptional repression

to trimethyl lysine 9 of histone H3to causetranscriptional repression

histone H3to causetranscriptional repression

co - activator results in the recruitment of a transcriptional co - repressor Daxxthereby causingtranscriptional repression

the packaging of genes into chromatin(passive) caused bythe transcriptional repression

mutations in the MexEF - OprN efflux pump regulators ( mexS / T ) or the ParRS two - component system ( Li et al . , 2015(passive) caused byoprD repression

transcriptional deacetylation of promotersleadsto transcriptional repression

by these different HDAC genes(passive) caused bytranscriptional repression

promoter elementscausingtranscriptional repression

by chromatin modification or DNA methylation(passive) might be caused bytranscriptional repression

deacetylation of histone H4leadingto transcriptional repression

by histone acetylation(passive) caused bytranscriptional repression

chromatin modificationscausetranscriptional repression

histone deacetylasescausetranscriptional repression

on by ESET of dimethyl to trimethyl lysine 9 of histone H3to causetranscriptional repression

by abnormal expression of HDAC(passive) caused bytranscriptional repression

chromatin alterationscausetranscriptional repression

In its active state , CodY binds to DNA ,typically leadingto transcriptional repression

oncogenic proteins or silenced genes(passive) caused bytranscriptional repression

Alterations in the established epigenetic patterns ... gene expressioncan causetranscriptional repression

that in the presence of glucose , the Sin3 / Rpd3 repression complex may be part of the Ume6 / Ime1 complexthus contributingto transcriptional repression

the artificial methylation of CpG islandscausestranscriptional repression

to downregulation of expression of genes under its regulationleadingto downregulation of expression of genes under its regulation

to growth and proliferation of cellsleadingto growth and proliferation of cells

to apoptosisleadingto apoptosis

the growth defects(passive) caused bythe growth defects

transcriptional noisemay causetranscriptional noise

to late replicationmay contributeto late replication

to Doxorubicin Resistance in Breast Cancer CellsLeadsto Doxorubicin Resistance in Breast Cancer Cells

to neuronal deathleadsto neuronal death

to neuronal death or what forms that death might takeleadsto neuronal death or what forms that death might take

the reduced lysis rate in M9-glucose(passive) was ... caused bythe reduced lysis rate in M9-glucose

in a serious deterioration of human rights in Chinaresultingin a serious deterioration of human rights in China

in upregulation of E - cadherin through CBX7 , which we have shownresultingin upregulation of E - cadherin through CBX7 , which we have shown

to block of plasma cell differentiation in classical Hodgkin lymphomacontributesto block of plasma cell differentiation in classical Hodgkin lymphoma

in E - cadherin down - regulation and ESRP1 enforced expressionresultedin E - cadherin down - regulation and ESRP1 enforced expression

in cells accumulating micronuclei , a hallmark of chromosome missegregationalso resultsin cells accumulating micronuclei , a hallmark of chromosome missegregation

to greater protest and more intense repression and so onleadsto greater protest and more intense repression and so on

to greater protest and more intense repressionleadsto greater protest and more intense repression

22 dead people and 3 700 arrestscauses22 dead people and 3 700 arrests

to reduction or loss of proteincan leadto reduction or loss of protein

injuries , detentions , and deathscausesinjuries , detentions , and deaths

new nonviolent and public oppositioncausesnew nonviolent and public opposition

what conditions ... repression ... to international conflictdoes ... leadwhat conditions ... repression ... to international conflict

to increasing conflict and a struggle over the stateleadsto increasing conflict and a struggle over the state

to murder , arbitrary detentions , torture and forced relocation of peopleleadingto murder , arbitrary detentions , torture and forced relocation of people

numerous deathscausednumerous deaths

in greater repressionresultsin greater repression

to violent revolutionwill only leadto violent revolution

to public humiliation of the victims and deathledto public humiliation of the victims and death

to growing discontent and resistancewill ... leadto growing discontent and resistance

to massive underground resistancealmost always leadsto massive underground resistance

to anxiety , which leads to suppression of sexual activityleadsto anxiety , which leads to suppression of sexual activity

to suppression of sexual feelings , which leads to a reaction formationleadsto suppression of sexual feelings , which leads to a reaction formation

in the deathsresultingin the deaths

to radicalization of the movementledto radicalization of the movement

to a growing and more active community of human rights defendershas contributedto a growing and more active community of human rights defenders

to expressionleadsto expression

to expressionleadingto expression

in massive exodus of thousands of Ethiopianresultedin massive exodus of thousands of Ethiopian

to banleadingto ban

to violenceleadingto violence

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Smart Reasoning:

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