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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the mechanisms by whichinfluencetranscription factor dynamics;(2

pathwaysinfluencetranscription factor activity

small - molecule kinase inhibitorsinfluencingtranscription factor activity

by flagellin pretreatment(passive) caused bytranscription factor expression

of c - Fos and c - Jun(passive) is composedTranscription factor AP-1

Predictedto influencetranscription factor binding

of two subunits : c - fos and c - jun(passive) is composedAP-1 transcription factor

of c - Fos and c - Jun and mediates inflammation and carcinogenesis(passive) is composedTranscription factor AP-1

Because epigenetic modification of gene promoter regions has been shownto influencetranscription

Once in the nucleus , the GR - GC complex binds to the DNAinfluencingtranscription

Sequences near the coding regions of genes to which transcription factors can bindthus influencingtranscription

Estrogen binding induces ... this proteinpromptstranscription

our Transcription Times page for the factorsinfluencetranscription

The organization of genes within the nucleusmay influencetranscription

signal transduction ... a hormone or other chemical " binds " to it ) , or moleculescausetranscription

The location of an R - loop within the promotercould influencetranscription

by steroid hormones ( e.g. via a known estrogen receptor(passive) caused bytranscription

A secondary promotercausestranscription

vector ... a regulatory sequencecausestranscription

our Times page ... the factorsinfluencetranscription

the nucleusinfluencetranscription

Steroid hormones ... the nucleusinfluencetranscription

by the C(passive) caused bytranscription

the epigenetic condition from the sperm nucleuscould influencetranscription

1 s(passive) are designedTranscription

other sequencesinfluencingtranscription

This processwould resulttranscription

The enzymes which form the capalso influencetranscription

the protein ... sufficient strengthto influencetranscription

by stress(passive) caused bytranscription

inhibition of human Cdk7influencestranscription

which helpto influencetranscription

however(passive) can ... be influencedTranscription

Elimination of the TATA box in these genescausestranscription

by knockdown of(passive) caused bytranscription

mutation of Rb(passive) caused bythe ZEB1 transcription factor

The Catalytic sub - units make their way in to the nucleusto influencetranscription

orderto influencetranscription

/ short - techniquesdesignedtranscription

no longercan ... influencetranscription

to histone deacetylationleadto histone deacetylation

to significant off target binding in vivodoes ... leadto significant off target binding in vivo

to pleiotropic off - target effectscan leadto pleiotropic off - target effects

of FOS and c - JUN proteinscomposedof FOS and c - JUN proteins

to diseasemay contributeto disease

of proteins of the families Fos and Juncomposedof proteins of the families Fos and Jun

neural stem / progenitor cell differentiation and maturation in vivoinfluencesneural stem / progenitor cell differentiation and maturation in vivo

to both embryonic and adult neurogenesiscontributesto both embryonic and adult neurogenesis

to both embryonic and adult neurogenesis as a multifunctional regulatorcontributesto both embryonic and adult neurogenesis as a multifunctional regulator

global gene expression(passive) influenced byglobal gene expression

in cell - state specific modulation of transcriptionresultingin cell - state specific modulation of transcription

to progression through cell cycle Mutation in one alleleleadsto progression through cell cycle Mutation in one allele

in transcription of its target genesresultsin transcription of its target genes

to tissue - specific expressionmay potentially contributeto tissue - specific expression

to the expression of this geneleadingto the expression of this gene

to the expression of a geneleadingto the expression of a gene

to activation or silencing of genes important in cell differentiation and maintenanceleadingto activation or silencing of genes important in cell differentiation and maintenance

to the activation of proliferative genesleadingto the activation of proliferative genes

to induction or repression of thousands of genesleadingto induction or repression of thousands of genes

to upregulationleadingto upregulation

to changes in gene expressionleadto changes in gene expression

to changes in gene expressionwill leadto changes in gene expression

to changes in gene expressionleadingto changes in gene expression

to cellular responses such as cell proliferation , growth , motility , survival and apoptosisleadto cellular responses such as cell proliferation , growth , motility , survival and apoptosis

to silencing of specific gene expressionleadingto silencing of specific gene expression

to proliferation and inhibition of apoptosisleadingto proliferation and inhibition of apoptosis

to gene transcription differsleadingto gene transcription differs

AsA biosynthesis other than regulating gene transcriptionmay influenceAsA biosynthesis other than regulating gene transcription

to cellular regulationcontributeto cellular regulation

cancer through coordinated changes in gene expressioncausecancer through coordinated changes in gene expression

cellular activityinfluencecellular activity

in alterations of specific gene expressionresultingin alterations of specific gene expression

the activity of a promoter by binding to cis - acting DNA regulatory elements located within the proximal promoter of a gene or distant enhancer regionscan influencethe activity of a promoter by binding to cis - acting DNA regulatory elements located within the proximal promoter of a gene or distant enhancer regions

to cell proliferation and differentiationleadingto cell proliferation and differentiation

in generesultin gene

to the transcriptional activation of the P-450b / e genes in rat liverleadingto the transcriptional activation of the P-450b / e genes in rat liver

the binding of RNA polymerase to the promoterinfluencethe binding of RNA polymerase to the promoter

to the expression of a tau proteinleadto the expression of a tau protein

gene expressioninfluencegene expression

to gene expressionleadingto gene expression

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Smart Reasoning:

C&E

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