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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

drugscausetissue necrosis upon extravasation

by extravasation into subcutaneous tissue during intravenous administration(passive) caused bytissue necrosis

by ischemia due to vascular occlusion(passive) is caused bytissue necrosis

the subcutaneous tissue and fascia characterized by vascular thrombosisleadsto tissue necrosis

however , following a stroke has two causes : 1 ) ischemic injury and 2 ) reperfusion injuryResultingtissue necrosis

when non pressure related disruption or blockage of the arterial blood flow to an areacausestissue necrosis

extravasation into subcutaneous tissue during infusioncan causetissue necrosis

tissue ischemiamay leadto tissue necrosis

an intense inflammatory response in the blood vessels and surrounding cellsresultsin tissue necrosis

by local vascular occlusion(passive) caused bytissue necrosis

The toxic effect on the cellscausestissue necrosis

by inflammation or injury(passive) caused bytissue necrosis

Extravasation at site of intravenous administrationmay leadto tissue necrosis

excessive tissue - pinching pressurecould causenecrosis of the tissue

the tissue ... a temperaturedoes ... causetissue necrosis

the blood and tissuescausingtissue necrosis

the myocardial tissuecausingtissue necrosis

by prolonged pressure on them(passive) caused bynecrosis of tissue

Microcirculation disturbance cause ischemic cell injury , development of dystrophic disorders and in critical hypoxiacausedtissue necrosis

When focused ultrasound waves pass through a tissue it causes local rise of temperatureto causetissue necrosis

impaired arterial or venous blood supply due to mechanical factors ( e.g. , emboli , thrombi ) or to blood pressure alterations(passive) caused bytissue necrosis

Later in the course of injury there is also a loss of blood supplycausingtissue necrosis

Exposure to severe coldmay leadto tissue necrosis

by inadequate tissue perfusion and/or oxygenation(passive) caused byTissue necrosis

the skin ... in turncausestissue necrosis

Prolonged limb ischemiaresultingin tissue necrosis

Occlusion of small vesselscausestissue necrosis

It may be severe enough that thrombosis and vascular compromise occurcausingtissue necrosis

Extravasation of the injectionmay causetissue necrosis

vascular obstructioncausingtissue necrosis

insufficient oxygen and nutrients ... the tissuemay leadto tissue necrosis

to target tissueto causetissue necrosis

by intramuscular drug injection(passive) caused byTissue necrosis

ischemic cell injury , development of dystrophic disorders andcausedtissue necrosis

a vascular occlusionleadingto tissue necrosis

Vascular occlusionleadingto tissue necrosis

a bite from a Brown Recluse Spidercausingtissue necrosis

excessive local heatingmay causetissue necrosis

Lack of oxygen supply ( ischemiacausestissue necrosis

insufficient coronary blood flowcausingnecrosis of tissue

paincausingpain

from insufficient blood supplyresultingfrom insufficient blood supply

from the removal of lymph nodesresultsfrom the removal of lymph nodes

in gangrenemay resultin gangrene

from aggressive infiltration of blood vessels and subsequent formation of blood clotsresultsfrom aggressive infiltration of blood vessels and subsequent formation of blood clots

insufficient blood flow to the tissues and causes them to die resulting to further complicationscausesinsufficient blood flow to the tissues and causes them to die resulting to further complications

to inflammation and cellular destructionleadsto inflammation and cellular destruction

in infection , shock , and deathresultingin infection , shock , and death

in amputation and deathmay resultin amputation and death

to reduction in volume of tissueleadsto reduction in volume of tissue

to skin ulceration and other complicationsmay leadto skin ulceration and other complications

from the expansion pressure on the surrounding bonewould ... resultfrom the expansion pressure on the surrounding bone

to gangrene or deathleadingto gangrene or death

in abscess formationresultsin abscess formation

edema and ischemia resulting in metabolic acidosis , fever , and kidney failurethen causesedema and ischemia resulting in metabolic acidosis , fever , and kidney failure

to the formation of an ulcerleadingto the formation of an ulcer

to deathcan leadto death

to deathledto death

to deathleadto death

to organ failure and deathleadingto organ failure and death

Pain(passive) is caused byPain

from inflammationresultingfrom inflammation

to gangrene which further need to amputationleadsto gangrene which further need to amputation

in the continuous release of inflammatory factors into the bodyresultsin the continuous release of inflammatory factors into the body

the healing complications(passive) were causedthe healing complications

from cavitation activity , which causes tissue and cellular disorganizationalso resultsfrom cavitation activity , which causes tissue and cellular disorganization

by that infectionsetby that infection

damage(passive) caused bydamage

to loss of limbscan leadto loss of limbs

to clinical complicationscan leadto clinical complications

edema and ischemia resulting in metabolic acidosis , fever , and renal failure.[3then causesedema and ischemia resulting in metabolic acidosis , fever , and renal failure.[3

from reduction or loss of blood supplyresultingfrom reduction or loss of blood supply

a systemic inflammatory response syndromecausinga systemic inflammatory response syndrome

insufficient blood flow to the tissuescausesinsufficient blood flow to the tissues

from ischemiaresultingfrom ischemia

edema and ischemia resulting in metabolic acidosis , fever , and kidney failure.[4then causesedema and ischemia resulting in metabolic acidosis , fever , and kidney failure.[4

to permanent scarleadingto permanent scar

to amputationleadingto amputation

in amputationresultingin amputation

in perforationsometimes resultingin perforation

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Smart Reasoning:

C&E

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