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Qaagi - Book of Why

Causes

Effects

Repeated doses in the same spotmay causescarring , tissue atrophy

IM drugs - Depot injectionsmay causelocal tissue atrophy

the continuous stimulation over timemight causetissue deterioration

Bone inflammation ... bonescausestissue deterioration

by extravasation into subcutaneous tissue during intravenous administration(passive) caused bytissue necrosis

likelyto causetissue deterioration

by ischemia due to vascular occlusion(passive) is caused bytissue necrosis

when non pressure related disruption or blockage of the arterial blood flow to an areacausestissue necrosis

The partscan causetissue deterioration

bonescausestissue deterioration

his advancing age and training(passive) caused bytissue deterioration

by local vascular occlusion(passive) caused bytissue necrosis

these injectionscausingtissue deterioration

Bone inflammation ... enlargement and deformation of bonescausestissue deterioration

the myocardial tissuecausingtissue necrosis

When focused ultrasound waves pass through a tissue it causes local rise of temperatureto causetissue necrosis

impaired arterial or venous blood supply due to mechanical factors ( e.g. , emboli , thrombi ) or to blood pressure alterations(passive) caused bytissue necrosis

by inadequate tissue perfusion and/or oxygenation(passive) caused byTissue necrosis

muscle tissuecausestissue deterioration

Extravasation of the injectionmay causetissue necrosis

by intramuscular drug injection(passive) caused byTissue necrosis

Periodontal disease ... that it has begunto causetissue deterioration

by impairment of arterial or venous blood supply(passive) caused bytissue necrosis

that thrombosis and vascular compromise occurcausingtissue necrosis

Subcutaneous injectioncan causetissue necrosis

Extravasation of the drugmay causetissue necrosis

cellscausingtissue necrosis

by the infection(passive) caused bytissue necrosis

their infectioncausestissue necrosis

by brown recluse bites(passive) caused bytissue necrosis

abundant protease activity(passive) caused bytissue deterioration

repeated injection at the fixed sitecan causetissue necrosis

repeated injection at the fixed sitecan causetissue necrosis

by a lack of blood supply to the affected region(passive) caused bytissue necrosis

inflammatory proteinscausetissue necrosis

The diseasecausestissue necrosis

by disease(passive) caused bytissue necrosis

a localized process , it can invade nearby structures and/or blood vesselscausingtissue necrosis

As a localized process , it can invade nearby structures and/or blood vesselscausingtissue necrosis

enlargement and deformation of bonescausestissue deterioration

to discomfortleadsto discomfort

incontinencecausingincontinence

to systemic inflammationleadsto systemic inflammation

to disease , joint and back pains , and cancerleadsto disease , joint and back pains , and cancer

the pain(passive) is being caused bythe pain

in aging and diseaseresultsin aging and disease

the inflammation of the tendoncausingthe inflammation of the tendon

to inflammation and cellular destructionleadsto inflammation and cellular destruction

due to agingresultingdue to aging

Other problems(passive) are caused byOther problems

from arthritisoriginatesfrom arthritis

to neurological dysfunctionleadingto neurological dysfunction

cardiac diseases(passive) caused bycardiac diseases

to early agingleadingto early aging

chronic paincausingchronic pain

to complete disruption and instability of the lesion ( loose bodyleadingto complete disruption and instability of the lesion ( loose body

in amputation and deathmay resultin amputation and death

to diseases such as Alzheimer 'smay leadto diseases such as Alzheimer 's

to reduction in volume of tissueleadsto reduction in volume of tissue

to skin ulceration and other complicationsmay leadto skin ulceration and other complications

in OAresultingin OA

edema(passive) caused byedema

to decreased gene expression , andleadingto decreased gene expression , and

illnesses(passive) caused byillnesses

edema and ischemia resulting in metabolic acidosis , fever , and kidney failurethen causesedema and ischemia resulting in metabolic acidosis , fever , and kidney failure

to deathledto death

to deathcan leadto death

to organ failure and deathleadingto organ failure and death

to persistent chronic inflammationleadingto persistent chronic inflammation

thereforeresultstherefore

in the continuous release of inflammatory factors into the bodyresultsin the continuous release of inflammatory factors into the body

to tooth lossleadsto tooth loss

by that infectionsetby that infection

in loss of elasticity and stretching of skinresultingin loss of elasticity and stretching of skin

in the loss of elasticity and stretching of the skinresultsin the loss of elasticity and stretching of the skin

in a loss of elasticity and stretching of the skinresultingin a loss of elasticity and stretching of the skin

in loss of elasticity and stretching of the skinresultingin loss of elasticity and stretching of the skin

to loss of limbscan leadto loss of limbs

if not repairedleadsif not repaired

edema and ischemia resulting in metabolic acidosis , fever , and renal failure.[3then causesedema and ischemia resulting in metabolic acidosis , fever , and renal failure.[3

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