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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

the mechanisms by whichcontributesto the pathology of the disease using in vitro and in vivo models

Our studies in this regardhave ledto the development of more relevant in vitro and in vivo models of neisserial infection and disease

the stage - specific fluorescence expression by PLK / Bimay be ... designedfor in vitro and in vivo studies on stage conversion and reactivation of T. gondii

At first , you will work closely with our chemists , radiochemists and biologiststo designthe probe and test it using in vitro and in vivo pre - clinical models

moderate evidencecausesimmunosuppression , based on in - vivo and in - vitro studies

DNA double strand breaks in epidermal cellscauseimmune suppression in vivo and cytokine production in vitro

O'Connor A , et al . , DNA double strand breaks in epidermal cellscauseimmune suppression in vivo and cytokine production in vitro

to DNAresultingin resistance to PARPi therapy in vitro and animal models in vivo

that acute exposure to Pbcan leadto glial activation and secretion of cyto - chemokines in both in vitro and in vivo models

Conventional culture of primary cells on rigid and hydrophobic plastic surfaces may cause phenotypic alterationscontributingto the discrepancy between in vivo and in vitro biological models

Mnk inhibitorscauseremission of leukemia in vitro and in vivo in preclinical models

Vascular endothelial growth factor ( VEGFcausesendothelial cell proliferation in vitro and angiogenesis in vivo

factorsinfluencingGnRH - mediated cell growth inhibition in vitro and in vivo

this diversitycould influenceantibiotic susceptibility in vivo and in vitro

Ectopic expression of BANCR impaired cell viability and invasionleadingto the inhibition of metastasis in vitro and in vivo

which have been foundto influenceadherence in vitro and colonization in vivo

thermal precondition of glioma cells ... an effective wayto influencethe in vitro and in vivo oncological contour of glioma cells

inflammationcausingmediators in in vitro and in vivo models

oxidative stresscontributeto antitumor responses in vitro and in vivo

Peroxynitritecan provokethe nitration of tyrosine residues both in vitro and in vivo

regulate integrin functionleadingto the intratumoral angiogenesis both in vitro and in vivo

down - regulationinfluencesneuronal arborization in vitro and in vivo

vessel - residing endothelial stem / progenitor cellscontributingto angiogenesis in vitro and in vivo

a key role in ALCL lymphomagenesis ... has been shownto causelymphoid malignancy in vitro and in vivo

Study of the Effects(passive) Caused byStudy of the Effects

in highly potent antitumor activityresultedin highly potent antitumor activity

to the identification of the following distribution of macromolecular componentsledto the identification of the following distribution of macromolecular components

to some key discoveries and therapies in the pasthave ledto some key discoveries and therapies in the past

Several approaches(passive) have been designedSeveral approaches

novel gene fusion , LAMTOR1-AKT1discoverednovel gene fusion , LAMTOR1-AKT1

to our understanding of the disease mechanismshave contributedto our understanding of the disease mechanisms

from lung or breast canceroriginatingfrom lung or breast cancer

disease severityto influencedisease severity

to apoptotic cell deathleadsto apoptotic cell death

myeloid expansion and blocks both erythropoiesis and lymphopoiesiscausesmyeloid expansion and blocks both erythropoiesis and lymphopoiesis

to a large range of health problems in humans , such as polycystic ovarian syndrome , immune response to allergens , behavioral problems and decreased fertilitycontributesto a large range of health problems in humans , such as polycystic ovarian syndrome , immune response to allergens , behavioral problems and decreased fertility

to the development of a number of mixed molecules targeted to Mu and NOPhave subsequently ledto the development of a number of mixed molecules targeted to Mu and NOP

postharvest decay of peanut kernels(passive) caused bypostharvest decay of peanut kernels

to the hypothesis that the gene Metadherin ( MTDH ) was the functional target of this amplificationledto the hypothesis that the gene Metadherin ( MTDH ) was the functional target of this amplification

in isolation and identification of several different bioactive moleculesresultingin isolation and identification of several different bioactive molecules

how bone would respond to smooth - surface PEEK , porous PEEK , and micro - textured titanium plasma - coated PEEKto discoverhow bone would respond to smooth - surface PEEK , porous PEEK , and micro - textured titanium plasma - coated PEEK

to the anti - metastatic effects of curcumincould contributeto the anti - metastatic effects of curcumin

to the antimetastatic effects of curcumin " Curcumin treatmentcould contributeto the antimetastatic effects of curcumin " Curcumin treatment

to the antimetastatic effects of curcumincould contributeto the antimetastatic effects of curcumin

to the antimetastatic effects of curcumincould contributeto the antimetastatic effects of curcumin

to the antimetastatic effects of curcumin " - See curcumin productscould contributeto the antimetastatic effects of curcumin " - See curcumin products

to the antimetastatic effects of curcumin " - See curcumin products at Amazon.comcould contributeto the antimetastatic effects of curcumin " - See curcumin products at Amazon.com

to activation of ERK1/2 kinases in a variety of cell types ( Howlett 2005leadsto activation of ERK1/2 kinases in a variety of cell types ( Howlett 2005

translational therapywill ... causetranslational therapy

to translational therapywill ... leadto translational therapy

to the hypothesis that C. albicans possesses putative cholinergic receptors ( 17 , 30leadingto the hypothesis that C. albicans possesses putative cholinergic receptors ( 17 , 30

Future studies(passive) will be designedFuture studies

the oxidative DNA damage(passive) caused bythe oxidative DNA damage

to the antimetastatic effects of curcumincould contributeto the antimetastatic effects of curcumin

to endothelial dysfunction and vascular diseasescontributesto endothelial dysfunction and vascular diseases

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Smart Reasoning:

C&E

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