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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

Absence of one beta genecausesbeta thalassemia trait

a gene defect(passive) is caused byHemoglobin E trait

changes ( mutations ) to the HFE gene associated with hemochromatosis(passive) is caused byHereditary hemochromatosis

a mutation in a gene that controls how much iron the body absorbs from food(passive) is caused byHereditary hemochromatosis

a mutation in the hemochromatosis gene ( HFE(passive) is most commonly caused byHereditary hemochromatosis

changes in the HFE gene(passive) is usually caused byHereditary hemochromatosis

a mutation in a gene that controls the amount of iron your body(passive) is caused byHereditary hemochromatosis

a mutation in a gene that controls the amount of iron your body absorbs from the food you eat(passive) is caused byHereditary hemochromatosis

by a mutation in a gene that controls the amount of iron your body absorbs from the food you eat(passive) is caused byHereditary hemochromatosis

certain variants in the HFE gene(passive) is most commonly caused byHereditary hemochromatosis

by a defect in a gene called HFE , which helps regulate the amount of iron absorbed from food(passive) is ... caused byHereditary hemochromatosis

a defect in a gene called HFE , which helps regulate the amount of iron absorbed from food(passive) is mainly caused byHereditary hemochromatosis

by mutations in the hemochromatosis(passive) is caused byHereditary hemochromatosis

mutations of a gene that controls the amount of iron that the body absorbs from the foods you eat(passive) is caused byHereditary hemochromatosis

the mutationscausehereditary hemochromatosis

This blood test ... the gene changescausehereditary hemochromatosis

The genecauseshereditary hemochromatosis

defects in a gene called HFE(passive) is caused byHereditary hemochromatosis

This assay ... the mutationscausehereditary hemochromatosis

Hepcidin deficiencycauseshereditary hemochromatosis

HFE gene mutationcausinghereditary hemochromatosis

inheriting an alteration , or mutation , in a gene that causes the body to store too much iron(passive) is caused byHereditary hemochromatosis

the study of a mutation in the human hemochromatosis protein ( HFEcauseshereditary hemochromatosis

due to the mutation of that gene and such mutated genes(passive) is causedHereditary hemochromatosis

inherited defects in hepcidin production(passive) is caused byHereditary hemochromatosis

two common mutationscausehereditary hemochromatosis

due to the mutation of that gene and(passive) is causedHereditary hemochromatosis

which is knownto causehereditary hemochromatosis

the most common gene mutationcausinghereditary hemochromatosis

by gene mutations(passive) caused byautosomal recessive trait

How mutantcauseshereditary hemochromatosis

certain combinations of genetic variants(passive) is caused byHereditary hemochromatosis

an as - yet unidentified genetic mutation(passive) caused byhereditary hemochromatosis

inherited mutations that decrease the synthesis of either alpha or beta globin chains of hemoglobin(passive) are caused byThalassemia syndromes

Primary hyperoxaluria alanine - glyoxylate aminotransferase deficiencycausesautosomal recessive traits

some informationdiscoveredabout Thalassemia trait

Analysis of experimental multi - parent populations to detect regions of the genome ( called quantitative trait loci , QTLsinfluencingphenotypic traits

by a single gene mutation(passive) caused byrecessive trait

high plasma iron content exceeding transferrin iron - building capacity and normal erythropoiesis(passive) caused byhereditary hemochromatosis

by a mutation on a gene(passive) caused byrecessive trait

a mild anemiacausesa mild anemia

a mild anemia.[30causesa mild anemia.[30

any health problemsdoes ... causeany health problems

mild anemia and small red blood cellscan causemild anemia and small red blood cells

anemia and small red blood cellscausesanemia and small red blood cells

Mild anemia(passive) caused byMild anemia

no symptomscausesno symptoms

any health problemsdoes ... causeany health problems

the body to absorb too much iron from the foods you eatcausesthe body to absorb too much iron from the foods you eat

the body to absorb too much iron from the gutcausesthe body to absorb too much iron from the gut

excess iron to be deposited in various organscausesexcess iron to be deposited in various organs

mild anemia andcan causemild anemia and

a progressive loading of ironcausesa progressive loading of iron

from defects in the HFE generesultsfrom defects in the HFE gene

due to the genotypeis ... influenceddue to the genotype

to cancer and heart diseasecan also leadto cancer and heart disease

from a genetic mutationresultsfrom a genetic mutation

no symptomsmay causeno symptoms

and iron stores returned to normal before damage to organs occursis discoveredand iron stores returned to normal before damage to organs occurs

both systolic and diastolic dysfunction in patientsmay causeboth systolic and diastolic dysfunction in patients

health problemscauseshealth problems

health problemscauseshealth problems

at any agecould causeat any age

red blood cells to be a slightly smaller sizecausesred blood cells to be a slightly smaller size

to yieldcontributedto yield

to adaptation and estimating the strength of selection on these traits ( Arnqvist 1992contributeto adaptation and estimating the strength of selection on these traits ( Arnqvist 1992

to destruction of lung tissueleadingto destruction of lung tissue

mice to run in circles onlycausesmice to run in circles only

melanismcausingmelanism

problems based on the severity of the anemiacan causeproblems based on the severity of the anemia

mild or severe anemia , which is when your body does not have enough red blood cells or hemoglobincan causemild or severe anemia , which is when your body does not have enough red blood cells or hemoglobin

milder anemia that rarely requires transfusionscausesmilder anemia that rarely requires transfusions

the body to make less hemoglobin than normal , leading to anemiacausesthe body to make less hemoglobin than normal , leading to anemia

problemscan causeproblems

to the production of fewer red blood cells and less hemoglobin , a protein that carries oxygen throughout the bodytypically leadsto the production of fewer red blood cells and less hemoglobin , a protein that carries oxygen throughout the body

severe anemiacausessevere anemia

to severe anemialeadsto severe anemia

severe anemia(passive) caused bysevere anemia

low levels of red blood cells ( anemiacan causelow levels of red blood cells ( anemia

significant complications , including iron overload , bone deformities and cardiovascular illnesscan causesignificant complications , including iron overload , bone deformities and cardiovascular illness

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Smart Reasoning:

C&E

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