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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

7 Factorsinfluencingsolubility Temperature Heat of solution

when they dissolved solids in waterdiscoveredthat temperature has an effect on the solubility of the solid

the OH addedcauseda temperature - solubility change

Factorsinfluencesolubility # 1 TEMPERATURE

a decrease in the particle sizecausesan increase in the solubility

groupscausingwater solubility

by the addition of large amount of a second solute [ 7(passive) caused bywater solubility

A factorinfluencingwater solubility

representing not function moleculesinfluencingwater solubility

since this predicts the connection for not function moleculesinfluencingwater solubility

Amino acids will be bound in the coreto contributewater solubility

complexation of the porphyrin which is sparingly soluble in this solvent in its pure form(passive) caused byincreased solubility

This combination of persistence ( over months or years ) andhas ledsolubility in water

This combination of persistence ( over months or years ) andleadssolubility in water

a groupcontributingtoward solubility

a methyl group or the likecontributingtoward solubility

The presence of saltscould have causedoverestimation of aqueous solubility

potential drugsmay influencecystine solubility

the factorsinfluencingsolubility of solids

Factors derived from other connective tissues such as plasma and synovial fluidalso influencedurate solubility

the increased osmotic pressureinfluencingsolubility of erythropoietin

data ... the relative solubility of salts in terms of factors ( common ions , pHinfluencethe solubility

factors ( common ions , phinfluencethe solubility

the following reactions(passive) is influenced bythe solubility of AgCl

data ... factors ( common ions , pHinfluencethe solubility

data regarding the relative solubility of salts in terms of factors ( common ions , pHinfluencethe solubility

Temperature ... the factorsinfluencesolubility

the temperature of the solution(passive) is influenced bySolubility

The presence of other solutes in the solventcan also influencesolubility

by the presence of functional groups(passive) caused bysolubility

by the presence of an ion of a salt which is added to the solution of the salt from the external source(passive) caused bysolubility

the nature of surface groups(passive) is strongly influenced bysolubility

I can interpret data regarding the relative solubility of salts in terms of factors ( common ions , pHinfluencethe solubility

by the presence of a common ion(passive) caused bysolubility

the effect temperature , pressure and other factorsinfluencesolubility

pH valueinfluencedthe solubility

Temperature ... likelyto influencesolubility

salt forms of the drugsinfluencesthe solubility

these factorsmight influencesolubility

Other factorsinfluencingsolubility

The latter(passive) is caused byThe latter

the solubility productcan be ... influencedthe solubility product

to low dissolution and hence bioavailabilityleadsto low dissolution and hence bioavailability

the layer compositiondoes ... influencethe layer composition

in low bioavailability after aloneresultsin low bioavailability after alone

to total absorptiondefinitely leadsto total absorption

to development of more soluble semi - synthetic derivativesledto development of more soluble semi - synthetic derivatives

scale deposits to dissolvecausesscale deposits to dissolve

scale deposits to dissolvewill causescale deposits to dissolve

in the generation of misleading or inaccurate data , result in project delays and ultimately increase the overall cost of a projectcan resultin the generation of misleading or inaccurate data , result in project delays and ultimately increase the overall cost of a project

in a cloudy appearanceresultsin a cloudy appearance

through aqueous phasesCan influencethrough aqueous phases

in a greater dispersion of phytocannabinoids in the formulationresultsin a greater dispersion of phytocannabinoids in the formulation

in a greatly increased rate of absorption and effectiveness for optimal resultsresultsin a greatly increased rate of absorption and effectiveness for optimal results

permeationCan influencepermeation

permeation through aqueous phasesCan influencepermeation through aqueous phases

to a better dispersion of phytocannabinoids in the formulaleadsto a better dispersion of phytocannabinoids in the formula

permeation via aqueous phasescan influencepermeation via aqueous phases

to a greater dispersion of phytocannabinoids in the methodleadsto a greater dispersion of phytocannabinoids in the method

the CCN activation for sparingly soluble compounds with 10 - 4 < C<0.05can ... influencethe CCN activation for sparingly soluble compounds with 10 - 4 < C<0.05

to poor dissolution and bioavailabilityleadsto poor dissolution and bioavailability

inescapably to the conclusion that one desiring to practice appellant 's inventionleadsinescapably to the conclusion that one desiring to practice appellant 's invention

the environmental fate and persistence of an herbicide ( Westerdahl and Getsinger 1988can ... influencethe environmental fate and persistence of an herbicide ( Westerdahl and Getsinger 1988

to treat a 24-hr periodleadingto treat a 24-hr period

even more useful tipswill discovereven more useful tips

from high Sn compositionresultingfrom high Sn composition

to precipitation of mineral saltsleadto precipitation of mineral salts

in poor bioavailabilitycan resultin poor bioavailability

to improved bioavailabilityleadsto improved bioavailability

both the rate and site of absorptionwill influenceboth the rate and site of absorption

to the potential variation in IC50contributesto the potential variation in IC50

into low dissolution and poor bioavailability after oral administrationresultsinto low dissolution and poor bioavailability after oral administration

into low dissolution and poor bioavailabilityresultsinto low dissolution and poor bioavailability

in high dissolution rate and bioavailability of this essentially poorly water soluble drug LMNresultingin high dissolution rate and bioavailability of this essentially poorly water soluble drug LMN

to failure in formulation developmentwould leadto failure in formulation development

to precipitationleadingto precipitation

to the formation of aggregates already in the solutioncan leadto the formation of aggregates already in the solution

Formulation _resultsFormulation _

Formulation _resultsFormulation _

to potential changes in toxicity and effects on non - target organismsleadingto potential changes in toxicity and effects on non - target organisms

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Smart Reasoning:

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