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This mutationleadsto a lack of inhibition of the JH1 domain and constitutive JAK2 kinase activity
in turnleadsto inhibition of PP1 activity and changes in the actin cytoskeleton
HFDleadingto phosphorylation and inhibition of G6PD activity causing decrease in NADPH
In addition to ammonia , amino acids enter the brain tissues , which are concentrated in its structurescausinginhibition of the enzyme system and inhibition of CNS functions
Exogenous expression of Meqresultedin the inhibition of p53-mediated transcriptional activity and apoptosis
the metal toxicityleadingto inhibition on microbial growth and activity
Ethanol in Neonatal Rats In Vivo(passive) Caused byInhibition of Cortical Activity and Apoptosis
small amountscausingvasodilation and inhibition of platelet and leukocyte activity
The CZEOcausedconsiderable inhibition of acetylcholinesterase and butyrylcholinesterase enzyme activities
The immunosuppressive properties of rapamycinmainly resultfrom the inhibition of leukocyte activity and cytokine expression
controlling the phosphorylation , dephosphorylation , acetylation , succinylation and oxidation of enzymesresultingin the activation and inhibition of enzymatic activity
Manganese ions and cyanides or sulfidescausedactivation and inhibition of the activity of the enzyme
as 100 % ( 5290 U / ml(passive) was setActivity without detergents and enzyme inhibitors
HIF-1-mediated induction of PDK1normally leadsto phosphorylation of PDH and inhibition of PDH activity
Mobile phone exposurecausedan inhibition in 5'-nucleotidase and catalase enzyme activities
RhoAleadingto inhibition of RhoA and Rho kinase activities
Psychogenic stress in rabbitscausedinhibition of contractile activity ( CA ) in antral and pyloric
eIF4Aresultsin the inhibition of helicase activity and translation
their intrinsic muscle composition propertiesinfluencingMMb reducing activity and endogenous enzyme activity
an orally administrated therapydesignedto inhibit the activity of the ALK , ROS1 , and TRK enzymes
while damageto causesenzyme inhibition , denaturation and proteasome
flavonoidsleadingto the inhibition of enzyme activity [ 26,52
to the cancer preventive effect of Morinda citrifoliamay contributeto the cancer preventive effect of Morinda citrifolia
to light chainleadingto light chain
to the increase of NO bioavailabilityleadingto the increase of NO bioavailability
in the reduction of intracellular cAMP synthesisresultingin the reduction of intracellular cAMP synthesis
in decreased NO bioavailability and endothelial dysfunctionresultingin decreased NO bioavailability and endothelial dysfunction
in chromosomal instability , cell cycle arrest and subsequent apoptosisresultingin chromosomal instability , cell cycle arrest and subsequent apoptosis
to elevated exposure to tamsulosin hydrochloridemight leadto elevated exposure to tamsulosin hydrochloride
to elevated exposure to tamsulosin hydrochloridecould leadto elevated exposure to tamsulosin hydrochloride
to increased exposure to tamsulosin hydrochloridemay leadto increased exposure to tamsulosin hydrochloride
to germ cell migration defects as well as intracerebral hemorrhagecan leadto germ cell migration defects as well as intracerebral hemorrhage
to the degradation of client proteinsleadsto the degradation of client proteins
to arrest of DNA synthesis and cell deathleadsto arrest of DNA synthesis and cell death
in microtubules depolymerizationresultingin microtubules depolymerization
in clinical drug interactionsmay resultin clinical drug interactions
to dephosphorylation of Ser910 / Ser935leadsto dephosphorylation of Ser910 / Ser935
to dephosphorylation of Ser(910)/Ser(935leadsto dephosphorylation of Ser(910)/Ser(935
Figcan leadFig
generallyleadsgenerally
telomere shorteningcausedtelomere shortening
in reduced cytoprotectionresultedin reduced cytoprotection
alsoledalso
to delayed cone cell deathcontributedto delayed cone cell death
to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cellsleadsto epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells
to a modulation in the growth rate of cancer cells without disturbing the function of the surrounding cellsleadsto a modulation in the growth rate of cancer cells without disturbing the function of the surrounding cells
to a modulation in the growth rate of cancer cellsleadsto a modulation in the growth rate of cancer cells
in down regulation of various cytoskeletal proteins with correlative evidence of the involvement of telomerase in regulating the expression of vimentinresultedin down regulation of various cytoskeletal proteins with correlative evidence of the involvement of telomerase in regulating the expression of vimentin
to delayed cone cell death in pde6cw59 mutant zebrafishcontributedto delayed cone cell death in pde6cw59 mutant zebrafish
to cell lysis in CD38-expressing tumour cellsleadingto cell lysis in CD38-expressing tumour cells
to this increase and whether Na+/K+ ATPase activity can be maintained by provision of glucose to perfused rat hearts during low flow , 0.5 ml / min , ischemiacontributesto this increase and whether Na+/K+ ATPase activity can be maintained by provision of glucose to perfused rat hearts during low flow , 0.5 ml / min , ischemia
severe diarrheacausingsevere diarrhea
in intracellular buildup of toxic concentrations of hydrogen peroxide and in candida albicans , econazol inhibits transformation of blastospores into the invasive mycelial formresultingin intracellular buildup of toxic concentrations of hydrogen peroxide and in candida albicans , econazol inhibits transformation of blastospores into the invasive mycelial form