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Qaagi - Book of Why

Causes

Effects

a mutant alleleis causingdecreased activity of an enzyme involved in heme biosynthesis

the presence of an organic substance or inorganic metal or biosynthetic compound due to their covalent or non - covalent interactions with enzyme active site resulting in a decrease , reduction or termination of the enzyme activity during biological reaction(passive) influenced byenzyme - substrate activity

Factorsinfluencingenzyme activity Types of enzyme inhibition

by the presence of an organic substance or inorganic metal or biosynthetic compound(passive) influenced byenzyme - substrate activity

Bronidoxcausesinhibition of enzyme activity in bacteria

Covalent binding and protein loadingcan influencethe activity retention of enzyme

a characteristic colorresultsfrom the activity of the enzyme on the substrate

the oxidative damage(passive) could be ... caused byexpression due to attenuated enzyme activity

metabolismcausingdeficient activity of the enzyme

something in royal jellyinfluencesthe activity of the methylation enzyme

the cell(passive) is influenced byactivity of an enzyme

Factorsinfluencingenzyme activity Types of enzyme

factorsinfluencingenzyme activity Background Enzymes

some other site on the proteinleadingto allosteric inhibition of enzyme activity

flavonoidsleadingto the inhibition of enzyme activity [ 26,52

the proteinleadingto allosteric inhibition of enzyme activity

These data ... multiple polyphenols in GEcould be contributingto the inhibition of DGAT1 enzyme activity

the minimal effect of L - serine bindingleadingto inhibition of enzyme activity

the presence of inhibitorresultedin the inhibition of enzyme activity

all parametersinfluencesubstrate concentrations or enzyme activity

the use of growth - inhibiting concentrationsprovokedinhibition of the enzyme activity

Accumulation of Product in a reactioncausesinhibition of enzyme activity

the minimal effect of l - serineleadingto inhibition of enzyme activity

product accumulationmay causeinhibition of enzyme activity

product accumulationmight causeinhibition of enzyme activity

lignin exposureleadsto inhibition of enzyme activity

by the compounds ( I(passive) is causedthe inhibition of enzyme activity

membraneresultsfrom inhibition of enzyme activity

Excess substratecausesinhibition of enzyme activity

ATPasecausinginhibition of the enzyme activity

the , necessary conformational changesleadingto inhibition of enzyme activity

variations in hand pipetting or liquid handling instrumentation(passive) caused bysubstrate concentration

Incubation of GAPDH with GSNO or DEANO ( an NO donorleadsto inhibition of enzyme activity

Factorsinfluencingextracellular enzyme activity

Contents 1 Factorsinfluencingextracellular enzyme activity

Mutationsleadingto residual enzyme activity

different gene mutations(passive) caused byresidual enzyme activity

To testpromptedlowered enzyme activity

by grapefruit juice(passive) caused byCYP3A4 enzyme activity

to arrest of DNAleadsto arrest of DNA

to arrest of DNA synthesis and cell deathleadsto arrest of DNA synthesis and cell death

to arrest of DNA synthesis and cell deathleadsto arrest of DNA synthesis and cell death

to an increase in the content of noradrenaline and serotonin in the brain , which in turn eliminates the biochemical cause of depressionleadsto an increase in the content of noradrenaline and serotonin in the brain , which in turn eliminates the biochemical cause of depression

thereforemay ... influencetherefore

the efficacy of these drugswill influencethe efficacy of these drugs

the efficacywill influencethe efficacy

the substrate to release fluorescent productswill causethe substrate to release fluorescent products

to decreased degradation of the substrateleadsto decreased degradation of the substrate

to severe health effectsleadingto severe health effects

to the production of HDL cholesterolcontributesto the production of HDL cholesterol

in fewer carbs being broken down into simple sugars allowing blood sugar to stay more stableresultsin fewer carbs being broken down into simple sugars allowing blood sugar to stay more stable

urea to break downcan causeurea to break down

a measurable reactioncausesa measurable reaction

to a marked drop in the initial reaction rate and the maximum yield , possibly caused by the substrate inhibition at high concentrations of substrateledto a marked drop in the initial reaction rate and the maximum yield , possibly caused by the substrate inhibition at high concentrations of substrate

Allosteric Enzymes(passive) are influenced byAllosteric Enzymes

to the deterioration of foods qualitycan leadto the deterioration of foods quality

in an accumulation of oleic acidresultsin an accumulation of oleic acid

to disease statescan leadto disease states

In Antiproliferative And Anti - Inflammatory EffectsResultingIn Antiproliferative And Anti - Inflammatory Effects

to rapid glucoseleadingto rapid glucose

in decrease of serum LDL levelsresultingin decrease of serum LDL levels

to degradationcan leadto degradation

to increased mineralization of organic matter and improved resistance against pests and diseasesleadingto increased mineralization of organic matter and improved resistance against pests and diseases

in risk stratification of subjectscan contributein risk stratification of subjects

to slow progression of the diseasemight leadto slow progression of the disease

from microorganisms actively growing in a culture mediumresultingfrom microorganisms actively growing in a culture medium

to disease statescan leadto disease states

to slow progression of the disease and result in the so - called cardiac or renal variants with delayed presentationmight leadto slow progression of the disease and result in the so - called cardiac or renal variants with delayed presentation

in risk stratification of subjects with variant ACADM genotypescan contributein risk stratification of subjects with variant ACADM genotypes

to fatty acidsleadingto fatty acids

in fatigueresultsin fatigue

to an increase in the half - life of calcitriolleadingto an increase in the half - life of calcitriol

to tumor formation and inflammatory digestive , respiratory , and cardiovascular conditionsleadsto tumor formation and inflammatory digestive , respiratory , and cardiovascular conditions

to the deterioration of foods qualitycan leadto the deterioration of foods quality

to accumulation of heparan sulfate ( HS ... in the brain and other organs as well as progressive brain atrophy with cortical gray matter volume lossleadsto accumulation of heparan sulfate ( HS ... in the brain and other organs as well as progressive brain atrophy with cortical gray matter volume loss

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