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Their incorporation into the DNAmay leadto base substitution mutations
agentscausebase substitution mutations
replicationwould causebase substitution mutations
the major adductdid ... causebase substitution mutations
Some analogs may be incorporated into nucleic acids in place of the normal baseoften resultingin a base substitution mutation
Single nucleotide polymorphism ( SNPresultsfrom a base substitution mutation
diseasecausingreplacement mutations
a mistake in the DNAcan causevariation mutation
the substitution of one nucleotide with another ( such as the substitution of a T for a C).(passive) are caused by Substitution mutations
errorsresultfrom substitution mutations
replicationleadingto substitution mutations
Chemical mutagensusually causesubstitution mutations
by chemicals or malfunction of DNA replication(passive) often caused bySubstitution mutations
by Cas9(passive) caused bysubstitution mutations
Abou Jamra R.leadsMAN1B1 mutation
a codon mutationresultsin a substitution mutation of a
substitution mutationsresultsin substitution mutation
the most common diseasecausingCFTR mutation
the possible changescan resultfrom a substitution mutation
a number of sources directly related to the reading and storage of DNA(passive) can be caused byA substitution mutation
a base analogcan causea substitution mutation
or thymineresultingin a substitution mutation
by Cas9(passive) caused bysubstitution mutation
these internal driverscan causea substitution mutation
to be 1 of 300 in the US with her diseasecausingCRB1 mutation
a novel Leigh syndromecausingNDUFS3 mutation
A mousecausesMecp2-null mutation
Particularly want to talk about the most unusual roses : floribunda Masquerade ( floribunda ) and Masquerade Climbing ( climbingresultingpochkovoy mutation
However , this binding to DNA will cause replication errors in living tissuepossibly leadingto mutation Mutation
by irradiation(passive) caused bygermline mutation
background radiation at additional doses below 100mSv(passive) caused byoncogene mutation
the X - Gene in the mutants ' DNA(passive) is caused byMutation Mutation
their endonuclease sitescan causedeleterious mutation
replication errors in living tissuepossibly leadingto mutation Mutation
an amino acid replacementcausesan amino acid replacement
the replacement of a single base nucleotide with another nucleotidecausesthe replacement of a single base nucleotide with another nucleotide
The blood disease Sickle - cell anemia(passive) is caused byThe blood disease Sickle - cell anemia
the replacement of a single base nucleotide with another nucleotidecausesthe replacement of a single base nucleotide with another nucleotide
in the amino acid substitutionresultsin the amino acid substitution
Sickle cell anemia(passive) is caused bySickle cell anemia
the replacement of a single base nucleotide with another nucleotide in DNAcausesthe replacement of a single base nucleotide with another nucleotide in DNA
a difference in the proteinmay causea difference in the protein
the replacement of single base nucleotide with another nucleotidecausesthe replacement of single base nucleotide with another nucleotide
in the alteration of a single amino acidresultsin the alteration of a single amino acid
an amino acid to be inserted which differs from that in a wild - type proteincausesan amino acid to be inserted which differs from that in a wild - type protein
the same amino acid to be inserted as was found in wild - typecausesthe same amino acid to be inserted as was found in wild - type
changes at the translational levelcausingchanges at the translational level
an amino acid to be inserted at that codon that differs from that in the wild typecausesan amino acid to be inserted at that codon that differs from that in the wild type
E.do ... leadE.
premature stopcausespremature stop
to changes in the amino acid sequence of a proteinleadto changes in the amino acid sequence of a protein
to amino acid change affecting enzyme functionleadingto amino acid change affecting enzyme function
no amino acid changecausesno amino acid change
no amino acid changecausesno amino acid change
to biological changescan leadto biological changes
in a different amino acid being placed at a specific position in a proteinresultin a different amino acid being placed at a specific position in a protein
multiple amino acid changesmay causemultiple amino acid changes
in a different amino acid being placed at a specific position in a protein , causing small changesresultin a different amino acid being placed at a specific position in a protein , causing small changes
in premature terminationcan resultin premature termination
PEPR - regulated genes(passive) was influenced byPEPR - regulated genes
a frame shiftcan causea frame shift
Another disease(passive) caused byAnother disease
Another disease(passive) caused byAnother disease
many other disease(passive) caused bymany other disease
a difference in the proteinmay causea difference in the protein
to a missense mutationleadingto a missense mutation
in a termination codonresultingin a termination codon
in mepA overexpressionmay resultin mepA overexpression
it to produce cancercausesit to produce cancer
in the development of late - onset PDresultsin the development of late - onset PD
in a novel methionineresultingin a novel methionine
mRNA Sickle - cell disease(passive) is caused bymRNA Sickle - cell disease
sickle - cell anemiacausessickle - cell anemia
sickle cell anemia(passive) caused bysickle cell anemia