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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

Factorsinfluencingchitosan 's solubility

moleculesresultingin increased solubility

featuresresultin increased solubility

to form amorphous solid dispersions of poorly soluble drugs ,resultingin increased solubility

when equilibrium is again establishedresultingin increased solubility

This combination of persistence ( over months or years ) andhas ledsolubility in water

This combination of persistence ( over months or years ) andleadssolubility in water

by the rigid backbone(passive) caused bypoor solubility

the hydrationresultsin fine solubility

a groupcontributingtoward solubility

a methyl group or the likecontributingtoward solubility

The electronic properties obtained ... believedto contributeto compound solubility

potential drugsmay influencecystine solubility

the phenolic hydroxylscontributedto the solubility of lignin

the factorsinfluencingsolubility of solids

Factors derived from other connective tissues such as plasma and synovial fluidalso influencedurate solubility

the increased osmotic pressureinfluencingsolubility of erythropoietin

the following reactions(passive) is influenced bythe solubility of AgCl

Also , since the pH is very much higher than the pKa values of carboxylic acids , any of those groups also will be in their dissociated , charged formthus contributingto the solubility

the temperature of the solution(passive) is influenced bySolubility

The presence of other solutes in the solventcan also influencesolubility

multiple proteinscontributingto curcuminoid solubility

These acetyl groupscontributeto the solubility

groupscontributeto the solubility

the addition of fairly high concentration of alkali metal salts of various organic acids ( Neuberg , 1916(passive) caused bysolubility

other salts(passive) caused bysolubility

The decreasecausesin solubility

This hydrophilic C - terminusmay contributeto the solubility of LipL41

polymer molecular weightcan influencesolubility

Variationscan leadin solubility

The abilityto influencesolubility

other factors , including the method of serum preparation or as yet unidentified individual or species - specific differences in serum compositioncontributeto curcuminoid solubility

by reduced acid secretion in the stomach caused by PPIs(passive) caused bymycophenolate mofetil solubility

the only parameterinfluencedsolubility

those chargescontributeto the solubility

to solve that problem with the usage of thermocleavable sidechainsleadingto a switchable solubility

the important factorsinfluencingsolubility

t cleavage of just a few bondscan resultin solubility

This leads to increased polarityresultingin solubility

accumulation ... sandwill resultin solubility

stability and detectionresultedstability and detection

in low bioavailabilityresultsin low bioavailability

in low bioavailability after aloneresultsin low bioavailability after alone

in bioavailability problems that put them in class 2 of the Biopharmaceutical Classification System ( BCSresultingin bioavailability problems that put them in class 2 of the Biopharmaceutical Classification System ( BCS

to development of more soluble semi - synthetic derivativesledto development of more soluble semi - synthetic derivatives

in the generation of misleading or inaccurate data , result in project delays and ultimately increase the overall cost of a projectcan resultin the generation of misleading or inaccurate data , result in project delays and ultimately increase the overall cost of a project

oftencausesoften

to limited systemic exposure of oral drugsusually leadsto limited systemic exposure of oral drugs

to lower absorption , poor bioavailabilityleadsto lower absorption , poor bioavailability

low bioavailability ( the degree and rate at which a drug is absorbed into the bodycauseslow bioavailability ( the degree and rate at which a drug is absorbed into the body

to a low bioavailabilityleadsto a low bioavailability

to variable oral bioavailability or drug precipitationleadsto variable oral bioavailability or drug precipitation

in poor dissolution and bioavailabilityresultsin poor dissolution and bioavailability

to poor dissolution and bioavailabilityleadsto poor dissolution and bioavailability

in poor dissolution and bioavailabilityresultsin poor dissolution and bioavailability

to poor bioavailabilityleadsto poor bioavailability

low bioavailabilitycan causelow bioavailability

to low bioavailabilitycan leadto low bioavailability

to low bioavailability resulting in suboptimal drug deliverycan leadto low bioavailability resulting in suboptimal drug delivery

to variable oral bioavailability or drug precipitation following parenteral administrationleadsto variable oral bioavailability or drug precipitation following parenteral administration

to poor absorption in the gastrointestinal tractleadsto poor absorption in the gastrointestinal tract

in limited bioavailabilityresultingin limited bioavailability

low bioavailability and a decreased chance of drug administration resulting positive clinical outcomescauseslow bioavailability and a decreased chance of drug administration resulting positive clinical outcomes

lower PCE(passive) caused bylower PCE

in reduced efficacy and also makes them difficult to developresultsin reduced efficacy and also makes them difficult to develop

to the chemical variations in its waterthus contributingto the chemical variations in its water

crystallization and insufficient sweetness in dairy foodcan causecrystallization and insufficient sweetness in dairy food

if dissolved in an aqueous medium , when they were in a form of a solid preparationcausedif dissolved in an aqueous medium , when they were in a form of a solid preparation

to the chemical variations in its waterthus contributingto the chemical variations in its water

to quantitative differences in MGIT 960 versus 7H10 agar dilution - based DST ( Table 1 and Fig . 1ledto quantitative differences in MGIT 960 versus 7H10 agar dilution - based DST ( Table 1 and Fig . 1

even more useful tipswill discovereven more useful tips

to enhanced bioavailability through oral administrationmay leadto enhanced bioavailability through oral administration

to compromised cytoprotectionleadingto compromised cytoprotection

to precipitation of mineral saltsleadto precipitation of mineral salts

disease andhas ... may causedisease and

The preferred location of the compression component 16(passive) is influenced byThe preferred location of the compression component 16

in high dissolution rate and bioavailability of this essentially poorly water soluble drug LMNresultingin high dissolution rate and bioavailability of this essentially poorly water soluble drug LMN

the robot to exhibit alternating flight phases and stance phasescausingthe robot to exhibit alternating flight phases and stance phases

in a new precipitateresultingin a new precipitate

in aggregation and/or larger particle sizeresultingin aggregation and/or larger particle size

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Smart Reasoning:

C&E

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