to form amorphous solid dispersions of poorly soluble drugs ,resultingin increased solubility
when equilibrium is again establishedresultingin increased solubility
This combination of persistence ( over months or years ) andhas ledsolubility in water
This combination of persistence ( over months or years ) andleadssolubility in water
by the rigid backbone(passive) caused bypoor solubility
the hydrationresultsin fine solubility
a groupcontributingtoward solubility
a methyl group or the likecontributingtoward solubility
The electronic properties obtained ... believedto contributeto compound solubility
potential drugsmay influencecystine solubility
the phenolic hydroxylscontributedto the solubility of lignin
the factorsinfluencingsolubility of solids
Factors derived from other connective tissues such as plasma and synovial fluidalso influencedurate solubility
the increased osmotic pressureinfluencingsolubility of erythropoietin
the following reactions(passive) is influenced bythe solubility of AgCl
Also , since the pH is very much higher than the pKa values of carboxylic acids , any of those groups also will be in their dissociated , charged formthus contributingto the solubility
the temperature of the solution(passive) is influenced bySolubility
The presence of other solutes in the solventcan also influencesolubility
the addition of fairly high concentration of alkali metal salts of various organic acids ( Neuberg , 1916(passive) caused bysolubility
other salts(passive) caused bysolubility
The decreasecausesin solubility
This hydrophilic C - terminusmay contributeto the solubility of LipL41
polymer molecular weightcan influencesolubility
Variationscan leadin solubility
The abilityto influencesolubility
other factors , including the method of serum preparation or as yet unidentified individual or species - specific differences in serum compositioncontributeto curcuminoid solubility
by reduced acid secretion in the stomach caused by PPIs(passive) caused bymycophenolate mofetil solubility
the only parameterinfluencedsolubility
those chargescontributeto the solubility
to solve that problem with the usage of thermocleavable sidechainsleadingto a switchable solubility
the important factorsinfluencingsolubility
t cleavage of just a few bondscan resultin solubility
This leads to increased polarityresultingin solubility
accumulation ... sandwill resultin solubility
stability and detectionresultedstability and detection
in low bioavailabilityresultsin low bioavailability
in low bioavailability after aloneresultsin low bioavailability after alone
in bioavailability problems that put them in class 2 of the Biopharmaceutical Classification System ( BCSresultingin bioavailability problems that put them in class 2 of the Biopharmaceutical Classification System ( BCS
to development of more soluble semi - synthetic derivativesledto development of more soluble semi - synthetic derivatives
in the generation of misleading or inaccurate data , result in project delays and ultimately increase the overall cost of a projectcan resultin the generation of misleading or inaccurate data , result in project delays and ultimately increase the overall cost of a project
oftencausesoften
to limited systemic exposure of oral drugsusually leadsto limited systemic exposure of oral drugs
low bioavailability ( the degree and rate at which a drug is absorbed into the bodycauseslow bioavailability ( the degree and rate at which a drug is absorbed into the body
to a low bioavailabilityleadsto a low bioavailability
to variable oral bioavailability or drug precipitationleadsto variable oral bioavailability or drug precipitation
in poor dissolution and bioavailabilityresultsin poor dissolution and bioavailability
to poor dissolution and bioavailabilityleadsto poor dissolution and bioavailability
in poor dissolution and bioavailabilityresultsin poor dissolution and bioavailability
to poor bioavailabilityleadsto poor bioavailability
low bioavailabilitycan causelow bioavailability
to low bioavailabilitycan leadto low bioavailability
to low bioavailability resulting in suboptimal drug deliverycan leadto low bioavailability resulting in suboptimal drug delivery
to variable oral bioavailability or drug precipitation following parenteral administrationleadsto variable oral bioavailability or drug precipitation following parenteral administration
to poor absorption in the gastrointestinal tractleadsto poor absorption in the gastrointestinal tract
in limited bioavailabilityresultingin limited bioavailability
low bioavailability and a decreased chance of drug administration resulting positive clinical outcomescauseslow bioavailability and a decreased chance of drug administration resulting positive clinical outcomes
lower PCE(passive) caused bylower PCE
in reduced efficacy and also makes them difficult to developresultsin reduced efficacy and also makes them difficult to develop
to the chemical variations in its waterthus contributingto the chemical variations in its water
crystallization and insufficient sweetness in dairy foodcan causecrystallization and insufficient sweetness in dairy food
if dissolved in an aqueous medium , when they were in a form of a solid preparationcausedif dissolved in an aqueous medium , when they were in a form of a solid preparation
to the chemical variations in its waterthus contributingto the chemical variations in its water
to quantitative differences in MGIT 960 versus 7H10 agar dilution - based DST ( Table 1 and Fig . 1ledto quantitative differences in MGIT 960 versus 7H10 agar dilution - based DST ( Table 1 and Fig . 1
even more useful tipswill discovereven more useful tips
to enhanced bioavailability through oral administrationmay leadto enhanced bioavailability through oral administration
to compromised cytoprotectionleadingto compromised cytoprotection
to precipitation of mineral saltsleadto precipitation of mineral salts
disease andhas ... may causedisease and
The preferred location of the compression component 16(passive) is influenced byThe preferred location of the compression component 16
in high dissolution rate and bioavailability of this essentially poorly water soluble drug LMNresultingin high dissolution rate and bioavailability of this essentially poorly water soluble drug LMN
the robot to exhibit alternating flight phases and stance phasescausingthe robot to exhibit alternating flight phases and stance phases