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Qaagi - Book of Why

Causes

Effects

Since(passive) is causedTreatment for steroid - resistant Nephrotic Syndrome patient

PAX2 mutationsmay causesteroid - resistant nephrotic syndrome and FSGS in children

mutationscausingthe steroid - resistant nephrotic syndrome in children

Nephrin mutationscan causechildhood - onset steroid - resistant nephrotic syndrome

mutations ... 50 genescan leadto monogenic steroid - resistant nephrotic syndrome ( SRNS

Mutations in > 50 genescan leadto monogenic steroid - resistant nephrotic syndrome ( SRNS

50 genescan leadto monogenic steroid - resistant nephrotic syndrome ( SRNS

> 50 genescan leadto monogenic steroid - resistant nephrotic syndrome ( SRNS

a genecausesa phenocopy of steroid - resistant nephrotic syndrome

its mutationscausingrecessive steroid - resistant nephrotic syndrome

cells ... sufficientto causesteroid - refractory disease

by my current medications(passive) caused bysteroid - induced Cushing 's syndrome

by loss - of - function mutations(passive) caused bysteroid - resistant nephrotic syndrome

by minimal change disease(passive) caused bysteroid - dependent nephrotic syndrome

Mutationcausessteroid resistant nephrotic syndrome

the most commonly mutated genecausingsteroid - resistant nephrotic syndrome

componentcausesteroid - resistant nephrotic syndrome

panels of genes ( eg all genes knownto causesteroid resistant nephrotic syndrome

multiple genetic causeshave been discoveredfor steroid resistant nephrotic syndrome

Dominant PAX2 mutationsmay causesteroid - resistant nephrotic syndrome and

new genetic mutationscould leadto steroid - resistant nephrotic syndrome

However , only one gene has till date been shownto monogenetically causesteroid - sensitive nephrotic syndrome

by loss - of - function mutations in sphingosine-1-phosphate lyase ( SGPL1(passive) caused bysteroid - resistant nephrotic syndrome

loss - of - function mutations in sphingosine-1-phosphate lyase ( SGPL1(passive) caused bysteroid - resistant nephrotic syndrome

steroid sulfatase gene mutations(passive) caused bysteroid sulfatase deficiency

elevated , nonsuppressible , ACTH levelsleadingto adrenal steroid hypersecretion

dermal atrophycausingsteroid purpura

a factory in some effectsto causea factory in some effects

some side effects(passive) caused bysome side effects

massive proteinuriacan causemassive proteinuria

negative effectsto causenegative effects

low testosterone levelscauseslow testosterone levels

heart attack and strokecan causeheart attack and stroke

CAH(passive) is most often caused byCAH

lots of side effectsusually causeslots of side effects

gynecomastia(passive) caused bygynecomastia

right into your abnormal veinsetright into your abnormal vein

15 % of chronic kidney disease casescauses15 % of chronic kidney disease cases

15 % of chronic kidney disease casescauses15 % of chronic kidney disease cases

to albuminleadingto albumin

a repeat kidney biopsy(passive) caused bya repeat kidney biopsy

to glaucoma and permanent thinning of already thin skincan leadto glaucoma and permanent thinning of already thin skin

to renal failureleadsto renal failure

several side effectscausesseveral side effects

may to the problems of prostate to ( dhtcausedmay to the problems of prostate to ( dht

severe bladder and secondary renal damagemay indeed causesevere bladder and secondary renal damage

in inferior response rates as compared with those who experienced relapse after steroid treatment ( 55.6 % vs. 91.7 % , p=0.042 ... and the time between diagnosis and surgery is another predictive factor for favorable outcomes ( p=0.049resultedin inferior response rates as compared with those who experienced relapse after steroid treatment ( 55.6 % vs. 91.7 % , p=0.042 ... and the time between diagnosis and surgery is another predictive factor for favorable outcomes ( p=0.049

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Smart Reasoning:

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