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Qaagi - Book of Why

Causes

Effects

salmonellacausesosteomyelitis in sickle cell anemia

Why salmonellacausesosteomyelitis in sickle cell anemia

In humans , a single - base - pair change in the beta - hemoglobin gene changes one amino acid in the beta - hemoglobin proteinresultingin sickle cell anemia

a point mutation in the beta globin gene of hemoglobin(passive) is caused bySickle cell anemia

a mutation in the hemoglobin beta gene ( HBB(passive) is caused bySickle Cell Anemia

a point mutation in the beta hemoglobin gene(passive) is caused bySickle cell anemia

a mutation in the HBB gene which provides the instructions to make part of hemoglobin , the protein in red blood cells that carries oxygen(passive) is caused bySickle cell anemia

a mutation in one of the hemoglobin genes(passive) is caused bySickle cell anemia

a genetic mutation in the beta globin gene of hemoglobin(passive) is caused bySickle cell anemia

a mutation of the HBB gene that produces hemoglobin protein(passive) is caused bySickle cell anemia

a mutation in the HBB gene that provides instructions to make the protein hemoglobin , a molecule inside red blood cells that is responsible for carrying oxygen(passive) is caused bySickle cell anemia

a point mutation in the beta - globin gene ( HBb(passive) is caused bySickle cell anemia

a single base mutation in the DNA code for hemoglobincan resultin sickle cell anemia

a mutation in the beta - globin gene , HBB(passive) is caused bySickle cell anemia

a single recessive allele , which produces abnormal hemoglobin the protein that carries oxygen in red blood cells(passive) is caused bySickle cell anemia

by a single mutation in the human beta globin gene(passive) is caused bysickle cell anemia

by a single mutation in the human beta globin gene(passive) is causedsickle cell anemia

a mutation that alters one amino acid in the protein hemoglobin(passive) is caused bySickle - cell anemia

a point mutation in the hemoglobin gene(passive) is caused bySickle cell anemia

a defect in the gene that controls the production of normal hemoglobin , which is an iron - containing protein in red blood cells that transports oxygen from the lungs to body tissues(passive) is caused bySickle cell anemia

a mutation of the hemoglobin genecausessickle - cell anemia

a mutation in the hemoglobin genecausessickle cell anemia

mutation of the hemoglobin genecan causesickle - cell anemia

a single point mutation in the hemoglobin gene that results in a faulty protein(passive) is caused bySickle Cell Anemia

the point mutation in the beta ( ) globin genecausessickle cell anemia

a genecausessickle cell anemia ( in homozygotes

a point mutation in protein chain of hemoglobin(passive) is caused bySickle - cell anemia

the mutation in the beta - globin genecausessickle cell anemia

a mutation ( change ) in one of the genes for hemoglobin ( the substance inside red blood cells that binds to oxygen(passive) is caused bySickle cell anemia

a mutation ( change ) in one of the genes for hemoglobin ( the substance inside red blood cells that binds to oxygen and(passive) is caused bySickle cell anemia

by a single point mutation in the beta - globin chain of hemoglobin(passive) is caused bySickle cell anemia

the point mutation ... the beta - hemoglobin chaincausessickle cell anemia

the point mutation to the beta - hemoglobin chaincausessickle cell anemia

a mutation ( an abnormal change ) in the gene that instructs the body to produce hemoglobin(passive) is caused bySickle cell anemia

The mutation ... the hemoglobin beta chainresultsin sickle - cell anemia

a point mutation on the DNA of the beta - globin chain(passive) is caused bySickle cell anemia

an error in a gene that makes the beta globin chain of hemoglobin(passive) is caused bySickle cell anemia

a genetic mutation ... a single amino acid substitution in the hemoglobin moleculecausessickle cell anemia

by a mutation in the gene encoding for hemoglobin , which is the protein in red blood cells that carries oxygen(passive) is caused bySickle cell anemia

a mutation in the gene encoding for hemoglobin , which is the protein in red blood cells that carries oxygen(passive) is caused bySickle cell anemia

the bone marrow to produce misshapen , sickle - shaped red blood cellscausesthe bone marrow to produce misshapen , sickle - shaped red blood cells

red blood cells to change shape , losing their ability to hold oxygencausesred blood cells to change shape , losing their ability to hold oxygen

red blood cells to become shaped like crescent moons or sickles and have a sticky , rigid texture , in comparison to healthy red blood cells that are round and flexiblecausesred blood cells to become shaped like crescent moons or sickles and have a sticky , rigid texture , in comparison to healthy red blood cells that are round and flexible

Mitigate health problems(passive) caused byMitigate health problems

gallstonesdoes ... causegallstones

The disease(passive) is causedThe disease

sickle - shaped red blood cellscausessickle - shaped red blood cells

red blood cells to form an abnormal crescent shape due to an abnormal form of hemoglobincausesred blood cells to form an abnormal crescent shape due to an abnormal form of hemoglobin

to its pathophysiology and phenotypic variabilitycontributesto its pathophysiology and phenotypic variability

the red blood cells to be malformed ( crescent moon or sickle - shaped ) , sticky and rigidcausesthe red blood cells to be malformed ( crescent moon or sickle - shaped ) , sticky and rigid

red blood cells to form an abnormal crescent shapecausesred blood cells to form an abnormal crescent shape

complications(passive) caused bycomplications

early destruction of red cellscausesearly destruction of red cells

alsocan ... leadalso

severe paincausessevere pain

sickle - shaped red blood cellscausessickle - shaped red blood cells

a multitude of symptoms to manifest , one of which is paincan causea multitude of symptoms to manifest , one of which is pain

pneumonia(passive) caused bypneumonia

skin ulcers in the legscausesskin ulcers in the legs

a painful blockage of blood flowcan causea painful blockage of blood flow

in a decrease in perioperative morbidity and mortalitywill resultin a decrease in perioperative morbidity and mortality

abnormally shaped red blood cells , and malariacausesabnormally shaped red blood cells , and malaria

red blood cell to be deformed and sickle shapedcausesred blood cell to be deformed and sickle shaped

in an abnormal protein in red blood cellsresultsin an abnormal protein in red blood cells

in an abnormal _ _ _ _ _ _ _ _ _ _ _ _ protein in red blood cellsresultsin an abnormal _ _ _ _ _ _ _ _ _ _ _ _ protein in red blood cells

red blood cells to carry oxygencausesred blood cells to carry oxygen

periodic episodes of intense paincausesperiodic episodes of intense pain

from an abnormality in the oxygen - carrying protein hemoglobin found in red blood cellsresultsfrom an abnormality in the oxygen - carrying protein hemoglobin found in red blood cells

the equivalent of 5 % of underfive deaths in Africacontributesthe equivalent of 5 % of underfive deaths in Africa

the red blood cells in take a sickle type shape instead of the normal round shapecausesthe red blood cells in take a sickle type shape instead of the normal round shape

in severe pain , organ damage and deathcan resultin severe pain , organ damage and death

the production of abnormal hemoglobincausesthe production of abnormal hemoglobin

blood cells to clump up and block blood vesselscan causeblood cells to clump up and block blood vessels

blood cells to clump up and block blood vesselscan causeblood cells to clump up and block blood vessels

blood cells to clump up and block blood vesselsmight causeblood cells to clump up and block blood vessels

blood cells to clump up & block blood vesselscan causeblood cells to clump up & block blood vessels

red blood cells to be shaped like sicklescausered blood cells to be shaped like sickles

such damage to his hip that he now needs a crutch to walkhas causedsuch damage to his hip that he now needs a crutch to walk

episodes of severe paincan causeepisodes of severe pain

brain ischemia associated with the irregularly shaped blood cellsmay causebrain ischemia associated with the irregularly shaped blood cells

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