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Qaagi - Book of Why

Causes

Effects

tumor developmentcan causetumor cell death;[36

peripheral areascomposedof an infiltrating , malignant spindle - cell tumor

a potentialto causetumor cell damage[73

other drugscauseSPINDLE CELL SARCOMA

to heardiscoveredthe spindle cell sarcoma

p53 gene activation ... a common wayto causetumor cell apoptosis

inhibition of FAScausestumor cell apoptosis

substancescausetumor cell growth

The architecture of fibroblast monolayers of different origindifferentially influencestumor cell growth

activation of TRPM8can causetumor cell apoptosis

antitumor agentscausingtumor cell apoptosis

components can enhance anti - tumor resistancecausingtumor cell apoptosis

anti - tumor immunitycausingtumor cell apoptosis

of almost exclusively of elongated fusiform cells with cigar - shaped nuclei and prominent nucleoli(passive) is composedSpindle cell rhabdomyosarcoma

Neuroblastomacomposedof fusiform / spindle shaped tumor cells

endotoxin - induced serum factorcausedtumor cell necrosis

Regulation of cell motility ... by whichinfluencestumor cell metastasis

Regulation of cell motility ... by whichinfluencestumor cell metastasis

the tumor microenvironmentcan influencetumor cell dissemination.4

the mechanismscausingtumor cell metastasis

factorsinfluencingtumor cell metastasis

by which topoisomerase inhibitorscausetumor cell cytotoxicity

these effectsdo ... causetumor cell cytotoxicity

integrin activationcan influencetumor cell metastasis

primary tumor growthcould influencetumor cell metastasis

P - GNRs - DOX+laser may be more ablativecausingtumor cell necrosis

CAS / Crk signalingmay ... influencetumor cell metastasis

C ) Fully activated CARs attack target cellscausingtumor cell lysis

therapy with allopurinol ( allopurinol sodium ) for Injection ... knownto causetumor cell lysis

The virus ... tumor cellscausestumor cell lysis

accessory cells formto causetumor cell lysis

In presence of ertumaxomab , tri - cell complexes consisting of tumor cells , T cells , and accessory cells formto causetumor cell lysis

selectively infects and replicates in tumor cellseventually causingtumor cell lysis

an immune responsecausingtumor cell lysis

antigenscausingtumor cell lysis

the cytotoxic granulesmay causetumor cell lysis

levels sufficientto causetumor cell lysis

cellular phenotypeinfluencingtumor cell malignancy

Furthermore , mtDNA dysfunction affecting the electron transport chain can lead to generation of excess reactive oxygen species ( ROScontributingto tumor cell metastasis

MMP9 mediates matrix degradationcausingtumor cell spreading

H&E. The tumor(passive) is composedH&E. The tumor

from smooth muscle cellsoriginatingfrom smooth muscle cells

of ovalcomposedof oval

The type(passive) are composedThe type

from the connective tissue of , or beneath , the skinoriginatefrom the connective tissue of , or beneath , the skin

in the connective tissues of the skin and beneath the skinoriginatein the connective tissues of the skin and beneath the skin

from the connective tissue of , or beneath , the skinoriginatefrom the connective tissue of , or beneath , the skin

of granulosa cellscomposedof granulosa cells

of sertoli cells line each tubulecomposedof sertoli cells line each tubule

of cells parallel to basement membranecomposedof cells parallel to basement membrane

the carcinoid syndromecausingthe carcinoid syndrome

from adrenal medullaoriginatedfrom adrenal medulla

of benign ovarian tumourscomposedof benign ovarian tumours

to elevation of estrogen levelmay leadsto elevation of estrogen level

of densely cellular sheets and fascicles with occasional nuclear palisading ( Figure 2composedof densely cellular sheets and fascicles with occasional nuclear palisading ( Figure 2

of crowded pale glandscomposedof crowded pale glands

of lipids , proteins , and calcic debriscomposedof lipids , proteins , and calcic debris

to a chronic nerve pain conditionledto a chronic nerve pain condition

of sheets , nests , and occasion- ally inammatory cellscomposedof sheets , nests , and occasion- ally inammatory cells

of fibroblast - like cells and histiocyte - like cellscomposedof fibroblast - like cells and histiocyte - like cells

of fibroblast - like cells and histiocyte - like cells with a collagenous matrixcomposedof fibroblast - like cells and histiocyte - like cells with a collagenous matrix

of tubules lined by a second anti - tnf if there is little evidence that they are not metcomposedof tubules lined by a second anti - tnf if there is little evidence that they are not met

of syncytiotro- phoblast , cytotrophoblast , and intermediate riskcomposedof syncytiotro- phoblast , cytotrophoblast , and intermediate risk

massive release of inflammatory mediatorscan causemassive release of inflammatory mediators

in vitroleadsin vitro

Skin Cancer in Dogs BreakthroughCausesSkin Cancer in Dogs Breakthrough

from a primary tumororiginatefrom a primary tumor

in increased tumor volume in LLresultedin increased tumor volume in LL

in improved drug deliveryresultingin improved drug delivery

to LRR primarilyleadingto LRR primarily

to metastatic invasion that causes the vast majority of cancer deathscontributesto metastatic invasion that causes the vast majority of cancer deaths

in distant metastases [ 23 , 24resultsin distant metastases [ 23 , 24

to efficient virus replication and consequent cancer specific cytotoxicityleadsto efficient virus replication and consequent cancer specific cytotoxicity

a dilution of tumor cell - specific imbalancescausinga dilution of tumor cell - specific imbalances

to inactivation of Akt and extracellular signal - regulated kinase ( ERK ) signaling as well as induction of the TRAIL pathwayleadingto inactivation of Akt and extracellular signal - regulated kinase ( ERK ) signaling as well as induction of the TRAIL pathway

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