smoking or environmental factors(passive) can be caused bySomatic mutations
indels ( insertions or deletions(passive) are caused byFrameshift mutations
lifestyle and environmental factors(passive) influenced bysomatic mutations
environmental factors , such as exposure to ultraviolet radiation or to certain chemicals(passive) are frequently caused bySomatic mutations
point mutations or small insertions / deletionscausingframeshift mutations
environmental factors , such as cigarette smoke(passive) can sometimes be caused bySomatic mutations
small deletions and insertions(passive) caused byframeshift mutations
a number of different environmental factors(passive) can be caused bySomatic mutations
environmental factors – meaning , not inherited(passive) are ... caused bysomatic mutations
insertions or deletions of a nucleotide(passive) are caused byFrameshift mutations
6 Insertions and deletionscauseframeshift mutations
eithersmall insertions or deletions(passive) caused byframeshift mutations
insertions or deletions of base pairscauseframeshift mutations
The majority of human cancers ... environmental factors and carcinogenic agentsmay leadto somatic mutations
environmental factors such as exposure to ultraviolet radiation , etc(passive) are also caused bySomatic mutations
insertions or deletions of nucleotides and point mutations(passive) caused byframeshift mutations
Insertions , deletions or duplications of a few base pairscauseframeshift mutations
insertions or deletions of a number of nucleotides that are not a multiple of three(passive) caused byframeshift mutations
small insertions and deletions ( indels ) in proteins that are expressed and properly processed by the antigen presentation machinery , culminating in the exposure of tumor neoantigens ( TNAs(passive) caused byframeshift mutations
Carey , exposure to ultraviolet wavelengths in sunlight , or to cancer - causing chemicalscan causesomatic mutations
insertion or deletion of ≥1 nucleic acids in the coding region often resulting in shortened truncated proteins ( frequently found in the MYBPC gene ) , or abnormal splicing of messenger ribonucleic acid ( mRNA(passive) are caused byFrameshift mutations
Non - homologous end joining ( NHEJ ... random insertions or deletionsmay causeframeshift mutations
SSRs(passive) caused byframeshift mutations
when there are insertions , deletions and duplication of the DNA bases in a gene(passive) are also causedFrameshift mutations
single base - pair deletions(passive) caused byframeshift mutations
exon 9 deletions or insertions(passive) caused byframeshift mutations
environmental and life - style factorstriggeringsomatic mutations
Cancer - Specific Biomarkers - Altered protein productsresultingfrom somatic mutations
the identification of messenger RNA ... the Crick , Brenner et al . experiment of 1961discoveredframeshift mutations
reveals three factorsresultingfrom somatic mutations
insertions or deletions in the homopolymer guanosine ( G ) and cytidine ( C ) repeat regions of the UL23 gene(passive) caused byFrameshift mutations
radiation damage to DNA(passive) caused bySomatic mutation
DNA damage and copying errors in the genes of tumour cells(passive) are caused bySomatic mutations
a. A point mutation c. A deletion e. A proofreading mutation C : Insertions and deletionscauseframeshift mutations
experiment of 1961,[27discoveredframeshift mutations
experiment of 1961,[26discoveredframeshift mutations
to tissue mosaicismleadto tissue mosaicism
Most breast cancers(passive) are caused byMost breast cancers
in genetic mosaicism.[1][2][3resultin genetic mosaicism.[1][2][3
All cancers are known(passive) to be caused byAll cancers are known
AbstractAll cancers(passive) are caused byAbstractAll cancers
N All cancers(passive) are caused byN All cancers
UK.All cancers(passive) are caused byUK.All cancers
othersNature2013All cancers(passive) are caused byothersNature2013All cancers
to aging and diseases , such as cancerleadingto aging and diseases , such as cancer
to tumorigenesis or malignant transformationcontributeto tumorigenesis or malignant transformation
to Nrf2 accumulation in cancersleadingto Nrf2 accumulation in cancers
in gains of function in human cancersresultingin gains of function in human cancers
cancer or other diseasescan causecancer or other diseases
26195574 Luks VL , Kamitaki N , Vivero MP , Uller W , Rab R , Bovée JV , Rialon KL , Guevara CJ , Alomari AI , Greene AK , Fishman SJ , Kozakewich HP , Maclellan RA , Mulliken JB , Rahbar R , Spencer SA , Trenor CC 3rd , Upton J , Zurakowski D , Perkins JA , Kirsh A , Bennett JT , Dobyns WB , Kurek KC , Warman ML , McCarroll SA , Murillo R. Lymphatic and other vascular malformative / overgrowth disorders(passive) are caused by26195574 Luks VL , Kamitaki N , Vivero MP , Uller W , Rab R , Bovée JV , Rialon KL , Guevara CJ , Alomari AI , Greene AK , Fishman SJ , Kozakewich HP , Maclellan RA , Mulliken JB , Rahbar R , Spencer SA , Trenor CC 3rd , Upton J , Zurakowski D , Perkins JA , Kirsh A , Bennett JT , Dobyns WB , Kurek KC , Warman ML , McCarroll SA , Murillo R. Lymphatic and other vascular malformative / overgrowth disorders
to complete durable regression in metastatic breast cancer Nikolaos Zacharakisleadingto complete durable regression in metastatic breast cancer Nikolaos Zacharakis
disease , including cancercan causedisease , including cancer
to a range of neurodevelopmental and neurodegenerative diseasescontributeto a range of neurodevelopmental and neurodegenerative diseases
most cases of breast cancercausemost cases of breast cancer
The great majority ( > 95 % ) of human cancers(passive) are caused byThe great majority ( > 95 % ) of human cancers
to genotypic diversity in sterile and fertile populations of the threatened shrub , Grevillea rhizomatosa ( Proteaceae ) 28contributeto genotypic diversity in sterile and fertile populations of the threatened shrub , Grevillea rhizomatosa ( Proteaceae ) 28
to genotypic diversity in sterile and fertile populations of the threatened shrub , Grevillea rhizomatosa ( Proteaceae ) 15contributeto genotypic diversity in sterile and fertile populations of the threatened shrub , Grevillea rhizomatosa ( Proteaceae ) 15
to pituitary tumorigenesisleadto pituitary tumorigenesis
to CaP tumorigenesiscontributeto CaP tumorigenesis
to complete durable regression in metastatic breast cancer | Nature Medicine Nikolaos Zacharakis1leadingto complete durable regression in metastatic breast cancer | Nature Medicine Nikolaos Zacharakis1
to complete durable regression in metastatic breast cancer MEDICINE , RESEARCH & EXPERIMENTAL | TCR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMORleadingto complete durable regression in metastatic breast cancer MEDICINE , RESEARCH & EXPERIMENTAL | TCR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR
to breast cancer ( 78leadingto breast cancer ( 78
to the manifestations of the diseaseleadto the manifestations of the disease
to the pathogenesis of the diseasecontributingto the pathogenesis of the disease
to a disease statemay contributeto a disease state
in mosaicism confined to keratinocytes of the affected arearesultingin mosaicism confined to keratinocytes of the affected area
adult - onset disease , such as cancermay causeadult - onset disease , such as cancer
predisposition to multiple sporadic cancerscausingpredisposition to multiple sporadic cancers
sporadic cancers , one of the three kinds of cancercausessporadic cancers , one of the three kinds of cancer
to cancer developmentcould ... contributeto cancer development
to malignancies such as cancerleadingto malignancies such as cancer
to the development of cancerleadto the development of cancer
endometrial cancercausingendometrial cancer
A majority of cancers ... the likelihood that this will happen increases when we get older(passive) are caused byA majority of cancers ... the likelihood that this will happen increases when we get older
to truncations of its protein in many types of tumors , including breast cancer ( 16–24leadto truncations of its protein in many types of tumors , including breast cancer ( 16–24
cancer , possibly other diseases and agingcausecancer , possibly other diseases and aging