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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

C - terminal truncating TREX1 mutations(passive) caused bya monogenic small vessel disease

chronic hypertension and other vascular risk factors(passive) caused bysmall vessel occlusive disease

small - vessel redness usuallyaffects the glomeruli , as delineated in the next incision andon gabapentin titration uk attendant 516(passive) caused bySmall - vessel vasculitisrenal disease

diabetes or hypertension(passive) caused bysmall vessel disease

exactly howcausesmall vessel disease

ischemic stroke in their study(passive) caused bysmall vessel disease

damage to the lining of the tiny blood vessels in the brain which stops them from functioning normally and can cause damage to the brain(passive) is caused bySmall vessel disease

because diabetes tendsto causesmall vessel disease

events and processes other than ischemic stroke(passive) caused bysmall - vessel disease

chronic hypoperfusion as the mechanism of cognitive impairment(passive) caused bysmall vessel disease

stereotyped mutations in the Notch3 gene altering the number of cysteine residues(passive) caused bya cerebrovascular small - vessel disease

by treating the multiple factors leading to small vessel disease(passive) can be preventedSmall vessel disease

risk factors for vascular disease such as smoking , diabetes , high blood pressure and elevated cholesterolcontributeto small vessel disease

In addition , co - morbidities associated with stroke ( e.g. , hypertension , diabetes , history of smoking ) have been suggestedto contributeto small - vessel disease

successive tiny strokes from high blood pressure or diabetes(passive) caused bysmall vessel disease

arterisclerosis of small penetrating vessels within the basal ganglia or pons a. often associated with hypertension or diabetes mellitus b. resulting small infarcts(passive) usually caused bySmall vessel disease

a narrowing of these tiny arteries(passive) is caused bySmall vessel disease

vessel wall abnormalities(passive) caused bySmall vessel diseases

small arteriesleadingto small vessel disease

small - vessel vasculitis usuallyaffects the glomeruli(passive) caused bySmall - vessel vasculitisrenal illness

injection which reduces the individual(passive) caused bysmall vessel disease

chronic exposure of vascular components(passive) is caused bySmall vessel disease

disease of the very small blood vessels that lie deep in the brain(passive) is caused bySmall vessel disease

A narrowing of your heart arteriesleadsto small vessel disease

Plaque buildupmay contributeto small vessel disease

high pressure fluctuationscausingsmall vessel disease

vascular deposits of Aß - amyloid peptides in the walls of cortical and leptomeningeal vessels(passive) caused bya small vessel disease

Cerebral white matter lesions ( WML ) are thoughtto resultfrom small vessel disease

damage to the brain 's white matter(passive) is caused bySmall ischemic vessel disease

endovascular infection , inflammation , and hypercoagulability(passive) caused bysmall vessel disease

mutation NOTCH3 gene on chromosome 19q122(passive) caused bysmall vessel arterial disease

The best wayto preventsmall vessel disease

small strokes caused by my benign heart arryhthmias(passive) caused bysmall vessel ischemic disease

less oxygen ... casescausessmall vessel disease

a cysteine - altering pathogenic variant in one of the 34 epidermal growth factor - like repeat ( EGFr ) domains of the NOTCH3 protein(passive) caused bya small - vessel disease

high cholesterol ( 230 totalCan ... causesmall vessel disease

microscopic brain lesionsresultingfrom small vessel disease

Diagnostic tests could includePreventingsmall vessel disease

small - vessel rubor usuallyaffects the glomeruli(passive) caused bySmall - vessel vasculitisrenal disease

many conditionscausingsmall vessel diseases

dementia or strokemay causedementia or stroke

Lacunar stroke(passive) caused byLacunar stroke

common ischemic stroke(passive) caused bycommon ischemic stroke

a minor stroke(passive) is caused bya minor stroke

in to stroke.[2leadin to stroke.[2

to the pathophysiology of strokecontributesto the pathophysiology of stroke

this sort of strokecan also causethis sort of stroke

Wake - up stroke(passive) to be caused byWake - up stroke

to ischemic stroke and vascular dementialeadingto ischemic stroke and vascular dementia

from one type of strokeresultingfrom one type of stroke

to 20 % of ischemic stroke casesleadsto 20 % of ischemic stroke cases

acute stroke syndromes(passive) caused byacute stroke syndromes

patients with ischaemic stroke(passive) caused bypatients with ischaemic stroke

to awful conditions such as stroke and dementiacan leadto awful conditions such as stroke and dementia

an affiliation amongst NO2 and stroke(passive) triggered byan affiliation amongst NO2 and stroke

a sense of anxiety and concern due to the increased risk of strokecan createa sense of anxiety and concern due to the increased risk of stroke

stroke but is also a major contributor to dementia risk , and is associated with gait problems and depressioncausesstroke but is also a major contributor to dementia risk , and is associated with gait problems and depression

stroke and dementia ... but the trouble is we do n’t know exactly what causes the disease in these small blood vessels in the braincan causestroke and dementia ... but the trouble is we do n’t know exactly what causes the disease in these small blood vessels in the brain

lacunar strokes can also lead to dementiamay causelacunar strokes can also lead to dementia

carotid siphon ( CS ) calcification and lacunar infarction(passive) caused bycarotid siphon ( CS ) calcification and lacunar infarction

to lacunar infarcts and subcortical white matter changesleadingto lacunar infarcts and subcortical white matter changes

a subcortical or lacunar infarct(passive) caused bya subcortical or lacunar infarct

a quarter of ischaemic strokes ( lacunar subtypecausesa quarter of ischaemic strokes ( lacunar subtype

signs and symptoms of heart disease , such as chest pain ( anginacausessigns and symptoms of heart disease , such as chest pain ( angina

Thrombotic strokes(passive) caused byThrombotic strokes

whites of strokes(passive) caused bywhites of strokes

micro infarcts known as ‘ lacunar infarctscausesmicro infarcts known as ‘ lacunar infarcts

20 % of all strokes and is the most common cause of vascular dementiacauses20 % of all strokes and is the most common cause of vascular dementia

more gradual symptomsmay causemore gradual symptoms

in multiple lacunar strokes , leukoaraiosis ( Binswanger ’s diseaseresultsin multiple lacunar strokes , leukoaraiosis ( Binswanger ’s disease

to what doctors call vascular dementiacan leadto what doctors call vascular dementia

NOMASS).34 Among the 195 patients who presented with a lacunar syndrome ( diagnosed within 1 week after stroke onset ) and had a lacunar infarct on CT or MRI , 147 ( positive predictive value=75 %(passive) were caused byNOMASS).34 Among the 195 patients who presented with a lacunar syndrome ( diagnosed within 1 week after stroke onset ) and had a lacunar infarct on CT or MRI , 147 ( positive predictive value=75 %

signs and symptoms of heart disease , such as chest pain and shortness of breathcausessigns and symptoms of heart disease , such as chest pain and shortness of breath

subcortical dementiacausingsubcortical dementia

atrophycausedatrophy

to lacunar infarcts and ischemic white matter changesleadingto lacunar infarcts and ischemic white matter changes

to ischemic lacunar infarction and intracerebral hemorrhageleadingto ischemic lacunar infarction and intracerebral hemorrhage

to lacunar strokes • Can worsen over 1 - 2 days ( stuttering lacuneleadsto lacunar strokes • Can worsen over 1 - 2 days ( stuttering lacune

Lacunar strokes ... an intrinsic disease of the small deep perforating arteries(passive) are caused byLacunar strokes ... an intrinsic disease of the small deep perforating arteries

diabetic retinopathy represents an increased risk of heart failure that is independent of known risk factors [ 13causesdiabetic retinopathy represents an increased risk of heart failure that is independent of known risk factors [ 13

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Smart Reasoning:

C&E

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