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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island – an island also known as “ Rapa Nui ” , hence the name(passive) was first discoveredSirolimus

in soil samples from Easter Island ( Rapa Nui(passive) was discoveredSirolimus

Brazilian researchers in a soil sample from Easter Island,[1 ] also known as Rapa Nui.[2(passive) was discovered bySirolimus

from a soil sample collected in Rapa Nui , which is also known as Easter Island [ 1(passive) was discoveredSirolimus

first(passive) was ... discoveredSirolimus

The administration of donor specific bone marrow ( DSBM ) to mice conditioned with antilymphocyte serum ( ALS ) andcan resultsirolimus

in 1974(passive) was discoveredSirolimus

to stop the growth of blood vessels in the macula(passive) is designedSirolimus

in 1975(passive) was discoveredSirolimus

your blood concentration of sirolimus ... therapeutic … Full Answerdiscoveredsirolimus

to block a protein called mTOR ( a protein that is thought to cause(passive) is designedSirolimus

Additional studieshave discoveredsirolimus

Ultra - short coursecontributessirolimus

side effects in some peoplecan causeside effects in some people

dermal side effects(passive) caused bydermal side effects

side - effects not listed heremay also causeside - effects not listed here

some additional unwanted side effectscan ... causesome additional unwanted side effects

serious side effects or death in patients who have had liver or lung transplantsmay causeserious side effects or death in patients who have had liver or lung transplants

side effects and adverse reactions and is associated with an increased risk of infection and the development of lymphoma and skin cancermay causeside effects and adverse reactions and is associated with an increased risk of infection and the development of lymphoma and skin cancer

life - threatening side effects , or even deathmay causelife - threatening side effects , or even death

several potential side effects that can be very serious , including kidney problemscan causeseveral potential side effects that can be very serious , including kidney problems

to a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p   =   0.04 ) at affected sitesledto a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p   =   0.04 ) at affected sites

side effects such as elevated levels of cholesterol and triglycerides in the bloodcan causeside effects such as elevated levels of cholesterol and triglycerides in the blood

mouth ulcers , sometimes peripheral edema , and gastrointestinal side effectscausesmouth ulcers , sometimes peripheral edema , and gastrointestinal side effects

fetal harm when administered to a pregnant woman ... see Data , Clinical Pharmacology ( 12.1can causefetal harm when administered to a pregnant woman ... see Data , Clinical Pharmacology ( 12.1

potentially fatal complications following transplantationcan causepotentially fatal complications following transplantation

a mild rash that is usually not seriouscan commonly causea mild rash that is usually not serious

side effects such as backache , diarrhea , blurred vision , joint pain , shaking , dry mouth , and runny nosecan causeside effects such as backache , diarrhea , blurred vision , joint pain , shaking , dry mouth , and runny nose

to a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p\u2009=\u20090.04 ) at affected sitesledto a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p\u2009=\u20090.04 ) at affected sites

severe hyperlipidemiacausessevere hyperlipidemia

both proliferation and migration of smooth muscle cells ( in vivo and in vitropreventsboth proliferation and migration of smooth muscle cells ( in vivo and in vitro

organ rejection ( Rapamune ) Document ID 1492to preventorgan rejection ( Rapamune ) Document ID 1492

organ rejection ... Rapamune | Patient - high-kick.ruto preventorgan rejection ... Rapamune | Patient - high-kick.ru

hyperlipidemia , leukopenia , ulcersmay causehyperlipidemia , leukopenia , ulcers

hypertriglyceridemia and hypercholesterolemia ... but it does not increase the incidence of MI or other CVDscauseshypertriglyceridemia and hypercholesterolemia ... but it does not increase the incidence of MI or other CVDs

hyperlipidemia and influence hematological indicatorscan causehyperlipidemia and influence hematological indicators

organ rejection - Rapamune | Patient Sirolimus to prevent organ rejection Rapamune Authored by Michael Stewartto preventorgan rejection - Rapamune | Patient Sirolimus to prevent organ rejection Rapamune Authored by Michael Stewart

progression from the G1 phase ( cell growth ) to the S phase ( DNA replication ... resulting in inhibition of the growth of vascular smooth muscle cells , which is a major process of in - stent restenosispreventsprogression from the G1 phase ( cell growth ) to the S phase ( DNA replication ... resulting in inhibition of the growth of vascular smooth muscle cells , which is a major process of in - stent restenosis

graft failure in patients with renal transplantation for antiphospholipid syndromemay preventgraft failure in patients with renal transplantation for antiphospholipid syndrome

in stable multilineage mixed chimerism and long - term graft survivalcan resultin stable multilineage mixed chimerism and long - term graft survival

hyperlipidemia and has also been associated with hepatic artery thrombosis in liver transplant recipientsmay causehyperlipidemia and has also been associated with hepatic artery thrombosis in liver transplant recipients

an elevation of serum lipidscan causean elevation of serum lipids

the translation of proteins that promote cell survival and proliferation by engaging with FK506-binding protein ( FKBPpreventsthe translation of proteins that promote cell survival and proliferation by engaging with FK506-binding protein ( FKBP

cells from progressing from G1 to the S phasepreventscells from progressing from G1 to the S phase

less nephrotoxicity , neurotoxicity , and hypertensioncausesless nephrotoxicity , neurotoxicity , and hypertension

for increased lipophilicitydesignedfor increased lipophilicity

an increase in serum cholesterol and triglyceridesmay causean increase in serum cholesterol and triglycerides

anaemiacan also causeanaemia

the levels of electrolytes such as potassium , sodium , magnesium , chloride , and calcium in the blood to change while taking this medicationmay causethe levels of electrolytes such as potassium , sodium , magnesium , chloride , and calcium in the blood to change while taking this medication

a round higher chance of developing a blood clot , especially fearful when roughly used with cinnarizinecausesa round higher chance of developing a blood clot , especially fearful when roughly used with cinnarizine

mild cholangitis(passive) possibly caused bymild cholangitis

elastin disruptionpreventedelastin disruption

Pneumonitis(passive) caused byPneumonitis

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Smart Reasoning:

C&E

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