as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island – an island also known as “ Rapa Nui ” , hence the name(passive) was first discoveredSirolimus
in soil samples from Easter Island ( Rapa Nui(passive) was discoveredSirolimus
Brazilian researchers in a soil sample from Easter Island,[1 ] also known as Rapa Nui.[2(passive) was discovered bySirolimus
from a soil sample collected in Rapa Nui , which is also known as Easter Island [ 1(passive) was discoveredSirolimus
first(passive) was ... discoveredSirolimus
The administration of donor specific bone marrow ( DSBM ) to mice conditioned with antilymphocyte serum ( ALS ) andcan resultsirolimus
in 1974(passive) was discoveredSirolimus
to stop the growth of blood vessels in the macula(passive) is designedSirolimus
in 1975(passive) was discoveredSirolimus
your blood concentration of sirolimus ... therapeutic … Full Answerdiscoveredsirolimus
to block a protein called mTOR ( a protein that is thought to cause(passive) is designedSirolimus
Additional studieshave discoveredsirolimus
Ultra - short coursecontributessirolimus
side effects in some peoplecan causeside effects in some people
dermal side effects(passive) caused bydermal side effects
side - effects not listed heremay also causeside - effects not listed here
some additional unwanted side effectscan ... causesome additional unwanted side effects
serious side effects or death in patients who have had liver or lung transplantsmay causeserious side effects or death in patients who have had liver or lung transplants
side effects and adverse reactions and is associated with an increased risk of infection and the development of lymphoma and skin cancermay causeside effects and adverse reactions and is associated with an increased risk of infection and the development of lymphoma and skin cancer
life - threatening side effects , or even deathmay causelife - threatening side effects , or even death
several potential side effects that can be very serious , including kidney problemscan causeseveral potential side effects that can be very serious , including kidney problems
to a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p = 0.04 ) at affected sitesledto a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p = 0.04 ) at affected sites
side effects such as elevated levels of cholesterol and triglycerides in the bloodcan causeside effects such as elevated levels of cholesterol and triglycerides in the blood
mouth ulcers , sometimes peripheral edema , and gastrointestinal side effectscausesmouth ulcers , sometimes peripheral edema , and gastrointestinal side effects
fetal harm when administered to a pregnant woman ... see Data , Clinical Pharmacology ( 12.1can causefetal harm when administered to a pregnant woman ... see Data , Clinical Pharmacology ( 12.1
potentially fatal complications following transplantationcan causepotentially fatal complications following transplantation
a mild rash that is usually not seriouscan commonly causea mild rash that is usually not serious
side effects such as backache , diarrhea , blurred vision , joint pain , shaking , dry mouth , and runny nosecan causeside effects such as backache , diarrhea , blurred vision , joint pain , shaking , dry mouth , and runny nose
to a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p\u2009=\u20090.04 ) at affected sitesledto a change in mean percentage total tissue volume of -7.2 % ( SD 16.0 , p\u2009=\u20090.04 ) at affected sites
severe hyperlipidemiacausessevere hyperlipidemia
both proliferation and migration of smooth muscle cells ( in vivo and in vitropreventsboth proliferation and migration of smooth muscle cells ( in vivo and in vitro
organ rejection ( Rapamune ) Document ID 1492to preventorgan rejection ( Rapamune ) Document ID 1492
hypertriglyceridemia and hypercholesterolemia ... but it does not increase the incidence of MI or other CVDscauseshypertriglyceridemia and hypercholesterolemia ... but it does not increase the incidence of MI or other CVDs
hyperlipidemia and influence hematological indicatorscan causehyperlipidemia and influence hematological indicators
organ rejection - Rapamune | Patient Sirolimus to prevent organ rejection Rapamune Authored by Michael Stewartto preventorgan rejection - Rapamune | Patient Sirolimus to prevent organ rejection Rapamune Authored by Michael Stewart
progression from the G1 phase ( cell growth ) to the S phase ( DNA replication ... resulting in inhibition of the growth of vascular smooth muscle cells , which is a major process of in - stent restenosispreventsprogression from the G1 phase ( cell growth ) to the S phase ( DNA replication ... resulting in inhibition of the growth of vascular smooth muscle cells , which is a major process of in - stent restenosis
graft failure in patients with renal transplantation for antiphospholipid syndromemay preventgraft failure in patients with renal transplantation for antiphospholipid syndrome
in stable multilineage mixed chimerism and long - term graft survivalcan resultin stable multilineage mixed chimerism and long - term graft survival
hyperlipidemia and has also been associated with hepatic artery thrombosis in liver transplant recipientsmay causehyperlipidemia and has also been associated with hepatic artery thrombosis in liver transplant recipients
an elevation of serum lipidscan causean elevation of serum lipids
the translation of proteins that promote cell survival and proliferation by engaging with FK506-binding protein ( FKBPpreventsthe translation of proteins that promote cell survival and proliferation by engaging with FK506-binding protein ( FKBP
cells from progressing from G1 to the S phasepreventscells from progressing from G1 to the S phase
less nephrotoxicity , neurotoxicity , and hypertensioncausesless nephrotoxicity , neurotoxicity , and hypertension
for increased lipophilicitydesignedfor increased lipophilicity
an increase in serum cholesterol and triglyceridesmay causean increase in serum cholesterol and triglycerides
anaemiacan also causeanaemia
the levels of electrolytes such as potassium , sodium , magnesium , chloride , and calcium in the blood to change while taking this medicationmay causethe levels of electrolytes such as potassium , sodium , magnesium , chloride , and calcium in the blood to change while taking this medication
a round higher chance of developing a blood clot , especially fearful when roughly used with cinnarizinecausesa round higher chance of developing a blood clot , especially fearful when roughly used with cinnarizine