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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

6 amino acid differences ( 98.2 % nucleotide sequence similarityresultingfrom single nucleotide polymorphism ( SNP ) differences

restriction - site associated DNA ( RAD ) sequencing on roach samples collected throughout Californiato discoverand genotype thousands of single nucleotide polymorphism ( SNPs

restriction - site associated DNA ( RAD ... collected throughout Californiato discovergenotype thousands of single nucleotide polymorphism ( SNPs

GWAS and understanding how these loci control disease(passive) discovered bysingle nucleotide polymorphism ( SNP ) associations

by GWAS(passive) discovered bysingle nucleotide polymorphism ( SNP ) associations

NFKB1 - 94 insertion / deletioncontributesATTG polymorphism

The Sequenom MassARRAY Assay Design 3.0 software ( San Diego , CA , USA ) was usedto designmultiplexed single nucleotide polymorphism ( SNP

the MNNG(passive) caused bysingle nucleotide polymorphisms ( SNPs

assay(passive) was designedA Taqman single nucleotide polymorphism genotyping

Research leader Jeffrey L. Vallet and his colleaguesdiscovereda single nucleotide polymorphism , or SNP

methodsto discovergenotype single - nucleotide polymorphism

The studyresultsfrom a single - nucleotide polymorphism

on chromosome 19(passive) has been discoveredThis single nucleotide polymorphism

any drugcausingCYP2C19 POLYMORPHISM

Assembly Errors(passive) Caused bySingle Nucleotide Polymorphisms

total 107 scorable bandsresulting87.85 % polymorphism

in the small subunit of the starch biosynthesis rate - controlling enzyme ADP - glucose pyrophosphorylase , which resulted in the introduction of a STOP codon in the messenger RNA of the enzyme(passive) was discoveredA single nucleotide polymorphism ( SNP

in amino acid substitutionresultingin amino acid substitution

to a functional change in the protein being studiedleadsto a functional change in the protein being studied

drug responseinfluencingdrug response

an individual 's diseasecausingan individual 's disease

to the altered gene expression [ 22 , 23could contributeto the altered gene expression [ 22 , 23

IVIg responsiveness of japanese patients with CIDPinfluencesIVIg responsiveness of japanese patients with CIDP

IVIg responsiveness of Japanese patientsinfluencesIVIg responsiveness of Japanese patients

to arterial stiffnesscontributesto arterial stiffness

SNPsinfluencingSNPs

a valine to methionine exchange at position 129causesa valine to methionine exchange at position 129

Amino acid substitutions(passive) caused byAmino acid substitutions

to an amino acid substitution from serineleadingto an amino acid substitution from serine

to an amino acid substitution from serine to asparagineleadingto an amino acid substitution from serine to asparagine

an amino acid substitutioncausesan amino acid substitution

to an amino acid substitutionleadingto an amino acid substitution

an amino acid changecausingan amino acid change

amino acid substitution within the of ankyrincausesamino acid substitution within the of ankyrin

in substitution of a highly conserved amino acidresultedin substitution of a highly conserved amino acid

in a single amino acid exchangeresultingin a single amino acid exchange

in a synonymous amino acid changeresultingin a synonymous amino acid change

an amino acid switch from glutamine to valineresultsan amino acid switch from glutamine to valine

to either a Histidine or an Arginine residue in the enzymeleadsto either a Histidine or an Arginine residue in the enzyme

an amino acid alteration at position Asn34 of the receptorcausingan amino acid alteration at position Asn34 of the receptor

to a glutamine ( Gln ) by arginine ( Arg ) substitution at codonleadingto a glutamine ( Gln ) by arginine ( Arg ) substitution at codon

in protein C resistanceresultsin protein C resistance

in an amino acid switch from glutamineresultsin an amino acid switch from glutamine

the substitution of arginine ( Argcausingthe substitution of arginine ( Arg

SNP ) in the genemay resultSNP ) in the gene

an amino acid alteration at position Asn34 of the receptor ( 89causingan amino acid alteration at position Asn34 of the receptor ( 89

an amino acid substitution within the 11th of 12 ankyrin repeats of ANKK1 ... genecausesan amino acid substitution within the 11th of 12 ankyrin repeats of ANKK1 ... gene

a valine to methionine exchangecausesa valine to methionine exchange

a valine to methionine exchange at position 129causesa valine to methionine exchange at position 129

to a histidine instead of a tyrosine at amino acidleadsto a histidine instead of a tyrosine at amino acid

in a cysteine substitution for arginineresultingin a cysteine substitution for arginine

in a premature stop codon in the coding regionresultsin a premature stop codon in the coding region

to a valineleadsto a valine

changes in amino acidscan causechanges in amino acids

from this studydiscoveredfrom this study

an amino acid change in a near actin - interacting domain of Argcausingan amino acid change in a near actin - interacting domain of Arg

in an amino acid switch from glutamine to valine and that yields an entirely sickled red blood cell with limited capacity to carry oxygenresultsin an amino acid switch from glutamine to valine and that yields an entirely sickled red blood cell with limited capacity to carry oxygen

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Smart Reasoning:

C&E

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