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Qaagi - Book of Why

Causes

Effects

by sepsis(passive) caused bybody homeostasis

Zaredcontributedhomeostasis detruncated bodges

by changes in the number or function of Treg cells , which is related to cigarette smoke exposure(passive) caused byimmune homeostasis

by impairment of immune system , barrier defense , and microbiome , likely related to genetic causes(passive) caused bygut homeostasis

low levels of bacteriamight influencegut homeostasis

Regulatory T lymphocytescan influenceimmune homeostasis

Dr. Auwerx ... energy sensors / effectorsinfluencemetabolic homeostasis

their abilityto influenceimmune homeostasis

a factorinfluencingimmune homeostasis

many tumor - associated factorsinfluencetelomere homeostasis

the potency of each of these speciesto influenceimmune homeostasis

by oxidative stress and mitochondrial dysfunction(passive) caused byintracellular homeostasis

the interplay between external and internal cues(passive) is ... influenced bymetabolic homeostasis

a key factorinfluencingimmune homeostasis

Defects in lymphocytecontributetelomere homeostasis

by a pathogen - encoded GW repeat protein(passive) caused byDicer homeostasis

by a pathogen - encoded GW repeat protein (passive) caused byDicer homeostasis

roles in immune - regulation , metabolism and other physiological processesinfluencephysiological homeostasis

to understandinfluencephysiological homeostasis

UUA(passive) is influenced bySUA homeostasis

Several hormonesinfluenceskeletal homeostasis

studies aimed at identifying how the miRNA pathways respond to attacks by pathogensmay ... leadmiRNA homeostasis

the potentialto ... influenceskeletal homeostasis

such mechanical stimulationcan ... influenceskeletal homeostasis

the immune system(passive) is dynamically influenced by Skeletal homeostasis

by the immune system(passive) is ... influenced byskeletal homeostasis

the immune system(passive) is dynamically influenced bySkeletal homeostasis

by immune cells(passive) is influenced byskeletal homeostasis

by the activity of mitochondria(passive) are influenced byEpidermal homeostasis

Estrogen has been suggestedto influenceskeletal homeostasis

various factorsinfluencingskeletal homeostasis

depression(passive) are influenced byskeletal homeostasis

Probioticsinfluencemucosal homeostasis

reactive lipidsmay influencepodocyte homeostasis

macrophage colony - stimulating factor-1 csf1influencesmacrophage homeostasis

factorsmay influencehaemodynamic homeostasis

by infection , injury or altered neuronal activity(passive) caused byhomeostasis

by various internal or external stressors which leads to accumulation of misfolded or unfolded proteins in the ER lumen(passive) caused byhomeostasis

various internal or external stressors which leads to accumulation of misfolded or unfolded proteins in the ER lumen(passive) caused byhomeostasis

inflammation , oxidative stress , mitochondrial dysfunction and proapoptotic / antiapoptotic dysregulation(passive) caused byPerturbed homeostasis

to human aging and the formation of tumorscontributesto human aging and the formation of tumors

ER stressthereby causingER stress

to the accumulation of unfolded proteins in the lumenleadingto the accumulation of unfolded proteins in the lumen

to cellular apoptosisleadsto cellular apoptosis

to autoimmunityleadingto autoimmunity

to an unpleasant state ( driveleadsto an unpleasant state ( drive

in cellresultin cell

in chronic inflammationresultingin chronic inflammation

to cell deathleadingto cell death

to activation of all three branches of UPR pathwayleadingto activation of all three branches of UPR pathway

to ER stress responseleadingto ER stress response

to the misfolding of proteinsleadto the misfolding of proteins

to an OA phenotypemay leadto an OA phenotype

for plaque formation and atherosclerosiscontributesfor plaque formation and atherosclerosis

to feeding and metabolic disorders leading to such diseases as obesitycan leadto feeding and metabolic disorders leading to such diseases as obesity

to abnormal fetal developmentleadingto abnormal fetal development

to diseases and loss of life alsoleadingto diseases and loss of life also

in some cytotoxic effectsresultingin some cytotoxic effects

in hyperproliferation and loss of differentiationresultingin hyperproliferation and loss of differentiation

to their established antagonismcontributesto their established antagonism

severe ER stress resulting in accumulation of unfolded proteins in the ER and activation of the UPRcausessevere ER stress resulting in accumulation of unfolded proteins in the ER and activation of the UPR

to hyperplastic clonesleadingto hyperplastic clones

to cellular dysfunction and apoptosiscan leadto cellular dysfunction and apoptosis

to insulin resistance and progression toward various metabolic disorders , including cardiovascular disease , obesity , and type 2 diabetescan ... leadto insulin resistance and progression toward various metabolic disorders , including cardiovascular disease , obesity , and type 2 diabetes

in increased oxidative stressresultingin increased oxidative stress

to insulin resistance and diabetes during chronic treatmentcan ... leadto insulin resistance and diabetes during chronic treatment

in various metabolic complicationsresultingin various metabolic complications

to diseasecan leadto disease

to diseaseleadingto disease

to insulin resistance and diabetes during chroniccan ... leadto insulin resistance and diabetes during chronic

ER - stress and apoptotic cell death [ 19causingER - stress and apoptotic cell death [ 19

to development of contractile failuremay contributeto development of contractile failure

to cell deathleading ultimatelyto cell death

in apoptosismay ... resultin apoptosis

to insulin resistance and diabetescan ... leadto insulin resistance and diabetes

in cardiac dysfunctionresultingin cardiac dysfunction

in the abnormal functionscan resultin the abnormal functions

to insulin resistance and DM during chronic treatmentcan ... leadto insulin resistance and DM during chronic treatment

a reduction in inflammation in inflamed cells , which can cause a headachealso causesa reduction in inflammation in inflamed cells , which can cause a headache

to deathleadingto death

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