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too large needlecan causeshear stress on the cell walls
mix in 1 - 2 uL DNA ; gently mixto preventshear stress on cells &
changes in injection pressurecausesunnecessary shear stress on the cells
Rapid flow of blood through the arteries and arteriolescausesshear stress on the endothelial cells
flow arrayscreatelaminar shear stress across the cells
Using a syringe pump ( KdScientific , Holliston , MA ) , DMEM was passed through the flow chambercreatingshear stress on endothelial cells
Dilationresultingfrom shear stress acting on endothelial cells
in vitro(passive) can be preventedShear stress – induced EndoMT in nonciliated cells
mechanical deformation of the endothelial cellresultsmechanical deformation of the endothelial cell
to inflammation ( green arrowsleadsto inflammation ( green arrows
to capillary wall disruptioncontributesto capillary wall disruption
the secretion of subsets of proteinstriggersthe secretion of subsets of proteins
to inactivation of apt channels and activation of the NADPH oxidoreductaseleadsto inactivation of apt channels and activation of the NADPH oxidoreductase
a tensional force in the cytoplasmic tail of PECAM-1 and activates Src family kinase - mediated signaling in a PECAM-1-dependent manner ( 21causesa tensional force in the cytoplasmic tail of PECAM-1 and activates Src family kinase - mediated signaling in a PECAM-1-dependent manner ( 21
to metabolic stress or even cell destructionleadingto metabolic stress or even cell destruction
to metabolic stress or cell destructionleadingto metabolic stress or cell destruction
to the translocation of the ATPledto the translocation of the ATP
to biochemical signaling and mechanical responses of the cellsleadsto biochemical signaling and mechanical responses of the cells