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Qaagi - Book of Why

Causes

Effects

it is believedto influence2nd messenger

their function ... both neuronal and non neuronal cell surfacetriggersecond messenger

narrator oughtto discoversecond messenger

the first messenger neurotransmitter occupying the receptor outside of the cell(passive) is created byThe second messenger

Damnacanthal , which is a anthraquinone isolated from the noni rootsmay influencesecond messenger

to be cyclic AMP ( cAMP(passive) was later discoveredThe second messenger

CPA(passive) caused bythe second messenger

For example , agonist binding activates adenylyl cyclase ,createsthe second - messenger

the ability of partial agoniststo triggersecond - messenger

a cleavage of a phospholipid in the plasma membrane second messenger created by a cleavage of a phospholipid in the plasma membrane(passive) created bysecond messenger

ArticleFigures & DataTransparent Process AbstractThetriggerssecond messenger NAADP

receptor stimulation(passive) created bythe second messenger

arrival at the cell surface of glucagon or epinephrine to stimulate glycogen breakdown(passive) triggered bythe second messenger

phosphorylate inositol lipidsto createsecond messenger phosphoinositides

NO overproduction and mediate cell injury following oxygen and glucose deprivation in SK - N - MC cellsProceedings / Conference:11th Medical Research Conference , Medical Science GroupChan , PS ; Shen , J ; Fung , PCW ; Cheung , RTF2006164 Multiple Dipole Source Analysis of Event - related Potentials to Emotional Facial ExpressionsProceedings / Conferenceto causeNO overproduction and mediate cell injury following oxygen and glucose deprivation in SK - N - MC cellsProceedings / Conference:11th Medical Research Conference , Medical Science GroupChan , PS ; Shen , J ; Fung , PCW ; Cheung , RTF2006164 Multiple Dipole Source Analysis of Event - related Potentials to Emotional Facial ExpressionsProceedings / Conference

cell response phosphatidylinositol signal generating receptors tyrosine kinase receptor or phosphatidylinositol 4',5'-bisphosphatetriggerscell response phosphatidylinositol signal generating receptors tyrosine kinase receptor or phosphatidylinositol 4',5'-bisphosphate

to vascular smooth muscle relaxation via numerous intermediate stepsleadsto vascular smooth muscle relaxation via numerous intermediate steps

gating of a separate ion channelthen causesgating of a separate ion channel

from LH signaling through Gs and Gqresultingfrom LH signaling through Gs and Gq

after a receptor binds a ligandtriggeredafter a receptor binds a ligand

to cellular responseleadingto cellular response

to activation of STING and induction of IFN production [ 29 , 30leadingto activation of STING and induction of IFN production [ 29 , 30

to clinical acneleadingto clinical acne

saliva production in both the parotid and submandibular glands and enzymatic secretion in the parotid glandscausessaliva production in both the parotid and submandibular glands and enzymatic secretion in the parotid glands

a rapid translocation of D1 receptors to the plasma membrane [ 17causesa rapid translocation of D1 receptors to the plasma membrane [ 17

further reactions within the celltriggersfurther reactions within the cell

sential amino groupresultingsential amino group

a series of chemical changes that produce the required responsecausesa series of chemical changes that produce the required response

to the regulation of coronary vascular tone and vasomotor responsecontributesto the regulation of coronary vascular tone and vasomotor response

the cells responsetriggersthe cells response

the release of calcium ions ( Ca+2 ) from the endoplasmic reticulum of the taste cellcausesthe release of calcium ions ( Ca+2 ) from the endoplasmic reticulum of the taste cell

the activation of a protein kinase which activates phosphorylazethen causesthe activation of a protein kinase which activates phosphorylaze

the release of calcium ions ( Ca.sup.+2 ) from the endoplasmic reticulum of the taste cellcausesthe release of calcium ions ( Ca.sup.+2 ) from the endoplasmic reticulum of the taste cell

to regulation of cell growth and differentiationcontributesto regulation of cell growth and differentiation

as derivative of an adenine dinucleotide ( 52 , 53discoveredas derivative of an adenine dinucleotide ( 52 , 53

the activation ( phosphorylation ) ofcausesthe activation ( phosphorylation ) of

the increase in basal chloride conductancecausesthe increase in basal chloride conductance

to the reactive oxygen species ( ROS ) generation in the signal transduction of disease responseleadingto the reactive oxygen species ( ROS ) generation in the signal transduction of disease response

the enzymes that produce the target cell 's responseinfluencingthe enzymes that produce the target cell 's response

in turnsetsin turn

to the phosphorylation of ion channel proteinscan leadto the phosphorylation of ion channel proteins

vesicles to fuse w/ presynaptic membrane Cl hyperpolarizes cell ( inhibitiory effect ) voltage - gated & ligandcausesvesicles to fuse w/ presynaptic membrane Cl hyperpolarizes cell ( inhibitiory effect ) voltage - gated & ligand

to ERK activationleadsto ERK activation

to datediscoveredto date

to primary afferent hyperalgesiacontributesto primary afferent hyperalgesia

the release of calcium ions ( Ca++ ) from the endoplasmic reticulum of the taste cellcausesthe release of calcium ions ( Ca++ ) from the endoplasmic reticulum of the taste cell

calcium ion to be released from intracellular storescausescalcium ion to be released from intracellular stores

to increased calcium availability at the actin - myosin complexes and thus increased contractilityleadsto increased calcium availability at the actin - myosin complexes and thus increased contractility

release of calcium from endoplasmic reticulum into cytosol Inositol trisphosphate ( IP3 ) enzyme that phosphorylates certain intracellular proteins when activated by diacylglycerol Protein kinase C intracellular calcium - binding protein that mediates many of calcium 's second - messenger functions Calmodulin an intracellular enzyme that , when activated by calcium and the protein calmodulin , phosphorylates many protein substrates within cellscausesrelease of calcium from endoplasmic reticulum into cytosol Inositol trisphosphate ( IP3 ) enzyme that phosphorylates certain intracellular proteins when activated by diacylglycerol Protein kinase C intracellular calcium - binding protein that mediates many of calcium 's second - messenger functions Calmodulin an intracellular enzyme that , when activated by calcium and the protein calmodulin , phosphorylates many protein substrates within cells

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