To date four different enzyme deficiencies have been foundto causeSanfilippo
both DiChiacchio and Dobbyn ... the mutated genecausesSanfilippo
That charity workledSanfilippo
the deficiency of one of the enzymes required to degrade a complex sugar called heparan sulfate(passive) is caused bySanfilippo
a lack of the SGSH enzyme , which helps to break down and recycle long chain sugars(passive) is caused bySanfilippo
Family , work and financial obligationspreventedSanfilippo
an enzyme deficiency that prevents cells ’ natural recycling process , leading to waste accumulation , cellular malfunction and eventually , cell death(passive) is caused bySanfilippo
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the mutationcausingSanfilippo
changes to genes that prevents the body from producing enzymes that are needed to recycle waste within the cells of the body(passive) is caused bySanfilippo
the build - up of sugar chains called glycosaminoglycans or ‘ GAGs ’ within the cells(passive) is caused bySanfilippo
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the night ’s boozy concoctions with fellow cofounder Cappy Sorentinocreatedthe night ’s boozy concoctions with fellow cofounder Cappy Sorentino
the cell damage(passive) caused bythe cell damage
the secondary damage(passive) caused bythe secondary damage
severe neurological damagecausessevere neurological damage
the symposium ... Bud Peterson , president of Georgia Institute of Technology ; and Kenneth Brigham , associate vice president for predictive healthwill leadthe symposium ... Bud Peterson , president of Georgia Institute of Technology ; and Kenneth Brigham , associate vice president for predictive health
the 166-member department , including more than 140 sworn officershas ledthe 166-member department , including more than 140 sworn officers
an excellent mood piece for those who do want to get lost in an audio mystery as new layers of piano are unveiled – and if you have your imagination with you – you can wander off anywherehas createdan excellent mood piece for those who do want to get lost in an audio mystery as new layers of piano are unveiled – and if you have your imagination with you – you can wander off anywhere
Platinum ’s valuation committee , which is responsible for valuing Platinum ’s assetsleadsPlatinum ’s valuation committee , which is responsible for valuing Platinum ’s assets
a guide that fits all in its flexibilityhas ... createda guide that fits all in its flexibility
the Muleriders with three rushing touchdowns , including last Saturday 's career - best 65-yard touchdown jauntleadsthe Muleriders with three rushing touchdowns , including last Saturday 's career - best 65-yard touchdown jaunt
Tampa BayledTampa Bay
the Raiders to an era of prosperity which has included the first run of three - straight 20-win seasons in program history and berths in each of the last three NACC Tournamentshas ledthe Raiders to an era of prosperity which has included the first run of three - straight 20-win seasons in program history and berths in each of the last three NACC Tournaments
mournful melodies that are delightfully dark and hauntingcreatesmournful melodies that are delightfully dark and haunting
every significant passing recordsetevery significant passing record
the growth of the company over an eight - year period with an improvement in operating margins of over 1,200 basis points from the mid - teens to more than 28 %ledthe growth of the company over an eight - year period with an improvement in operating margins of over 1,200 basis points from the mid - teens to more than 28 %
Pinnacle ’sledPinnacle ’s
a recent walking tour(passive) led bya recent walking tour
every member of the family to make sacrifices andcausesevery member of the family to make sacrifices and
the team to 13 victoriesledthe team to 13 victories
major behavioral issueshas causedmajor behavioral issues
furniturehas createdfurniture
a complex mixture of emotive songs ... reaching through the melancholic chords of ‘ A Door Opens Forever ’ to the stirring , sometimes haunting tones of the title track , while managing to capture every inch of the emotive spectrum inbetweenhas createda complex mixture of emotive songs ... reaching through the melancholic chords of ‘ A Door Opens Forever ’ to the stirring , sometimes haunting tones of the title track , while managing to capture every inch of the emotive spectrum inbetween
the company through significant growthhas ledthe company through significant growth
seizurescan causeseizures
an elegant solution to improve performance in tough big data use casescreatedan elegant solution to improve performance in tough big data use cases
a fully automated production system , including a computer - controlled roasting system capable of processing up to 4,000 pounds per hourdesigneda fully automated production system , including a computer - controlled roasting system capable of processing up to 4,000 pounds per hour
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a school recordseta school record
a lineup of new , sugar - free recipes perfect for those on the program or simply looking for a healthier alternative to the typical recipeis creatinga lineup of new , sugar - free recipes perfect for those on the program or simply looking for a healthier alternative to the typical recipe
children to regress and eventually slip into dementia , and similar diseasescauseschildren to regress and eventually slip into dementia , and similar diseases
the company in becoming listed on the Nasdaq with then annual revenues of $ 151 millionledthe company in becoming listed on the Nasdaq with then annual revenues of $ 151 million
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her sinus cavities(passive) caused byher sinus cavities
both countiesledboth counties
the squadledthe squad
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Carson to be delayed in most aspects of his lifehas causedCarson to be delayed in most aspects of his life
a third record for most yards rushed in a single gamealso seta third record for most yards rushed in a single game