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Qaagi - Book of Why

Causes

Effects

TTR Amyloidosis - associated cardiomyopathy ( ATTR - CM ) , caused by TTR amyloid infiltration of the myocardium and conduction systemresultsin a restrictive cardiomyopathy associated with atrial arrhythmias , progressive heart failure with preserved ejection fraction in early phases

a factorcontributingto heart failure with preserved ejection fraction in patients with atrial fibrillation

Impaired myocardial relaxationresultingin diastolic dysfunction [ i.e. , Heart failure with preserved ejection fraction ( HFpEF

any clinical benefitresultingfrom stem cell therapy for heart failure with reduced ejection fraction

first(passive) was ... discoveredDiastolic Heart Failure Overview Historical Perspective Heart failure with preserved ejection fraction

Impaired myocardial oxygen availabilitycontributesto abnormal exercise hemodynamics in heart failure with preserved ejection fraction

important mechanismscontributingto the development of heart failure with preserved ejection fraction

more pronounced diastolic dysfunctionmay contributeto their greater predisposition for heart failure with preserved ejection fraction

Systolic HF ... weakened ventricular contractionsresultin heart failure with reduced ejection fraction ( HFrEF

Impaired cardiac relaxationalso contributesto a form of heart failure termed heart failure with preserved ejection fraction

NO ) availabilitymay contributeto the pathophysiology of heart failure with preserved ejection fraction ( HFpEF

the world 's first transcatheter devicedesignedto treat heart failure with preserved ejection fraction

myocardial systolic dysfunction with LV diastolic dysfunctioncould leadto heart failure with preserved ejection fraction ( HFpEF

ventricular diastolic dysfunctionleadingto heart failure with preserved ejection fraction ( HFpEF

diastolic dysfunctionleadingto heart failure with preserved ejection fraction ( HFpEF

left ventricular ( LV ) diastolic dysfunctionleadingto heart failure with preserved ejection fraction ( HFpEF

diastolic dysfunction , which is a heart relaxation abnormalitycontributesto heart failure with preserved ejection fraction ( HFpEF

oxidative stress and vascular dysfunctioncontributeto heart failure with preserved ejection fraction ( HFPEF

a heart relaxation abnormalitycontributesto heart failure with preserved ejection fraction ( HFpEF

The mechanismcausingheart failure with preserved ejection fraction ( HFPEF

NO ) availabilitymay contributeto the pathophysiology of heart failure with preserved ejection fraction

oxidative stress and vascularcontributeto heart failure with preserved ejection fraction ( HFPEF

Mechanismsleadingto symptomatic heart failure with preserved ejection fraction

Microvascular functions such as control of blood flow and inflammationcontributeto heart failure with preserved ejection fraction ( HFpEF

Cardiac fibrosis ... diastolic dysfunctioncan ... resultin heart failure with preserved ejection fraction

a diastolic dysfunctionresultingin heart failure with preserved ejection fraction

diastolic dysfunctioncan ... leadto heart failure with preserved ejection fraction

by diastolic dysfunction(passive) caused bypreserved ejection fraction Heart failure

enlargement of the left ventricle wall(passive) is caused byHeart failure with preserved ejection fraction

Stiffening of the left ventriclecontributesheart failure with preserved ejection fraction

Other devicesmay causeheart failure with preserved ejection fraction

especially thoseleadingto heart failure with preserved ejection fraction

your childmay resultin preserved ejection fraction heart disease

The addition of VEGF into the transfection cocktailresultedin a 4-fold improvement in the cardiac ejection fraction

RSK3-mAKAP signaling , a signal transduction network that is involved in cardiac remodeling ... cardiovascular diseaseresultsin heart failure with preserved ejection fraction

study(passive) was designedstudy

to an increased risk for all - cause and cardiovascular mortalityleadsto an increased risk for all - cause and cardiovascular mortality

Systolic HF(passive) is caused bySystolic HF

in exertion - limiting shortness of breath and fatigueresultingin exertion - limiting shortness of breath and fatigue

in an elevated RAPwould resultin an elevated RAP

The drug(passive) is designedThe drug

patients ' outcomesinfluencedpatients ' outcomes

in cardiac failureresultsin cardiac failure

to increasedleadingto increased

to HFpEFcontributeto HFpEF

An acute reticular pattern(passive) is most frequently caused byAn acute reticular pattern

to exercise intolerance in obesitymay contributeto exercise intolerance in obesity

to filling abnormalitiescontributesto filling abnormalities

the heart to pump out less blood than normalcausesthe heart to pump out less blood than normal

to decreased stroke volumeleadsto decreased stroke volume

lung remodeling characterized by myofibroblasts proliferation and fibrosis leading to a restrictive lung syndrome contributing to PH and RV dysfunctioncauseslung remodeling characterized by myofibroblasts proliferation and fibrosis leading to a restrictive lung syndrome contributing to PH and RV dysfunction

lung remodelling with myofibroblasts proliferation and fibrosis leading to a restrictive lung syndrome with pulmonary hypertension ( PH ) and right ventricular ( RV ) dysfunctioncauseslung remodelling with myofibroblasts proliferation and fibrosis leading to a restrictive lung syndrome with pulmonary hypertension ( PH ) and right ventricular ( RV ) dysfunction

The company 's interatrial shunt device ( IASD ) , a trans - catheter device and non - surgical medical device(passive) is designedThe company 's interatrial shunt device ( IASD ) , a trans - catheter device and non - surgical medical device

to heart failure hospitalizationscontribute equallyto heart failure hospitalizations

the balance(passive) caused bythe balance

HFpEFresultsHFpEF

after a widow maker , triple blockagediscoveredafter a widow maker , triple blockage

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