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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

An illness or injury that results in prolonged bed restmay causedisuse atrophy of the quadriceps muscles

the molecular mechanismscausingPABPN1-mediated muscle wasting

prolonged usecan causeimmunosuppression , muscle wasting

Dexamethasonecan causemuscle wasting , decreasing muscle

Fludrocortisonecan causemuscle wasting , decreasing muscle

Corticosteroids such as budesonidecan causemuscle wasting , decreasing muscle

diseasescausewasting of lean muscles

diseasesdo causewasting of lean muscles

by starvation and inactivity(passive) caused byacute muscle wasting

diseasescausesmuscle wasting and muscle atrophy

Watching TV slows down the brains potentialcausesatrophy ( muscle wasting ) of core muscles

Cervical collars and immobilizationmay causemuscle atrophy ( muscle wasting

conditionscausingmuscle wasting / atrophy

muscle weaknessleadingto muscle wasting ( muscle atrophy

Progressive muscular atrophy ( PMA ... slowly but progressivelycausesmuscle wasting ( atrophy

that slowly butprogressively causesmuscle wasting atrophy

slowly butcausesmuscle wasting atrophy

that slowly butcausesmuscle wasting atrophy

slowly but progressivelycausesmuscle wasting atrophy

by AZT(passive) caused bythe myopathy ( muscle wasting

by the inability(passive) caused byatrophy - muscle wasting

hip dysplasia or cruciate ruptures , which tendto causewasting of the extensor muscles

Denervated muscle fibres atrophy in timecausingwasting of muscle

negative nitrogen balanceresultingwasting of muscles

that muscular dystrophycauseswasting of the muscle

Neurogenic thoracic outlet syndromecan causewasting of the muscle

Spinal stenosisalso may causemuscle atrophy ( wasting

Quadriceps weakness andmay contributequadriceps muscle imbalance

so longwill causemuscle - Wasting catabolism

failure to do socan causeirreparable muscle wasting

by various diseases(passive) caused byalleviate muscle wasting

Low proteincausesmuscle wasting

diet - induced protein loss , could causemuscle wasting

by mutations in the DMD gene(passive) is causedmuscle wasting

by the inadequate intake of protein(passive) caused bymuscle wasting

Spinal muscular atrophy ... a rare and progressive genetic disordercausesmuscle wasting

protein losscould causemuscle wasting

muscle catabolic factorscausemuscle wasting

Bed rest and inactivitycan causemuscle wasting

Even moderate protein insufficiencymay causemuscle wasting

ankle , knee and low back paincausingankle , knee and low back pain

repeated stress and strain on the bony prominence where the patella tendon attaches onto the shin bonecan causerepeated stress and strain on the bony prominence where the patella tendon attaches onto the shin bone

repeated straincan causerepeated strain

repeated strain ( repeated extensioncan causerepeated strain ( repeated extension

repeated stresscan causerepeated stress

repeated strain on the attachment of the patellar ligament to the growing tibiacan causerepeated strain on the attachment of the patellar ligament to the growing tibia

repeated stress and straincan causerepeated stress and strain

alsomay resultalso

repeated stress and strain on the attachment of the patella ligament to the growing tibiacan causerepeated stress and strain on the attachment of the patella ligament to the growing tibia

to premature agingleadsto premature aging

to severe disabilityleadsto severe disability

to the extension of the leg and flexion of the thighcontributesto the extension of the leg and flexion of the thigh

in a muscle tearcan resultin a muscle tear

a vicious cycle in placesetsa vicious cycle in place

in decreased muscle functionresultedin decreased muscle function

in loss of independenceresultsin loss of independence

him backsethim back

knee paincauseknee pain

to upper leg thigh and kneecan contributeto upper leg thigh and knee

to deathcan leadto death

weakness of the arm / leg , etccausesweakness of the arm / leg , etc

involuntary extension in the decrease legcausinginvoluntary extension in the decrease leg

in involuntary extension of the reduced legresultingin involuntary extension of the reduced leg

in involuntary extension on the decreased legresultingin involuntary extension on the decreased leg

to knee stabilitycontributesto knee stability

to reduced functionleadingto reduced function

involuntary extension on the lower legcausinginvoluntary extension on the lower leg

to the discovery of proteasome inhibitorsledto the discovery of proteasome inhibitors

to atrophyleadingto atrophy

to knee osteoarthritismight leadto knee osteoarthritis

to the discovery of proteasome inhibitors , a novel class of drugs that is effective against the blood cancer , multiple myelomaledto the discovery of proteasome inhibitors , a novel class of drugs that is effective against the blood cancer , multiple myeloma

in some individualsresultedin some individuals

to excessive degradation of important smooth muscle cell proteinsmight leadto excessive degradation of important smooth muscle cell proteins

knee pain can develop , and performance will surely be lostmay resultknee pain can develop , and performance will surely be lost

severe weight loss(passive) is ... caused bysevere weight loss

to a lack of joint control as well as problems with gait and balanceleadsto a lack of joint control as well as problems with gait and balance

to weakness and severe fatigueleadingto weakness and severe fatigue

in the legresultingin the leg

to this weight lossdoes contributeto this weight loss

to the weight losscould be contributingto the weight loss

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Smart Reasoning:

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