by chemical and/or thermal(passive) caused byprotein denaturation
a o heatingcausesprotein denaturation
the heatingcausesprotein denaturation
some functional group of proteins ... metal ionwould causeprotein denaturation
a treatmentcausesprotein denaturation
Stress to the cellcausesprotein denaturation
High temperaturecausesprotein denaturation
cherubismcausescherubism
in a defective proteinresultsin a defective protein
of various amino acidscomposedof various amino acids
of little units identified as amino acidscomposedof little units identified as amino acids
of carbon , hydrogen , oxygen , and nitrogenare composedof carbon , hydrogen , oxygen , and nitrogen
to treatment for inflammatory diseases 7could leadto treatment for inflammatory diseases 7
protein phosphorylationcausesprotein phosphorylation
in increased phosphorylation of various substratesresultin increased phosphorylation of various substrates
in growth arrest and death of cancer cellsresultingin growth arrest and death of cancer cells
in the activation of nuclear transcription factors leading to cell differentiation and growthresultin the activation of nuclear transcription factors leading to cell differentiation and growth
to activation of MAPKultimately leadingto activation of MAPK
of both cytosolic and receptor protein kinasescomposedof both cytosolic and receptor protein kinases
in a cellular responseresultsin a cellular response
to activation ofleadsto activation of
to their activationleadingto their activation
as being involved in the regulation of the cell cycleoriginally discoveredas being involved in the regulation of the cell cycle
to the degradation of proteins and membranesleadingto the degradation of proteins and membranes
in vitro cell responsescontributein vitro cell responses
cellular effectscausecellular effects
to the activation and translocation of an enzyme termedleadingto the activation and translocation of an enzyme termed
to uncontrolled cell proliferation , such as in cancercan leadto uncontrolled cell proliferation , such as in cancer
to MAP activationleadto MAP activation
to apoptosisleadto apoptosis
as being involved in the regulation of the _originally discoveredas being involved in the regulation of the _
to in vivoleadingto in vivo
in vivoleadingin vivo
in the stimulation of the cell cycleresultsin the stimulation of the cell cycle
for their role in regulating the cell cyclefirst discoveredfor their role in regulating the cell cycle
in induction of gene expressionresultin induction of gene expression
to changes in cytoskeletal dynamics and cell contractilityleadto changes in cytoskeletal dynamics and cell contractility
to in vitro cell responses to culture substratescontributeto in vitro cell responses to culture substrates
to changes in their activitiesleadsto changes in their activities
to the initiation of gene expressionleadsto the initiation of gene expression
protein to lose shape loss of shapecausesprotein to lose shape loss of shape
significantly in the regulationcontributesignificantly in the regulation