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Qaagi - Book of Why

Causes

Effects

to block the substances ( proteins ) that lead to that growth , which include vascular endothelial growth factor ( VEGF ) and placental growth factor(passive) are designedAngiogenesis inhibitors

Dr. Folkman and his colleaguesdiscoveredangiogenesis inhibitors

from a variety of sources(passive) have been discoveredAngiogenesis inhibitors

to prevent the formation of new blood vessels(passive) are designedAngiogenesis inhibitors

to stop tumours growing by cutting off their blood supply(passive) are designedAngiogenesis inhibitors

based on the structural data for AIDS therapy(passive) were successfully designedProtease inhibitors

to limit the effects of a cell structure called a proteasome(passive) are designedProteasome inhibitors

also(passive) are ... influencedTrypsin inhibitors

to mimic the transition state of the protease 's actual substrates(passive) were designedProtease inhibitors

the drug(passive) were discoveredProtease inhibitors

to target(passive) were designedprotease inhibitors

from natural sources , including : tree bark , fungi , shark muscle and cartilage , sea coral , green tea and herbs(passive) have been discoveredAngiogenesis inhibitors

The workleadingto protease inhibitors

Our groupis discoveringprotease inhibitors

biopharmaceutical researchersdiscoveredprotease inhibitors

first(passive) were ... inventedprotease inhibitors

functionalized peptide moleculesdesignedas protease inhibitors

to do not meanresultsfrom protease inhibitors

to block certain enzymes the virus needs to replicate(passive) are designedProtease inhibitors

Coadministration of desloratadine withresultsCYP3A4 inhibitors

Baker ... blood and cholesterol imbalancesresultfrom protease inhibitors

Deaths from HIV / AIDS , which was relatively unknown in 1980 ... biopharmaceutical researchersdiscoveredprotease inhibitors

drugsmay ... causereuptake inhibitors

to regulate glucose by manipulating a protein found in the renal system(passive) are designedSGLT2 inhibitors

The combination of Adderall and selective serotoninresultsreuptake inhibitors

to inhibit renal glucose reabsorption with the goal of lowering blood glucose(passive) are designedSGLT2 inhibitors

to control diabetes by blocking reabsorption(passive) are designedSGLT2 inhibitors

e. Early attempts , dating deny to the late sto discoverCOMT inhibitors

a targeted programto discoverPARG inhibitors

to keep the protein from performing its function(passive) are designedSGLT2 inhibitors

to control diabetes by blocking reabsorption of glucose by the kidneys , impacting normal kidney function and allowing more sugar to be passed from the body through urine(passive) are designedSGLT2 inhibitors

from natural sources , including tree bark , fungi , shark muscle and cartilage , sea coral , green tea and herbs ( licorice , ginseng , cumin , garlic(passive) have been discovered Angiogenesis inhibitors

from natural sources , including tree bark , fungi , shark muscle and cartilage , sea coral , green tea , and herbs ( licorice , ginseng , cumin , garlic(passive) have been discoveredAngiogenesis inhibitors

with the aim of developing analgesic and antihypertensive agents that act by preventing neprilysin 's activity against signaling peptides such as enkephalins , substance P , endothelin , and atrial natriuretic peptide(passive) have been designedInhibitors Inhibitors

to disrupt the function of the Wee1 protein kinase ( which helps to regulate the cell cycle ) and to cause tumor cells to divide without undergoing the normal DNA repair process , ultimately leading to tumor cell death(passive) are designedWee1 inhibitors

hypotensionto causehypotension

apoptosiscausedapoptosis

to hyperphosphorylation of AKTcan leadto hyperphosphorylation of AKT

gluten - induced intestinal symptoms in wild - type mice and increase inflammation to gluten in genetically susceptible miceinfluencegluten - induced intestinal symptoms in wild - type mice and increase inflammation to gluten in genetically susceptible mice

severe hypertension and even deathcan causesevere hypertension and even death

intestinal inflammationcauseintestinal inflammation

the protease loss(passive) caused bythe protease loss

pancreatic enlargementcan causepancreatic enlargement

to pancreatic diseasecan leadto pancreatic disease

to low blood pressurecould leadto low blood pressure

in the production of immature , non - infectious viral particlesresultin the production of immature , non - infectious viral particles

to stunted growth and pancreatic disordersledto stunted growth and pancreatic disorders

greater bone loss than other classes of HIV drugsmay causegreater bone loss than other classes of HIV drugs

an increase in atorvastatin levelscausean increase in atorvastatin levels

to inhibit the HIV proteasewere ... designedto inhibit the HIV protease

to block HIV viral replicationdesignedto block HIV viral replication

greater bone loss compared to other drugscausegreater bone loss compared to other drugs

to stunted growthcausedto stunted growth

to stunted growth andledto stunted growth and

stunted growthcausedstunted growth

stunted growth and pancreatic problems in test animalshave causedstunted growth and pancreatic problems in test animals

to block HIV viraldesignedto block HIV viral

in wheatdiscoveredin wheat

potent suppression of HIV replicationcausepotent suppression of HIV replication

the digestion of proteininfluencethe digestion of protein

increased pimozide plasma concentrationscan leadincreased pimozide plasma concentrations

a poor protein digestioncausea poor protein digestion

metabolic disturbances , including an increase in both cholesterol and triglyceridescan causemetabolic disturbances , including an increase in both cholesterol and triglycerides

as " HIV - specifichave ... been designedas " HIV - specific

to the prevention of oral infectionscontributeto the prevention of oral infections

to be active against HIVspecifically designedto be active against HIV

variety of side effectscausevariety of side effects

to the production of non - infectious ( non - functional ) viral particlesleadto the production of non - infectious ( non - functional ) viral particles

digestive problemscausingdigestive problems

to the prevention of the digestion of proteinleadto the prevention of the digestion of protein

increased bleeding in hemophiliacscan causeincreased bleeding in hemophiliacs

a treatmentcan causea treatment

to prevent the HIVdesignedto prevent the HIV

in release of immature , noninfectious viral particlesresultingin release of immature , noninfectious viral particles

side effectscan causeside effects

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