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Qaagi - Book of Why

Causes

Effects

1989 - 08 - 23 1992 - 11 - 24 Roussel Uclaf Amino acid cyclopentanophenonthrene compounds " Cellular MechanismsInfluencingthe Aqueous Humor Outflow Pathway

prolonged use of latex - free gloves of synthetic rubber , vinyl , nitrile , neoprene , or other structures ,resultingin venous outflow of aqueous humor

Surgical interventions usually involvecreatingnew pathways for drainage of aqueous humor

IOP elevation in the rat eye ... the episcleral veinleadsto sclerosis of the aqueous humor outflow pathway

morphological and biochemical changes in the trabecular meshwork.22 Much of the trabecular meshwork cell function , gene expression and extracellular matrix metabolism(passive) caused byreduced aqueous humor outflow

acute closed angle glaucoma Section of iris is removedto createpathway for flow of aqueous humor GlaucomaSurgical Interventions

Chronic elevation of rat intraocular pressure ( IOP ) leading to optic nerve damage ... hypertonic salinecausedsclerosis and blockade of aqueous humor outflow pathways

a mixture of factors of overproduction of aqueous humor and anatomical problems within eye(passive) be caused bydegenerative changes in aqueous humor outflow tracts

Elevated IOP ... the obstruction of the iris - trabecular meshwork in the iridocorneal angle of the eyecausesblockage of the aqueous humor outflow

to elevated intraocular pressure in POAGleadingto elevated intraocular pressure in POAG

Elevated intraocular pressure in glaucoma patients(passive) is caused byElevated intraocular pressure in glaucoma patients

to exploration and development of a promising new class of drugs for treatment of OHT and POAGhas ledto exploration and development of a promising new class of drugs for treatment of OHT and POAG

increased outflow resistance particularly in the trabecular meshwork ( TMcauseincreased outflow resistance particularly in the trabecular meshwork ( TM

to IOP elevation and subsequent RGC and optic nerve axon degeneration two months post - treatmentleadsto IOP elevation and subsequent RGC and optic nerve axon degeneration two months post - treatment

increased pressure in the eyeball opacity of the clear protein filaments of the lens what s an endocrine glandcausingincreased pressure in the eyeball opacity of the clear protein filaments of the lens what s an endocrine gland

to elevated IOPcould leadto elevated IOP

Elevation of intraocular pressure(passive) is mainly caused byElevation of intraocular pressure

to ocular hypertensionleadingto ocular hypertension

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