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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the lenscausinga blockage to the flow of the aqueous humor towards the canal of schlemm

a small cyclodialysisprovokesrelaxation of muscle fibers and increases aqueous humor drainage trough uveoscleral outflow pathway

pilocarpinecausescontraction of the ciliary muscle ... increasing the outflow of aqueous humor

mostly human PCAG including shallow or closed anterior chamber and the obstruction of the iris - trabecular meshwork contact in the iridocorneal angle of the eyecausesblockage of the aqueous humor outflow and elevated IOP

to reduce IOPresultingfrom impaired aqueous humor drainage in the trabecular meshwork and/or Schlemm canal

intraocular tumorscan causeglaucoma by physically blocking the aqueous humor outflow pathway

the trabecular meshworkleadsto increased denial to aqueous humor outflow

a dysfunctional crosstalkcan resultin dysregulated aqueous humor outflow influencing glaucoma pathogenesis

trabecular meshwork ( TM ) cellsresultingin IOP reduction.1 Conventional aqueous humor outflow

These changesleadto blockage of the flow of aqueous humor

a unique mechanism of actionresultsin increased outflow of aqueous humor through the trabecular meshwork

... in turnleadsto a decrease in aqueous humor secretion

the anterior chamber angle developmentcan resultin the blockage of aqueous humor outflow

This inhibitionleadsto a decrease in aqueous humor secretion

Elevated IOP ... the eyecausesblockage of the aqueous humor outflow

ocular hypertension ... the anterior chamber angle developmentcan resultin the blockage of aqueous humor outflow

Secondary glaucoma ... damage or changes to the structures of the eyecausea blockage in aqueous humour outflow

Causes contraction of iris sphincterleadingto increased aqueous humor outflow

trabecular meshwork damageleadsto obstruction of aqueous humor outflow

Glaucomaresultsfrom obstructed outflow from the aqueous humor of the eye

because of their known functioncould ... influenceaqueous humor outflow facility

MB gradually accumulating in the angle of the anterior chambercausingthe outflow blockage of aqueous humor

neovascular growthleadsto complete blockade of aqueous humor outflow

Increased IOPresultsfrom a decrease in aqueous humor outflow

changes in the expression of genes that are known to be involved in cell protection as well as genes ... because of their known functioncould ... influenceaqueous humor outflow facility

trap the lens in the anterior chamberleadingto an obstruction of outflow of aqueous humour Aqueous humour

trap the lens in the anterior chamberleadingto an obstruction of outflow of aqueous humour

in which the iridocorneal angle progressively closes over timeresultingin obstruction of aqueous humor outflow

ITCcausesobstruction of aqueous humor outflow

Angle - closure glaucoma ... the anterior chamber of the eyeresultsimpaired drainage of aqueous humor

Dysfunction of the trabecular meshwork ( TMresultingin decreased outflow of aqueous humor

the pathophysiological eventsleadingto reduced aqueous humor outflow

the TMleadingto decreased aqueous humor outflow

surgerydesignedto enhance aqueous humor outflow

receptorscause Secretory epithelium of the ciliary body to produce aqueous humour

receptorscauseSecretory epithelium of the ciliary body to produce aqueous humour

Angle closureleadsto impaired aqueous humor outflow

Primary open - angle glaucoma ... which in turn is believedto resultfrom impaired outflow of aqueous humour

Cellular mechanismsinfluencingthe aqueous humor outflow pathway

when exposed to various stressesresultingin dysregulation of aqueous humor outflow

to elevated IOPcontributesto elevated IOP

a rapid increases in intraocular pressurecausesa rapid increases in intraocular pressure

to decreased aqueous humor outflow facilitycontributeto decreased aqueous humor outflow facility

to decreased aqueous humor outflow facility following acute elevation of intraocular pressure ( IOP ) in bovine eyescontributeto decreased aqueous humor outflow facility following acute elevation of intraocular pressure ( IOP ) in bovine eyes

to decreased aqueous humor outflow facility after acute elevation of intraocular pressure ( IOP ) in bovine eyescontributeto decreased aqueous humor outflow facility after acute elevation of intraocular pressure ( IOP ) in bovine eyes

to decreased aqueous humor outflow facility after acute elevation of intraocular pressure ( IOP ) in bovine eyescontributeto decreased aqueous humor outflow facility after acute elevation of intraocular pressure ( IOP ) in bovine eyes

in rapid elevation of eye pressureresultingin rapid elevation of eye pressure

the IOP of the eyecan influencethe IOP of the eye

Increased intraocular pressure ( IOP(passive) is caused byIncreased intraocular pressure ( IOP

intraocular pressure ( IOP(passive) is caused byintraocular pressure ( IOP

IOP(passive) is causedIOP

IOP(passive) is caused byIOP

IOP(passive) is caused byIOP

The elevated intraocular pressure ( IOP ) of primary open - angle glaucoma(passive) is caused byThe elevated intraocular pressure ( IOP ) of primary open - angle glaucoma

a condition(passive) caused bya condition

elevation in IOPcauseselevation in IOP

elevated intraocular pressurecauseselevated intraocular pressure

the eye(passive) caused bythe eye

Elevation of intraocular pressure(passive) is mainly caused byElevation of intraocular pressure

increased pressurecausesincreased pressure

increased pressure in the posterior chambercausesincreased pressure in the posterior chamber

a drop in IOP(passive) caused bya drop in IOP

this pressure to increase to about 50 mm of mercurycausesthis pressure to increase to about 50 mm of mercury

reduced IOP(passive) caused byreduced IOP

symptomsto causesymptoms

to the formation of a filtering blebleadsto the formation of a filtering bleb

Increased intraocular pressure ( IOP(passive) caused byIncreased intraocular pressure ( IOP

pressure to build in eyecausespressure to build in eye

to collapse of the trabecular meshwork ( known as angle recessionleadingto collapse of the trabecular meshwork ( known as angle recession

an increase in IOP , which is the major risk factor for glaucomacan causean increase in IOP , which is the major risk factor for glaucoma

to glaucomaleadingto glaucoma

The elevated intraocular pressure ( IOP ) of primary open - angle glaucoma(passive) is caused byThe elevated intraocular pressure ( IOP ) of primary open - angle glaucoma

Most common characteristic of POAG(passive) is caused byMost common characteristic of POAG

oftenresultsoften

Elevated IOP(passive) is caused byElevated IOP

in reduction in intraocular pressureresultsin reduction in intraocular pressure

elevated IOPcan causeelevated IOP

in bleb formationresultingin bleb formation

Almost all elevated pressures(passive) are caused byAlmost all elevated pressures

Increased intraocular pressure ( IOP(passive) is caused byIncreased intraocular pressure ( IOP

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Smart Reasoning:

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