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to a good clinical response in 36 % of patientsledto a good clinical response in 36 % of patients
in improvement in 19 of 51 patients and stabilization of 13 patientsresultedin improvement in 19 of 51 patients and stabilization of 13 patients
to the development of end - stage renal disease compared with patients on regimens containing cytotoxic drugsleadsto the development of end - stage renal disease compared with patients on regimens containing cytotoxic drugs
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side effectsmay causeside effects
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significant problems for the patient over timeto causesignificant problems for the patient over time
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to preserve dose intensity and minimize toxicitydesignedto preserve dose intensity and minimize toxicity
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