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Qaagi - Book of Why

Causes

Effects

the potential factorscreatedpopulation structure

environmental factorsinfluencepopulation structure

landscape factorsinfluencingpopulation structure

disentangle factorsinfluencingpopulation structure

different factorshave influencedpopulation structure

socio - cultural factorsinfluencingpopulation structure

three main factorsinfluencingpopulation structure

Natural history and factorsinfluencingpopulation structure

This variation ... site - specific ecological factorsinfluencepopulation structure

Key missing factors ... geography (influencespopulation structure

Professor Phillips - Conroy 's studies of free - ranging primates ... how behavioral , demographic , and ecological variables functionto influencepopulation structure

extrinsic factors , such as landscape architecture and dispersal barriers(passive) is influenced byPopulation structure

both multiple factors and multiple interactions between factors were foundto influencepopulation structure

The analysis of genetic variation in natural years populations ... the particular biological factorsinfluencepopulation structure

At a regional scale , isolation - by - distance has been shownto influencepopulation structure

the severe population bottleneck that most likely occurs during the maternal transmission of Wolbachia to microfilariae and the accumulation of new mutations during the subsequent population expansion from the larval to adult stage and the long adult life span ( up to 14 years(passive) is influenced byWolbachia population structure

genetic differentiation(passive) caused bypopulation structure

Changes to social , environmental and economic conditionscan also influencepopulation structure

a high proportion of elderly households(passive) caused bypopulation structure

collection by people and by the type of substrate(passive) can be influenced bypopulation structure

significant percentage of young professional individuals(passive) caused bypopulation structure

local dispersalcreatepopulation structure

Dispersal ability ... an important ecological factorcan influencepopulation structure

changes in age range and population growth(passive) caused bypopulation structure

distributional changes in the past(passive) to have been influenced bypopulation structure

The ability for organisms to disperse throughout their environment is thoughtto strongly influencepopulation structure

this germination behaviorhas influencedpopulation structure

current and historical landscapes(passive) influenced bypopulation structure

http://dx.doi.org/10.3732/ajb.1200614 •Premise of the study : Sprouting in woody plants promotes persistence in the face of disturbanceultimately influencingpopulation structure

lactate affinity and dissolved sulphide concentration(passive) was influenced bypopulation structure

an initial round of PCAto discoverpopulation structure

Migrationslargely influencedpopulation structure of Temerin

the major factorinfluencingpopulation structure

both the outcome of interactions and where insects feedmay influencepopulation structure

the hierarchical choice of accessions , which might otherwise produce false - positive associations(passive) caused bypopulation structure

the impact of non random mating and subsequent selection(passive) caused bypopulation structure

the primary mechanismscreatingpopulation structure

No other landscape featuresinfluencedpopulation structure

landscape disturbanceinfluencespopulation structure

differing ancestries(passive) created bypopulation structure

to spurious associations ( duhcan leadto spurious associations ( duh

spurious associations in GWAScan causespurious associations in GWAS

potential spurious associations(passive) caused bypotential spurious associations

spurious associations between markers and the trait under studycan causespurious associations between markers and the trait under study

to spurious associations between a candidate marker and a phenotypecan leadto spurious associations between a candidate marker and a phenotype

spurious associations of genetic variantscausesspurious associations of genetic variants

to spurious associations ( Price et al .leadsto spurious associations ( Price et al .

spurious associations of gene - by - environment interactionsmay causespurious associations of gene - by - environment interactions

spurious associations between markers and phenotypes ... 37may causespurious associations between markers and phenotypes ... 37

guidelines for specific human behaviors , especially intergroup relations.[10createdguidelines for specific human behaviors , especially intergroup relations.[10

guidelines for specific human behaviors , especially intergroup relations.[11createdguidelines for specific human behaviors , especially intergroup relations.[11

guidelines for specific human behaviors ... especially intergroup relations.[4createdguidelines for specific human behaviors ... especially intergroup relations.[4

from individual survival , dispersal , and reproductionresultingfrom individual survival , dispersal , and reproduction

arbitrarily high false - positive ratescan causearbitrarily high false - positive rates

false - positive association tests in European Americans ... 26can createfalse - positive association tests in European Americans ... 26

guidelines for specific human behaviors ... 98 27 Z M 12createdguidelines for specific human behaviors ... 98 27 Z M 12

guidelines for specific human behaviors ... the best way is to ask the employeescreatedguidelines for specific human behaviors ... the best way is to ask the employees

false positive associations in GWAScausesfalse positive associations in GWAS

genealogical patternsinfluencesgenealogical patterns

in genomewide patternsresultsin genomewide patterns

from both IBD and driftresultingfrom both IBD and drift

to false positives in the analysiscan leadto false positives in the analysis

can not only lower false - positives(passive) influenced bycan not only lower false - positives

in false associations between markers and traitscan resultin false associations between markers and traits

confounding in such studies [ 2,3might causeconfounding in such studies [ 2,3

only a small proportion of the phenotypic variation in the present studycontributesonly a small proportion of the phenotypic variation in the present study

genetic asymmetries between partners whereby the relatedness ( defined relative to the neighbourhood ) of an individual i to a partner j will differ from the relatedness of j to i. Here ... we introduce a widespread mechanism of kin recognition to a model of dispersal in subdivided populationscan causegenetic asymmetries between partners whereby the relatedness ( defined relative to the neighbourhood ) of an individual i to a partner j will differ from the relatedness of j to i. Here ... we introduce a widespread mechanism of kin recognition to a model of dispersal in subdivided populations

unexpected LDcould createunexpected LD

spurious LD(passive) caused byspurious LD

in false positives in outlier testscan also resultin false positives in outlier tests

possible statistical bias(passive) caused bypossible statistical bias

the degree of bias in GWAS(passive) caused bythe degree of bias in GWAS

from both drift and new mutationresultingfrom both drift and new mutation

confounding and lead to an elevated false - positive ratecan causeconfounding and lead to an elevated false - positive rate

a genetic covariance matrix K that accounted for confounding(passive) was caused bya genetic covariance matrix K that accounted for confounding

in a systematic bias that produces false - positive associations if not accounted for in association analyses ( Hirschhorn and Daly 2005can resultin a systematic bias that produces false - positive associations if not accounted for in association analyses ( Hirschhorn and Daly 2005

patterns consistent with no or little recombinationcreatespatterns consistent with no or little recombination

spurious GEI associations because inflation factors on GEI statistics are on average greater than onemay causespurious GEI associations because inflation factors on GEI statistics are on average greater than one

from the hierarchical selection of accessions , which may otherwise create false - positive associationsresultingfrom the hierarchical selection of accessions , which may otherwise create false - positive associations

in allele frequency differences between subpopulationsresultsin allele frequency differences between subpopulations

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