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Qaagi - Book of Why

Causes

Effects

a cytokine storm induced by monocytes and dendritic cells during dengue virus ( DENV ) replication(passive) can be caused byPlasma leakage / hemorrhages

increased capillary permeability(passive) is caused byPlasma leakage

a substantial increase in endothelial permeability that is mainly due to loosening of interendothelial junction and focal adhesion due to host ’s response to infectious pathogens(passive) is caused byPlasma leakage

a floating seal with a rubber ringto preventplasma leakage

the action of circulating mediators on the vascular endothelium ... and that the host immune response is a critical determinant of this response(passive) is caused byplasma leakage in dengue hemorrhagic fever

More ) J J Bowden , Peter Baluk , P M Lefevre , Steven R Vigna , Donald Mcdonald Substance P released from sensory nerve fiberscausesplasma leakage

while maintaining tight appositionto preventplasma leakage

endothelial cell dysfunction(passive) caused byplasma leakage

increased vascular permeability(passive) caused byplasma leakage

the onset of dengue fever in an individual which can develop into the more severe form of dengue hemorrhagic fevercausesplasma leakage

a variety of stimuli(passive) caused byplasma leakage

a novel therapeutic interventionto preventplasma leakage in dengue

More ) J J Bowden , Adella M Garland , +5 authors Donald Mcdonald Substance P ( SPcan causeplasma leakage

orderto preventplasma leakage

The apoptosis of microvascular endothelial cellscausesplasma leakage

However , caveolin-1 regulates VEGF - induced VEGFR2 autophosphorylation that is followed by downstream signaling [ 14may triggerplasma leakage

histamine , bradykinin , platelet - activating factor or(passive) caused byplasma leakage

to shock ( dengue shockmay leadto shock ( dengue shock

to a state of shock and respiratory distressmay leadsto a state of shock and respiratory distress

to a sudden onset of shock around the time of defervescencemay leadto a sudden onset of shock around the time of defervescence

to shock and fluid accumulation with ... without respiratory distress ... severe bleeding , or severe organ impairmentmay leadto shock and fluid accumulation with ... without respiratory distress ... severe bleeding , or severe organ impairment

in shock , accumulation of fluid , severe bleeding , respiratory distress , and organ impairment.4,5resultingin shock , accumulation of fluid , severe bleeding , respiratory distress , and organ impairment.4,5

in fluid in the abdomen and lungsresultingin fluid in the abdomen and lungs

low platelet counts [ 25 ] that is below 100,000 / mm3 within 1–2 days of infection andcauseslow platelet counts [ 25 ] that is below 100,000 / mm3 within 1–2 days of infection and

the skin(passive) caused bythe skin

severe internal dehydrationcausessevere internal dehydration

More commonly(passive) is caused byMore commonly

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