to the more serious form of gum disease called periodontitiscan leadto the more serious form of gum disease called periodontitis
increased bone marrow antibody productioncauseincreased bone marrow antibody production
swollen gums(passive) caused byswollen gums
to periodontitiscan leadto periodontitis
in bone pain and fracturesresultsin bone pain and fractures
to inflammation and damaged bone and tissueleadsto inflammation and damaged bone and tissue
to oral diseasecan ... leadto oral disease
to degradation of the tissue surrounding teethleadsto degradation of the tissue surrounding teeth
bacteria 21 % more than brushing alonecausingbacteria 21 % more than brushing alone
from monoclonal proliferation of plasma cellsresultfrom monoclonal proliferation of plasma cells
fatigue and frequent infectionsmay causefatigue and frequent infections
as the primary manifestation of the diseasecan originateas the primary manifestation of the disease
to immunoglobulin proteinleadto immunoglobulin protein
to immunoglobulin protein AAleadto immunoglobulin protein AA
to inflamed gumsleadsto inflamed gums
to end - organ damageleadingto end - organ damage
a wide variety of complications leading to organ dysfunction and eventually deathcausinga wide variety of complications leading to organ dysfunction and eventually death
from clonal expansion ofresultfrom clonal expansion of
in PPs and possibly other sites of B cell activationoriginatein PPs and possibly other sites of B cell activation
in the overproduction of clonal malignant plasmaresultsin the overproduction of clonal malignant plasma
gums to swell and become redcausesgums to swell and become red
the amount of bone loss(passive) caused bythe amount of bone loss
bad breath , ulcers and fevercausesbad breath , ulcers and fever
to the teeth becoming loose as the gum line separates from the tooth itselfcan leadto the teeth becoming loose as the gum line separates from the tooth itself
reinfectionscan causereinfections
allergic or anaphylactic reactions in some patientscould causeallergic or anaphylactic reactions in some patients