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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

also contains a pleckstrin homology domain that binds directly to PtdIns(3,4,5)P3 and PtdIns(3,4)P2causingPtdIns(3,4)P2to also translocate to the plasma membrane upon PI3 K activation

PIP2 ) hydrolysisleadsto intracellular Ca2 + release and activation of plasma membrane Ca2 + entry channels

Attacks of hereditary angioedemaresultfrom contact , complement , and fibrinolytic plasma cascade activation , where C1 esterase inhibitor irreversibly binds substrates

this effect ... Ca2+]iresultsfrom the activation of CaV1.3 L - type Ca2 + channels and Ca2

the signaling mechanismsleadingto activation ( and inactivation ) of red cell adhesion molecules

Exposure of blood to artificial materials in the bypass pumpcan causecontact activation of plasma coagulation , complement and inflammatory cascades

a materialdesignedto obtain bonding by covalent bonds activated by a plasma treatment

the extracellular domain of NOTCH1leadto ligand independent receptor cleavage and activation

depletion of intracellular Ca2 + storescausesthe activation of plasma membrane Ca2 + channels

Ca2 + release from the ERcausesthe activation of STIM 1 and 2 , which oligomerize and translocate to ER - plasma membrane junctions

storescausesthe activation of plasma membrane Ca2 + channels

an interface ... SV confinementleadsto the appropriate pairing of molecules mediating the fusion between the vesicles and the plasma membrane

confirmed by Lucovsky , argon initiates a different fragmentation of the silanethereby causingplasma polymerization of SiH2 and silane to disilane , trisilane , etc

a heterogeneous class of lipidscontributeto plasma membrane and plasma lipoprotein formation

Raft nanodomainscontributeto Akt / PKB plasma membrane recruitment and activation

Raft nanodomainscontributeto Akt / PKB plasma membrane recruitment and activation

KATP ) channelscausingplasma membrane depolarisation and influx of Ca2

dysfunction ( leakiness ) of pulmonary capillariescausesalveolar oedema and neutrophil activation

Ca2]ileadsto the activation of plasma membrane associated

that nebulizedcausesactivation of plasma renin and angiotensin II

Phosphorylation of Ser311 by Extracellular Signal - Regulated Kinase ( ERK ) , reversed by PP2Acausesplasma membrane targeting and activation of SPHK1

by the inductive(passive) caused bya plasma ... coupling and a plasma caused by the capacitive coupling

However , as reported from work done by Matsuda , et al , and confirmed by Lucovsky , argon initiates a different fragmentation of the silanecausingplasma polymerization of SiH2 and silane to disilane , trisilane , etc

thrombus formationcausesthrombus formation

in synergic effectsresultin synergic effects

to reduced thrombus formationleadsto reduced thrombus formation

to fibrin formationwill leadto fibrin formation

in blood clot formation ( 26resultsin blood clot formation ( 26

to inflammationleadingto inflammation

the cell to repair itself after injurycausingthe cell to repair itself after injury

coagulation disorders(passive) caused bycoagulation disorders

blood coagulation and thrombosis(passive) caused byblood coagulation and thrombosis

in renal cell death and necrosisresultingin renal cell death and necrosis

its cellular localizationinfluencesits cellular localization

to the creation of highly adhesivecontributedto the creation of highly adhesive

myocardial infarctioncan causemyocardial infarction

the physiological signaling pathways(passive) are ... influenced bythe physiological signaling pathways

to the lysis of specific cells in the absence of antibody on the cell surfaceleadsto the lysis of specific cells in the absence of antibody on the cell surface

in RGC deathresultsin RGC death

an area of continuing research C. EGF signaling(passive) is set ... byan area of continuing research C. EGF signaling

the coil(passive) caused bythe coil

the permeability of the endotheliuminfluencesthe permeability of the endothelium

to rapid occlusion of the aperture and cessation of blood flowleadingto rapid occlusion of the aperture and cessation of blood flow

unproductive loss of CO to blood haemoglobinwould causeunproductive loss of CO to blood haemoglobin

to blood to clotleadto blood to clot

C ) systemleadsC ) system

to altered Ca2 + signalingleadingto altered Ca2 + signaling

that thrombus(passive) caused bythat thrombus

to the production of the vasoactive peptide bradykininleadsto the production of the vasoactive peptide bradykinin

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Smart Reasoning:

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