the best peak shapes ... highly active or difficult compoundscausepeak tailing
secondary interactions between an analyte and the columnmay causepeak tailing
undesirable adsorption of basic or polar moleculesmay causepeak tailing
adsorption to tubing(passive) caused bypeak tailing
Basic , polar analytes analysed using Type I and Type II silica Mobile phase pH will affect the degree of silanol ionisation and therefore the degree with which they interact with polar and ionisable analytescausingpeak tailing
The ionized silanol ... cation - exchange modecausespeak tailing
unwanted secondary interactions with active sites within the liner , packing material or inlet seal(passive) caused bypeak tailing
non - specific interactions(passive) caused bypeak tailing
Insufficient buffering of mobile phase Insufficient buffer concentration ... increased secondary interactionscausepeak tailing
adsorption or extracolumn band broad - ening(passive) is typically caused byPeak tailing
The carboxylic acid ... the amine salt complex competes with active sites on the chiral columncan causepeak tailing
The scattering process also normally broadens chromatography peaks ,causingpeak tailing
The fittings seal the tubing connection in such a way that minimizes dead volume helpsto preventpeak tailing
dead volume in joints ... helpspreventpeak tailing
The presence of highly active silanol sitescan causepeak tailing
radial temperature gradientcan ... causepeak tailing
The end - capped silica gel , however , retains more or less silanol groups unchangedcausingpeak tailing
that has high metal - affinityto causepeak tailing
basic side chains ... free silanolscausepeak tailing
their binding to free silanolscausepeak tailing
the large amount of triclosan in the column(passive) caused bypeak tailing
the secondary interactioncausespeak tailing
trace metal contaminantscan causepeak tailing
the reaction between the components to be tested and the acidic silanol groups(passive) caused bythe peak tailing
heavy metals that were thoughtto causepeak tailing
chemical issues(passive) caused byPeak tailing
a large C(7.0 ... activated silanolscausepeak tailing
This procedure ... an increase in hydroxyl groups on the glass or silicate surfaceswill ... causepeak tailing
the subsequent build custom forex systems with c tion of analytes ... helpspreventpeak tailing
Aluminium , iron and lead are particularly problematiccausepeak tailing
other extra - column frits(passive) caused bypeak tailing
Column packing problemscan causepeak tailing
All threecan causepeak tailing
Preheat ... helpspreventpeak tailing
activity within the GC system and how to take preventative measures to minimize tailing and maximize sensitivity and area reproducibility(passive) caused bypeak tailing
's understandcausespeak tailing
of the mobile phase was adjusted to 3.6 with triethylamine for better resolution andto preventpeak tailing
with which the silica surface may potentially interact with polar and ionisable analytescausingpeak tailing
issuescreateissues
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Most of the time(passive) is causedMost of the time
to poor quantitation resultscan leadto poor quantitation results
to decreased sensitivityleadingto decreased sensitivity
from penetration of the analyte molecule deep into the silica matrixresultedfrom penetration of the analyte molecule deep into the silica matrix
from a combination of the programme materialresultingfrom a combination of the programme material
from collection of particles at the inlet fritresultingfrom collection of particles at the inlet frit
to a contamination with lower oligomers that increased with the degree of oligomerization ... and because of increasing contamination with unidentified aliphatic material from the nonpolar solvent and/or columnledto a contamination with lower oligomers that increased with the degree of oligomerization ... and because of increasing contamination with unidentified aliphatic material from the nonpolar solvent and/or column