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Qaagi - Book of Why

Causes

Effects

susceptibility genescontributingto familial Parkinson disease , Hum

his lab ... knownto causefamilial Parkinson ’s disease

mutations that are knownto causefamilial Parkinson 's disease

six known genescausefamilial Parkinson 's disease

The human gene parkin , knownto causefamilial Parkinson disease

The mutated forms of PINK1 and Parkin are knownto causefamilial Parkinson ’s Disease

the A53 T α - synuclein mutation , Exp(passive) caused byfamilial Parkinson 's disease

the A53 T [ alpha]-synuclein mutation , ” Experimental Neurology(passive) caused byfamilial Parkinson 's disease

Mutations in alpha - synuclein are knownto causefamilial Parkinson 's disease

19781641 LRRK2 ... in whichcausefamilial Parkinson 's disease

a mutation in the gene that codes for the protein alpha synuclein ( SNCAleadsfamilial Parkinson ’s disease

a mutation in one of their genes(passive) is caused byfamilial Parkinson ’s disease

mutations in either PINK1 or parkin(passive) can be caused byFamilial Parkinson ’s disease

Full TextThe α - synucleinA53 T mutationcausesfamilial Parkinson ’s disease

mutations in one of the human Roco genes ( LRRK2causefamilial Parkinson disease

Mutations in the genes coding for these proteinscausefamilial forms of Parkinson disease

authors Junpeng Deng LRRK2 ... in whichcausefamilial Parkinson 's disease

the loss of function mutations in the PD genes(passive) caused byfamilial Parkinson 's disease

the discovery of autosomal dominant mutations in LRRK2causingfamilial Parkinson ’s disease

the pathogenesis of Parkinson disease with mutations in mitochondrial - associated proteins such as PINK1 and parkincausingfamilial Parkinson disease

the mitochondrial kinase PINK1 and the E3 ubiquitin ligase PARK2 / Parkin ... whose mutationscausefamilial Parkinson disease

mutations in the LRRK2 , PARK7 , PINK1 , PRKN , or SNCA gene(passive) can be caused byFamilial cases of Parkinson disease

mutations in the LRRK2 , PARK2 , PARK7 , PINK1 , or SNCA gene(passive) can be caused byFamilial cases of Parkinson disease

the mitochondrial serine / threonine - protein kinase PINK1 and the E3 ubiquitin - protein ligase parkin ... whose mutationscausefamilial Parkinson ’s disease

mutations in the LRRK2 , PARK7 , PINK1 , PRKN , MAPT , GBA or SNCA gene(passive) can be caused byFamilial cases of Parkinson disease

Graham Stuart Jackson Yongchao Li , Laura Dunn , Elisa Greggio , Brian Krumm , Graham S Jackson , Mark R Cookson , Patrick A Lewis , Junpeng Deng LRRK2 ... in whichcausefamilial Parkinson 's disease

Full Text Cloning of the Gene Containing MutationsCausePARK8-Linked Parkinson 's Disease FAMILIAL

gene dosage effects of SNCAcan causefamilial Parkinson disease ( PD

mutations in the gene that produces this proteincan causefamilial Parkinson 's disease

Çekkin particular type of genecausesfamilial Parkinson 's disease

Several gene mutations have been shownto causeParkinson ’s disease in a few families

possessing extra copies of the normal AS genecan causefamilial Parkinson ’s disease

early - onset Alzheimer ’s disease , and duplications of alpha - synuclein ( SNCAcausefamilial Parkinson ’s disease

One genetic mutationresultingin familial Parkinson ’s Disease

the germline mutationscausingfamilial Parkinson 's disease

mutations in α - synucleincan causefamilial Parkinson 's disease

locus duplicationcausesfamilial Parkinson ’s disease

publications ... that were thoughtto causefamilial Parkinson 's disease

mutations in the NR4A2 locus(passive) caused byfamilial Parkinson 's disease

in many cases(passive) is causedFamilial Parkinson 's disease

a foundation for legal , financial and medical planningcreatea foundation for legal , financial and medical planning

mutant alpha - synucleincausesmutant alpha - synuclein

Lewy neurites(passive) caused byLewy neurites

depletionleadsdepletion

muscle tremors and difficult motor controlcausesmuscle tremors and difficult motor control

up especially for people who may be fit for work in the futurewas setup especially for people who may be fit for work in the future

patients to gradually lose fine motor skills due to hand tremourscausespatients to gradually lose fine motor skills due to hand tremours

LRRK2 mutation I2020 T is associated with increased kinase activitycausingLRRK2 mutation I2020 T is associated with increased kinase activity

hand shakes(passive) caused byhand shakes

from : destruction of dopamine - secreting neurons depression of voluntary motor control drugs used to increase dopamine production induceresultsfrom : destruction of dopamine - secreting neurons depression of voluntary motor control drugs used to increase dopamine production induce

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