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Qaagi - Book of Why

Causes

Effects

mutations in the LRRK2(passive) can be caused byFamilial cases of Parkinson disease

mutations in mitochondrial - associated proteins such as PINK1 and parkincausingfamilial Parkinson disease

Several genescausingfamilial Parkinson s disease

the accumulation of mutant alpha - synuclein proteinscausesfamilial Parkinson?s disease

LRRK2 mutationscausefamilial Parkinson disease

susceptibility genescontributingto familial Parkinson disease

medications(passive) is caused byDyskinesia in Parkinson disease

Several genescausingfamilial Parkinsons disease

by mutations(passive) is causedfamilial Parkinsons disease

mutationscausefamilial Parkinsons disease

Mutations in PINK1 have been shownto causefamilial cases of Parkinson 's disease

GenesinfluencingParkinson disease onset

by PINK1 or Parkin mutations(passive) is causedfamilial Parkinson 's disease ( PD

whose mutationscausefamilial Parkinson 's disease ( PD

Mutations in DJ-1causefamilial Parkinson 's disease ( PD

mutations in the alpha - synuclein genecan causeParkinson disease

Mutations in the human LRRK2 genecan causeParkinson disease

the death of cells that secrets dopamine in the brain(passive) is caused byParkinson disease

genescausefamilial Parkinson 's disease ( PD

Loss of dopamine cellscausesParkinson disease

decreased dopamine production in the brain(passive) is caused byParkinson disease

new genescauseParkinson disease

deficiency of a chemical called dopamine in the brain(passive) is caused byParkinson disease

mutationscausingParkinson disease

the lack of dopaminecausesParkinson disease

dopamine neuronscausingParkinson disease

Deterioration of nerve cells in the braincausesParkinson disease

which is knownto causeParkinson disease

the proteincausingParkinson Disease

a loss of dopaminergic neurons(passive) is caused byParkinson disease

several SNCA mutationscauseParkinson disease

several SNCA mutations ... , butcauseParkinson disease

the progressive degeneration of dopamine brain cells(passive) is caused by Parkinson disease

GenesCauseParkinson Disease

GenesinfluencingParkinson disease

genescausingParkinson disease

due to deficiency of A(passive) is causedParkinson disease

the prion - like spread of the mis - folded protein alpha - synuclein(passive) is caused byParkinson disease

pink1 / parkin mutations(passive) caused byParkinson disease

these stem cells ... the lack of dopaminecausesParkinson disease

difficulty primarily with walkingcausesdifficulty primarily with walking

in tremorto resultin tremor

patients to gradually lose fine motor skills due to hand tremourscausespatients to gradually lose fine motor skills due to hand tremours

a progressive decline in movement controlcausesa progressive decline in movement control

to shaking ( tremorsleadsto shaking ( tremors

from the death or loss of dopamine producing brain cells which are important in brain signal transmissionresultsfrom the death or loss of dopamine producing brain cells which are important in brain signal transmission

tremor , rigiditycan causetremor , rigidity

to problems in movement andcan leadto problems in movement and

to tremorsleadsto tremors

rigidity , tremors , and other motor symptomscausesrigidity , tremors , and other motor symptoms

problems such asmay causeproblems such as

alsocausesalso

alsocausedalso

Pain in SpinecausingPain in Spine

4 characteristic problems(passive) caused by4 characteristic problems

certain brain cells to diecausescertain brain cells to die

certain brain cells to diecausescertain brain cells to die

oftenleadsoften

oftencausesoften

tremors(passive) caused bytremors

changes in the brain that lead to depressionmay ... causechanges in the brain that lead to depression

changes in the brain that lead to depressionmay also causechanges in the brain that lead to depression

Tremors ( shaking(passive) caused byTremors ( shaking

brain damage(passive) normally caused bybrain damage

from degenerationresultsfrom degeneration

from a deficiency of whatresultsfrom a deficiency of what

various non - motor problems that have significant physical and emotional impacts on patients and their familiescan causevarious non - motor problems that have significant physical and emotional impacts on patients and their families

sometimesleadssometimes

primarilyresultsprimarily

uncontrolled shaking movementscausesuncontrolled shaking movements

from certain brain cells dyingresultsfrom certain brain cells dying

from certain brain cells dyingresultsfrom certain brain cells dying

physical symptoms at firstcausesphysical symptoms at first

to a decline in brain function and early deathmay leadto a decline in brain function and early death

to his early deathledto his early death

for sharing with patientsdesignedfor sharing with patients

Constipation(passive) caused byConstipation

shaking or tremorcausesshaking or tremor

slowness in movementsalso causesslowness in movements

Tremors that occur during rest(passive) are often caused byTremors that occur during rest

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