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Smart Reasoning:

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Qaagi - Book of Why

Causes

Effects

Several genescausingfamilial Parkinsons disease

mutationscausePARK8-linked Parkinsons disease

by the loss of cells that are responsible for producing dopamine in the brain(passive) is caused byParkinson?s disease

by a lack of the chemical dopamine in the brain(passive) caused byParkinson?s disease

by a lack of the chemical dopamine in the brain(passive) is caused byParkinson?s disease

because of the loss of a specific neuron known as dopaminergic neurons which are responsible for producing a natural chemical dopamine(passive) is caused Parkinson?s disease

from the death of dopamine - containing cells in a specific part of the brain called the substantia nigra(passive) is causedParkinson?s disease

loss of brain cells in a specific region of the brain called the substantia nigra(passive) is caused byParkinson?s disease

the effects of mutations knownto causeParkinson?s disease

mutations are knownhow ... to causeParkinson?s disease

how mutations are knownto causeParkinson?s disease

a lack of dopamine in the brain(passive) is caused byParkinson?s disease

a gene and proteincausesParkinson??s disease

by the death of specific nerve cells in the brain(passive) caused byParkinson?s disease

Mutations in the LRRK2 genecan causeParkinson?s disease

Mutations in the LRRK2 genecan causeParkinson?s disease

mutations in the vps35 genecauseParkinson?s disease

mutations in the Vps35 genealso causeParkinson?s disease

neurons in Parkinson?s disease ... reduced mitochondrial stressmight causeParkinson?s disease

Several researchers ... certain genetic mutationscan causeParkinson?s disease

a deficiency in the brain of the neurotransmitter dopamine(passive) is caused byParkinson?s disease

by a decline in a brain neurotransmitter called dopamine(passive) is caused byParkinson?s disease

the deterioration of neurons in an area deep in your brain called the substantia nigra(passive) is caused byParkinson?s disease

Lack of dopamine neurotransmitter in the braincausesParkinson?s disease

the damage ... to two structures deep in the braincausesParkinson?s disease

loss of brain cells in a specific region of the brain(passive) is caused byParkinson?s disease

a cascade of chemical events in the braincould leadto Parkinson?s Disease

by low levels of dopamine in the brain(passive) caused byParkinson?s disease

The presence of specific toxins in the environmentcould causeParkinson?s disease

a human genecausesParkinson?s disease

brain cells from the inflammation knownto causeParkinson?s disease

due to dopamine deficiency(passive) is causedParkinson?s disease

certain toxins in the environmentmay causeParkinson?s disease

However , it?s not knowncausesParkinson?s disease

by the death of dopamine - producing neurons(passive) is caused byParkinson?s disease

by a combination of genes and environment(passive) is caused byParkinson?s disease

by a lack of dopamine in the brain that causes brain activity to function normally(passive) is caused byParkinson?s disease

a lack of dopamine in the brain that causes brain activity to function normally(passive) is caused byParkinson?s disease

the deterioration of nerve cells in a region of the brain called the substantia nigra(passive) is caused byParkinson?s disease

a degeneration of dopamine neurons in an area of the midbrain known as the substantia nigra , which is responsible for dopamine production(passive) is caused byParkinson?s disease

overactivity of deep - seated nuclei of braincausesoveractivity of deep - seated nuclei of brain

tremors , stiffness and troublecan causetremors , stiffness and trouble

a progressive decline in movement controlcausesa progressive decline in movement control

progressive problems with movement , posture and balancecausesprogressive problems with movement , posture and balance

symptoms and treatmentcausessymptoms and treatment

from the loss of the dopamine - producing brain cells that control movementresultsfrom the loss of the dopamine - producing brain cells that control movement

patients to have problems with starting a movementcausingpatients to have problems with starting a movement

depression , as well ascan causedepression , as well as

both financial and emotional distress to its victims and their familiescausesboth financial and emotional distress to its victims and their families

motor problems , tremors , and difficulty with speechcausesmotor problems , tremors , and difficulty with speech

Causes and Symptoms(passive) is ... causedCauses and Symptoms

both non - motor and motor symptomscausesboth non - motor and motor symptoms

death of these nerve cellscausesdeath of these nerve cells

his deathwould ... causehis death

deathwill causedeath

to deathcan leadto death

stiffness in muscles , tremors , and difficulties in movementcausesstiffness in muscles , tremors , and difficulties in movement

the brain to produce less dopamine , which leads to a loss of movement controlcausesthe brain to produce less dopamine , which leads to a loss of movement control

these symptomscan causethese symptoms

neurons that produce dopamine in the brain to diecausesneurons that produce dopamine in the brain to die

from loss of dopamine neuronsresultsfrom loss of dopamine neurons

the death of dopamine - producing brain cellscausesthe death of dopamine - producing brain cells

from damageresultsfrom damage

alsomight causealso

alsomay ... resultalso

alsocan ... causealso

alsocould ... causealso

alsoleadsalso

to slow movementleadingto slow movement

from a lack of dopamine in the brainresultsfrom a lack of dopamine in the brain

motor symptoms such as tremor , rigidity , and slowness of movementscausesmotor symptoms such as tremor , rigidity , and slowness of movements

to a patient?s fatiguecan ... contributeto a patient?s fatigue

dementiacausesdementia

dementiacan causedementia

her to have dementiacausedher to have dementia

for some patientsmay causefor some patients

to motor disordersleadsto motor disorders

involuntary shaking and slow movementcausesinvoluntary shaking and slow movement

loss of dopamine - producing brain cellscausesloss of dopamine - producing brain cells

memory loss or dementiacausesmemory loss or dementia

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