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Qaagi - Book of Why

Causes

Effects

excessive thyroid hormonecan leadto an overactive metabolism

epigenetic and genetic factorsinfluencingthiopurine metabolism

an increase in the secretion of the thyroid hormonecan leadto an overactive metabolism

an overabundance of thyroid hormone ( called hyperthyroidismcan leadto an overactive metabolism

an over abundance of thyroid hormone ( called Hyperthyroidismcan leadto an overactive metabolism

to lead to excess of the other thyroid hormone , T3resultingin an overactive metabolism

in which the thyroid gland produces too much thyroid hormonecausingan overactive metabolism

Overactive thyroid glandleadsto overactive metabolism

serum apolipoprotein B Objective Carboxylesterases , which convert dabigatran etexilate to its active form , dabigatran , have also been shownto influencelipoprotein metabolism

apoC - III(passive) caused bylipoprotein metabolism

the energy needed to generate heat from brown fat , which might seem contradictory given their impaired thyroid hormone function(passive) caused byan overactive metabolism

mutations in the low - density lipoprotein receptor ( LDLR ) gene(passive) caused mainly bylipoprotein metabolism

mutations in the LPL and apolipoprotein ( apo(passive) caused bylipoprotein metabolism

how decreased SR - BI protein expressioninfluencedlipoprotein metabolism

interaction of a defect in apolipoprotein E with genetic and environmental factors causing hypertriglyceridemia(passive) caused bylipoprotein metabolism

St East , Hamilton , Ontario , Canada L8L 2X2 ; philip.joseph{at}phri.ca AbstractObjective Carboxylesterases , which convert dabigatran etexilate to its active form , dabigatran , have also been shownto influencelipoprotein metabolism

The study ... genes on these lociinfluencelipoprotein metabolism

The excess hormoneleadsto an overactive metabolism

mutations in the gene identified for this particular complementation group ( Fowler et al . , 2008(passive) caused bycobalamin metabolism

a greater potentialto influencelipoprotein metabolism

a 4th orderto createcontentOpen metabolism

hyperthyroidism ... the thyroid glandcausesan overactive metabolism

a deficiency of the lysosomal enzyme , -galactosidase A(passive) caused byglycolipid metabolism

in which the thyroid gland produces too much hormonecausingan overactive metabolism

particularly oxidative phosphorylation(passive) is ... influencedskhushu@yahoo.comAbstractMitochondrial metabolism

any medication knownto influencelipoprotein metabolism

any medications knownto influencelipoprotein metabolism

The relation ... knownto influencehomocysteine metabolism

These analyses ... knownto influenceclozapine metabolism

medicines knownto influencesirolimus metabolism

because ammonium is not knownto influencephosphoinositide metabolism

deficiency of the lysosomal enzyme alpha - galactosidase A.(passive) caused byglycolipid metabolism

Ellison Themeles1 , 4Department of Clinical Development and Clinical Biostatistics , Boehringer Ingelheim Pharmaceuticals , Ridgefield , Connecticut , USA Correspondence to Dr Philip G Joseph , Population Health Research Institute , C2 6A DB - CVSRI , 237 Barton St East , Hamilton , Ontario , Canada L8L 2X2 ; philip.joseph{at}phri.ca Objective Carboxylesterases , which convert dabigatran etexilate to its active form , dabigatran , have also been shownto influencelipoprotein metabolism

this book ... the renowned cancer researcherdiscoveredTKTL1 metabolism

deficiency of the hepatic enzyme glyoxylate reductase / hydroxypyruvate reductase ( GRHPR).7 Absence of GRHPR activity results in excess oxalate and usually L - glycerate excreted in the urine leading to kidney stones and sometimes kidney failure(passive) caused byglyoxylate metabolism

mutations in the lcat[icd10data.com ] HL deficiency hyperlipidemia due to hepatic triglyceride lipase deficiency LIPC deficiency Chatterjee C(passive) caused bylipoprotein metabolism

a recent study we performed in which we discovered an epigenetic mechanism in PAH that was downregulating the expression of the mitochondrial calcium uniporter ( MUCU ) , leading to calcium overload in the cytosol ( causing vasoconstriction ) and calcium depletion in the mitochondriacausingWarburg metabolism

a deficiency in the liver - specific peroxisomal enzyme known as alanine glyoxylate aminotransferase ( AGT(passive) caused byglyoxylate metabolism

rest disorderly ... air conditioncausedisorder metabolism

other potential susceptibility genes ... many of whichmay influenceAβ metabolism

with increased blood concentrations of the lattermay causewith increased blood concentrations of the latter

DNA damage and triggers a breast cancer - related DNA damage response The Future of Genetic PrivacycausesDNA damage and triggers a breast cancer - related DNA damage response The Future of Genetic Privacy

DNA damage and triggers a breast cancer - related DNA damage response Autism and Human Evolutionary SuccessArchivescausesDNA damage and triggers a breast cancer - related DNA damage response Autism and Human Evolutionary SuccessArchives

homocystinuriacausinghomocystinuria

in elevated serum low density lipoprotein ( LDL ) cholesterol levels leading to increased risk for premature cardiovascular diseases ( CVDsresultingin elevated serum low density lipoprotein ( LDL ) cholesterol levels leading to increased risk for premature cardiovascular diseases ( CVDs

to hypercholesterolemialeadingto hypercholesterolemia

to diabetes , lipid disorders , obesity , and insulin resistance – all common , modern scourgescontributesto diabetes , lipid disorders , obesity , and insulin resistance – all common , modern scourges

from increased serum concentration of T4 and/or T3resultingfrom increased serum concentration of T4 and/or T3

to formation of sugar - derived metabolic intermediates and generation of ROS and apoptosis under normal conditions glucoseleadingto formation of sugar - derived metabolic intermediates and generation of ROS and apoptosis under normal conditions glucose

all sorts of havoc internallyis causingall sorts of havoc internally

to toxic metabolite Isoniazid Ketoconazole Troglitazone Elevated LFTs , acute hepatitis , jaundice Low ( unpredictableleadingto toxic metabolite Isoniazid Ketoconazole Troglitazone Elevated LFTs , acute hepatitis , jaundice Low ( unpredictable

to Clinicians 's presence in a particular patientcontributingto Clinicians 's presence in a particular patient

in decreased MeCbl andresultingin decreased MeCbl and

abiraterone metabolism 's own competitor ... in a manner of speakingcreatesabiraterone metabolism 's own competitor ... in a manner of speaking

in elevated serum levels of low - density lipoprotein cholesterol ( LDL - C ) , which lead to increased risk for premature cardiovascular diseaseresultingin elevated serum levels of low - density lipoprotein cholesterol ( LDL - C ) , which lead to increased risk for premature cardiovascular disease

in obesity or trouble gaining weightresultsin obesity or trouble gaining weight

in excessive weight loss , inability to sleep , and high levels of anxietyresultsin excessive weight loss , inability to sleep , and high levels of anxiety

rapid weight loss , hair loss , insomnia , restlessness and hyperactivitycausingrapid weight loss , hair loss , insomnia , restlessness and hyperactivity

significantly to the resistance in Palmer amaranthis contributingsignificantly to the resistance in Palmer amaranth

symptoms such as excessive sweating , weight loss , heart problems , and sensitivity to heatcausessymptoms such as excessive sweating , weight loss , heart problems , and sensitivity to heat

to heart palpitations , insomnia , fast heart rate , weight loss and other symptomsleadsto heart palpitations , insomnia , fast heart rate , weight loss and other symptoms

to decreased availability of monoamine neurotransmittersleadingto decreased availability of monoamine neurotransmitters

from nutritional deficiency , enzyme deficiency , abnormal secretion of hormones , or the actions of drugs and toxinsmay resultfrom nutritional deficiency , enzyme deficiency , abnormal secretion of hormones , or the actions of drugs and toxins

in decreased metabolism of the amino acid phenylalanineresultsin decreased metabolism of the amino acid phenylalanine

people from using food for cellular energy at the mitochondrial levelpreventspeople from using food for cellular energy at the mitochondrial level

dyslipidemia ( defined as high levels of LDL and TG and low levels of HDL ) contribute to the pathogenesis of atherosclerosis , which is the underlying cause of CHDcausedyslipidemia ( defined as high levels of LDL and TG and low levels of HDL ) contribute to the pathogenesis of atherosclerosis , which is the underlying cause of CHD

the serials of symptoms in diabetic patients including overweight or obesity , unbalance of anabolism and catabolism in adipocyte , chronic inflammation which induced the insulin resistancecausedthe serials of symptoms in diabetic patients including overweight or obesity , unbalance of anabolism and catabolism in adipocyte , chronic inflammation which induced the insulin resistance

in abnormalities of blood - brain barrier function and a decreased ability to generate new intracellular osmotically active compounds ( osmolytes ) in response to osmotic changesresultingin abnormalities of blood - brain barrier function and a decreased ability to generate new intracellular osmotically active compounds ( osmolytes ) in response to osmotic changes

over - energized body which also leads to body ’s tiredness and fatiguemight causeover - energized body which also leads to body ’s tiredness and fatigue

to apoptosis of certain tissuesleadingto apoptosis of certain tissues

in increase in total cholesterol ( TCresultingin increase in total cholesterol ( TC

from hyperthyroidresultingfrom hyperthyroid

low stamina , low weight , high body heat , and frequent tirednesscausinglow stamina , low weight , high body heat , and frequent tiredness

in an emaciated stateoften resultingin an emaciated state

to the formation oonleadingto the formation oon

to increased uptake of glucose and its conversion to lactateleadingto increased uptake of glucose and its conversion to lactate

to LOAD pathogenesiscontributesto LOAD pathogenesis

to the formation of a large number of metabolites including such compounds as N - acetylserotonin , 5-methox- ytryptamine , methoxytryptophol , mink several kynurenamines , including N - acetyl- 5-methoxy - kynurenamine and N - acetyl-2-formyl-5-methoxy - kynurenamine ( 13,15,20leadingto the formation of a large number of metabolites including such compounds as N - acetylserotonin , 5-methox- ytryptamine , methoxytryptophol , mink several kynurenamines , including N - acetyl- 5-methoxy - kynurenamine and N - acetyl-2-formyl-5-methoxy - kynurenamine ( 13,15,20

to hyperlipidemia when regulatory T - cells are eradicatedleadingto hyperlipidemia when regulatory T - cells are eradicated

other cellular depletion(passive) caused byother cellular depletion

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