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Qaagi - Book of Why

Causes

Effects

Both conditionscausenormal anion gap metabolic acidosis and hypokalemia

acid produced by the body(passive) is typically caused byHigh anion gap metabolic acidosis

acid produced by the body(passive) is typically caused byAnion High anion gap metabolic acidosis

renal bicarbonate lossmay resultin a normal anion gap metabolic acidosis

Zonisamidecauseshyperchloremic , non - anion gap , metabolic acidosis

bicarbonatecontributesto a normal anion gap metabolic acidosis ( NAGMA

The loss of bicarbonate - rich fluid in severe diarrheamay causenon - anion gap metabolic acidosis

This is compensated by an increase in chloride concentrationthus leadingto a normal anion gap , or hyperchloremic , metabolic acidosis

Metabolic Acidosis Zonisamidecauseshyperchloremic , non - anion gap , metabolic acidosis

Loss of bicarbonate - rich pancreatic fluid via a pancreatic fistulacan resultin a hyperchloraemic or normal anion gap metabolic acidosis

healthcare professionalscauseshyperchloremic , non - anion gap metabolic acidosis

The loss of sodium induces volume depletion and the retention of administered sodium chloride , similar to the events after bicarbonate lossthereby causinga normal anion gap metabolic acidosis

byproductscausean elevated anion gap metabolic acidosis

conditionscauseacidosis with a normal anion gap

to resorb bicarbonate / secrete hydrogen ionsresultingin normal anion gap metabolic acidosis

a large hydrogen - ion loadcan causemetabolic acidosis with a raised anion gap

meaningcausesan elevated anion gap metabolic acidosis

Excessive loss of HCO3- in the gastrointestinal tractalso causesnormal anion gap acidosis

Ureteral diversioncan leadto normal anion gap acidosis

ketoacids(passive) is ... caused byan anion gap metabolic acidosis

toxic alcoholscausinganion gap metabolic acidosis

Lipolysis and alcohol metabolism generate ketoacidscausingan anion gap metabolic acidosis

A reduction in distal tubular proton secretion , in the absence of or out of proportion to reductions in GFRalso can leadto normal anion gap acidosis

a serum osmolal gapcausea serum osmolal gap

a serum osmolal gapcausea serum osmolal gap

non - anion gap metabolic acidosismay causenon - anion gap metabolic acidosis

potassium shiftcan also causepotassium shift

to increased oxygen deliveryleadsto increased oxygen delivery

increased / decreasedcan causeincreased / decreased

to coma and deathcan leadto coma and death

from ketoacid productionresultingfrom ketoacid production

from HCO3- losscan resultfrom HCO3- loss

from several different mechanismscan resultfrom several different mechanisms

in accelerated aging and other pathological conditions such as diabetes and heart diseaseresultin accelerated aging and other pathological conditions such as diabetes and heart disease

qualitative shifts in metabolism toother pathwaysmay causequalitative shifts in metabolism toother pathways

from the following sequence of events ... Metabolism of ingested food produces sulfuric , phosphoric , and organic acidsresultsfrom the following sequence of events ... Metabolism of ingested food produces sulfuric , phosphoric , and organic acids

to renal osteodystrophycontributesto renal osteodystrophy

their abnormal shape and inflexibility(passive) caused bytheir abnormal shape and inflexibility

to coma and deathcan leadto coma and death

multiple infarcts(passive) caused bymultiple infarcts

symptoms that might comprise of pains felt in the chest , abnormality in heartbeats , headaches , drowsiness , low energy levels , lost or heightened craving for food , decrease in sharpness of vision , change in mental condition like acute nervousness resulting from hypoxia , muscular weakness and pains in the bonecausessymptoms that might comprise of pains felt in the chest , abnormality in heartbeats , headaches , drowsiness , low energy levels , lost or heightened craving for food , decrease in sharpness of vision , change in mental condition like acute nervousness resulting from hypoxia , muscular weakness and pains in the bone

from either hematogenous dissemination of parasites anf and dna analysis abnormal cag insert in androgen receptor and plays a significant change in bowel habitsresultsfrom either hematogenous dissemination of parasites anf and dna analysis abnormal cag insert in androgen receptor and plays a significant change in bowel habits

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