a mutationcausesthree lysine residues on the third histone , H3K4 , H3K36 , and H3K79
targets WDR5 / MLL complexes across the HOXA locusleadingto histone H3 lysine 4 trimethylation ( H3K4me3 ) and gene transcription
as fixed and variable modifications(passive) were setCarbamidomethylation of cysteine and oxidation of methionine
a mutation ... a delay in the mitotic cell cyclecausesthree lysine residues on the third histone , H3K4 , H3K36 , and H3K79
as variable modifications(passive) were setCarbamidomethylation of cysteine and oxidation of methionine
histone - modifying enzymatic activitiesresultingin monoubiquitination at lysine 119 of histone H2A and methylation at lysine 27 of histone H3
as fixed and variable modifications(passive) were setCysteine carbamido methylation and methionine oxidation
diabetic conditions in human monocytes(passive) caused byhistone lysine methylation variations
by diabetic conditions in human monocytes(passive) caused byhistone lysine methylation variations
by diabetic conditions in human monocytes[J(passive) caused byhistone lysine methylation variations
diabetic conditions in human monocytes[J(passive) caused byhistone lysine methylation variations
the pathwayleadingto biosynthesis of lysine , threonine , methionine , cysteine and isoleucine
the aspartate pathwayleadsto the biosynthesis of lysine , methionine , threonine , and isoleucine
Swedish chemists(passive) have been discovered bynickel , manganese , molybdenum and nitrogen
the alteration of EZH2 and JMJD3 expression level by HDAC inhibitor treatmentcauseshistone lysine methylation
a protein peptidecomposedof glycine , histidine and lysine ( GHK
In particular , the function of hnRNPM may beto influencelysine sumoylation and arginine methylation
an alloycomposedof nickel , molybdenum and chromium
by chronic hypoxia(passive) caused byhistone acetylation and DNA methylation
by the solidification of material(passive) caused bynickel , molybdenum and chromium
the solidification of material(passive) caused bynickel , molybdenum and chromium
exposureto leadchromium , manganese and nickel
a protein peptidecomposedof glycine , histidine and lysine
Long - term exposureto leadchromium , manganese and nickel
an alloycomposedof nickel and chromium
Proteincontributeslysine methylation
an amino acidcomposedof lysine and methionine
five peptidescomposedof lysine , threonine and serine
activation ... and trimethylation of lysine 27 on histone 3 , which causes repression ( H3K27me3causesactivation ... and trimethylation of lysine 27 on histone 3 , which causes repression ( H3K27me3
in increased global acetylation and regulation of gene expressionresultingin increased global acetylation and regulation of gene expression
to transcriptional repressionleadsto transcriptional repression
to exceptional resistance to chloride stress corrosion crackingleadto exceptional resistance to chloride stress corrosion cracking
to activation or repression of gene transcriptioncan contributeto activation or repression of gene transcription
to production of carbonyl groups ( aldehyde and ketonesleadsto production of carbonyl groups ( aldehyde and ketones
to slowed growth and increased differentiationleadingto slowed growth and increased differentiation
to transcriptional regulationcontributeto transcriptional regulation
to transcriptional repressionleadingto transcriptional repression
to the blocking of transcriptional activation factors and thereby gene silencing independent of promoter methylationleadsto the blocking of transcriptional activation factors and thereby gene silencing independent of promoter methylation
gene silencingcausinggene silencing
alsomight ... contributealso
alsomight ... contributealso
to the pathogenesis of invasive candidiasiscontributesto the pathogenesis of invasive candidiasis
to apoptosisleadsto apoptosis
alsocan causealso
in a regulatory pattern that controls gene expressionresultingin a regulatory pattern that controls gene expression
to silencing of genes located near telomeresleadsto silencing of genes located near telomeres
to disrupt STAT3 dimerization and inhibit its transcription activityleadsto disrupt STAT3 dimerization and inhibit its transcription activity
to disrupt STAT3 dimerization and inhibit its transcription activity ( PubMed:28065600leadsto disrupt STAT3 dimerization and inhibit its transcription activity ( PubMed:28065600
cancercan causecancer
The epigenome(passive) is composedThe epigenome
either transcription activationcan leadeither transcription activation
of BRD2 , BRD3 , BRD4 , and BRDT and contain bromodomains that recognize acetylated lysine residues on histone tails [ 70 , 71are composedof BRD2 , BRD3 , BRD4 , and BRDT and contain bromodomains that recognize acetylated lysine residues on histone tails [ 70 , 71
in differentiation and induction of tumor suppressor genes such as p21WAF1 / CIP1 ... 17 18resultedin differentiation and induction of tumor suppressor genes such as p21WAF1 / CIP1 ... 17 18
in glycemic and insulinemic responsesresultedin glycemic and insulinemic responses
in glycemic and insulinemic response resembling the response seen after ingestion of wheyresultedin glycemic and insulinemic response resembling the response seen after ingestion of whey
pathophysiology of MSinfluencingpathophysiology of MS
The oxaloacetate / aspartate family of amino acids(passive) is composedThe oxaloacetate / aspartate family of amino acids
to the superior heat resistancecontributeto the superior heat resistance
asthmacan causeasthma
to the inactivation of a tumor suppressor genecontributesto the inactivation of a tumor suppressor gene
as fixed modifications ; and formylation , acetylation and heavy acetylation of N - termini ( Acetyl:2H(3)C13(2 ) ( N - term ) ) and pyroglutamate formation of N - terminal glutamine ( both at peptide level ) were set as variable modificationswere setas fixed modifications ; and formylation , acetylation and heavy acetylation of N - termini ( Acetyl:2H(3)C13(2 ) ( N - term ) ) and pyroglutamate formation of N - terminal glutamine ( both at peptide level ) were set as variable modifications
several fundamental cellular pathways including cell apoptosis , cellular differentiation , and metabolismcan influenceseveral fundamental cellular pathways including cell apoptosis , cellular differentiation , and metabolism