of two heavy chains and four light chains [ two regulatory ( LC20 ) and two essential ( LC17 ) light chains(passive) is composedMyosin
impulse travels into the myofibril via the transevere tubules and triggers the release of calcium ions from the sarcoplasmic reticulum at rest tropomyosin strandspreventmyosin
Tropmyosinpreventsmyosin
of light and heavy meromyosin and acts as an ATPase , hydrolyzing ATP(passive) is composedMyosin
Contraction of the actin network(passive) is caused byContraction of the actin network
contraction ... and attachment to the substrate via integrinstriggeredcontraction ... and attachment to the substrate via integrins
the hydrolysis of ATP and and dissociation of ADP from myosin resulting in the “ power stroke ” of contraction ( for a more detailed account check this outcausesthe hydrolysis of ATP and and dissociation of ADP from myosin resulting in the “ power stroke ” of contraction ( for a more detailed account check this out
contraction of muscle fibres , which causes movement in animalscausescontraction of muscle fibres , which causes movement in animals
to cross bridge cycling and contraction at the expense of ATP hydrolysisleadingto cross bridge cycling and contraction at the expense of ATP hydrolysis
to increased PKB signaling and decreased contraction ( 41 , 42 , 44leadingto increased PKB signaling and decreased contraction ( 41 , 42 , 44
the actin filaments to pull past each other causing a contraction ( sarcomeres , the basic unit of contraction , shortencausingthe actin filaments to pull past each other causing a contraction ( sarcomeres , the basic unit of contraction , shorten
to force production and filament slidingleadingto force production and filament sliding
The thick filament(passive) is composedThe thick filament
to the generation of resting cortical tensioncontributesto the generation of resting cortical tension
in force generation through actin - myosin interactionsresultingin force generation through actin - myosin interactions
to the force - velocity relationship of cardiac musclecontributeto the force - velocity relationship of cardiac muscle
in turn stimulates force - dependent maturation of focal adhesions [ 101resultsin turn stimulates force - dependent maturation of focal adhesions [ 101
from a further increase of myorod contentresultingfrom a further increase of myorod content
of an NH2-terminal domain typical of the globular , actin - binding domain of other myosinscomposedof an NH2-terminal domain typical of the globular , actin - binding domain of other myosins
mysoin to move - power stroke another ATp used to detach mysoin from actincausesmysoin to move - power stroke another ATp used to detach mysoin from actin
to restore the inadequate output characteristic of a DCM heart by targeting the biomechanical defects underlying disease and improving cardiac contractilitydesignedto restore the inadequate output characteristic of a DCM heart by targeting the biomechanical defects underlying disease and improving cardiac contractility
up [ 4setup [ 4
to increase cardiac contractility in a DCM heartdesignedto increase cardiac contractility in a DCM heart
myosin and actincausingmyosin and actin
adenosine triphosphate ( ATP ) to be broken down into adenosine diphosphate ( ADP ) and inorganic phosphate ( Pcausesadenosine triphosphate ( ATP ) to be broken down into adenosine diphosphate ( ADP ) and inorganic phosphate ( P
myosin to be released from actincausesmyosin to be released from actin
forces within these actin networks that can cause synapses to grow in one part of the brain or be destroyed in yet anothercreatesforces within these actin networks that can cause synapses to grow in one part of the brain or be destroyed in yet another
an autosomal dominant syndrome(passive) caused byan autosomal dominant syndrome
in elevation of all sensations 5resultingin elevation of all sensations 5
for examplecreatesfor example
to relaxation of muscleleadsto relaxation of muscle
in shortening of the muscle cell Microtubulesresultingin shortening of the muscle cell Microtubules
of myosin proteinsare composedof myosin proteins
alsocontributesalso
free energy(passive) caused byfree energy
to muscle necrosisleadingto muscle necrosis
to increase cardiac contractility for people with dilated cardiomyopathydesignedto increase cardiac contractility for people with dilated cardiomyopathy
in muscle relaxation b. Persistent attachment of actinresultingin muscle relaxation b. Persistent attachment of actin
in accumulation of fluid from a strokeresultingin accumulation of fluid from a stroke
of two intertwined strands of a protein called fibrous ( F ) actin - made of huge springy protein called titincomposed primarilyof two intertwined strands of a protein called fibrous ( F ) actin - made of huge springy protein called titin
mitral valve stenosiscausingmitral valve stenosis
of a pair of globular headscomposedof a pair of globular heads
to activation of the Arp2/3 complex , which promotes actin assembly at the phagocytic cup ( 100then leadsto activation of the Arp2/3 complex , which promotes actin assembly at the phagocytic cup ( 100