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to act as temporary valves and provide tight shut - off(passive) are designedTengxuan spindles
spindle pole amountscreatingmultipolar spindles
A loss of such a localised microtubule - stabilising activity at spindle polesmay causedestabilisation of spindles
defects in centrosome duplication , mitotic kinases , motor - dependent forces or microtubule(passive) can be caused byMonopolar spindles
either failure of mitosis or cytokinesis(passive) can be caused byMultipolar spindles
specially(passive) are ... designedHobbing Spindles
to spin short , fine fibers such as cotton or cashmere(passive) are specifically designedTahkli spindles
max per socketpaintedfinials spindles
during grinding the nut tightens on the wheel(passive) are designed so thatDumore spindles
Inhibition of PLK1causedmonopolar spindles
Kif2a depletion(passive) caused bymultipolar spindles
for increased strength , minimized weight , improved handling , and increased braking capacity on component cars , street rods , drag cars and other custom / competition applications using Ford Mustang ll suspension geometry(passive) are designedWilwood spindles
cells ... an inhibitor of Eg5causesmonopolar spindles
for use on a mounted surface or on a robotic platform(passive) are designedFixtured spindles
One other pathway of disregulation ... the abnormal centrosome amplificationcreatesmultipolar spindles
To test microtubule re - growth in the presence of gatastatin ( Figure 5—figure supplement 1B ) , all cells were treated with 10 μM STLC for 6 hrto createmonopolar spindles
palatalisesleadingreversibly spindles
Ectopic MAP4causesmonoastral spindles
with hard materials(passive) are designedEnviroGear spindles
treated with the Eg5 inhibitor STLCto createmonopolar spindles
32 mmpaintedwarkworth spindles
for use with hobbing , the cutting of gear tooth profiles(passive) are designedHobbing Spindles
A cell expressing a chromatin - targeted , FRET - based ( for fluorescence resonance energy transfer ) phosphorylation sensor for Aurora B was treated with a kinesin-5 inhibitorto createmonopolar spindles
hyperstable MTs(passive) caused bymultipolar spindles
that is involved in the centrosomal clusteringto preventmultipolar spindles
Aki1 depletion(passive) caused bymultipolar spindles
chemical inhibition of the Kinesin-5 motor(passive) created bymonopolar spindles
Tubulysin D , one of the most potent member of the tubulysins family ... ableto causemultipolar spindles
maintaining the coalescing mechanismto preventmultipolar spindles
Paclitaxelcausesmultipolar spindles
Klp61F depletion(passive) typically caused bymonopolar spindles
centriole splitting(passive) caused bymultipolar spindles
For example , how much time does your staff spendcreatingpleadings spindles
in multinucleated cells ( 28often resultin multinucleated cells ( 28
in death - inducing aneuploidyresultingin death - inducing aneuploidy
chromosome mis - segregation and genomic instabilitycausechromosome mis - segregation and genomic instability
to aneuploidy and impaired embryonic development ( Zhang et al . , 2004leadingto aneuploidy and impaired embryonic development ( Zhang et al . , 2004
from Eg5 siRNAresultingfrom Eg5 siRNA
from Eg5 inhibition in cells overexpressing GFP - CLASP2 wild - typeresultingfrom Eg5 inhibition in cells overexpressing GFP - CLASP2 wild - type
to altered division planes ( Fig EV2F and Videos EV3 and EV4).Takenleadingto altered division planes ( Fig EV2F and Videos EV3 and EV4).Taken
in unequal distribution of the chromosomes to the daughter cellsresultin unequal distribution of the chromosomes to the daughter cells
interest and good looks in our Karlstad Series of chairs that also highlight handcrafted carefulness with stretcher - based legscreatinginterest and good looks in our Karlstad Series of chairs that also highlight handcrafted carefulness with stretcher - based legs
to mitotic cell deathleadto mitotic cell death
of both centrosomal and acentrosomal spindle poles independent of centrosome numbercomposingof both centrosomal and acentrosomal spindle poles independent of centrosome number
of acentrosomal poles in mitosiscomposingof acentrosomal poles in mitosis
when a counter rotating toothing is incorporated into a normally toothed spindleresultwhen a counter rotating toothing is incorporated into a normally toothed spindle
from expression of E - caddCR4hresultingfrom expression of E - caddCR4h
when its activity is inhibitedresultwhen its activity is inhibited
from a single centrosome or two unseparated centrosomesoriginatingfrom a single centrosome or two unseparated centrosomes
from ILK or TACC3 depletion contain centriolesresultingfrom ILK or TACC3 depletion contain centrioles
from a failure of centrosome separation and an unusual microtubule assembly pathway via centriolar tripletsmight resultfrom a failure of centrosome separation and an unusual microtubule assembly pathway via centriolar triplets
cell death ... 10causecell death ... 10
from overexpression of GFP - CLASP2 S1234A upon immunostaining for different MT markersresultingfrom overexpression of GFP - CLASP2 S1234A upon immunostaining for different MT markers
from deregulated RHAMM expressionresultingfrom deregulated RHAMM expression
The circular mitotic figures ( CMF 's(passive) are caused byThe circular mitotic figures ( CMF 's
where it was suggested(passive) are caused bywhere it was suggested
to delayed mitotic exitleadto delayed mitotic exit
in abnormal chromosome segregation during mitosisresultin abnormal chromosome segregation during mitosis
aneuploidy and ultimately cell deathcauseaneuploidy and ultimately cell death
of attenuated and disorganized microtubules ( Fig . 5 H and Icomposedof attenuated and disorganized microtubules ( Fig . 5 H and I
to aberrant chromosomal distributionleadingto aberrant chromosomal distribution
from disruption of Lis1 functionresultingfrom disruption of Lis1 function
to chromosome missegregation and aneuploidyleadto chromosome missegregation and aneuploidy
in severe aneuploidyresultin severe aneuploidy
a delay in anaphase onset ( O'Connell and Wang , 2000causeda delay in anaphase onset ( O'Connell and Wang , 2000
cells from achieving a bipolar metaphase ( Fig .preventedcells from achieving a bipolar metaphase ( Fig .
to aneuploidy and cell death in a non - neuronal cell context9leadingto aneuploidy and cell death in a non - neuronal cell context9
from 4.1R downregulationresultingfrom 4.1R downregulation
to unequal segregation of genetic materialcould leadto unequal segregation of genetic material
8 minset8 min
errors in centrosome duplication or segregation to daughter cells which can lead to genomic imbalances [ 25 , 26causingerrors in centrosome duplication or segregation to daughter cells which can lead to genomic imbalances [ 25 , 26
to the onion - dome profile pegheadleadingto the onion - dome profile peghead
to aberrant cell divisionledto aberrant cell division