The disorder results from a mutation in the AKT1 gene ( which regulates cell growth ) ,causingmosaicism
when a mutation arises early in development(passive) is causedMosaicism
when nondisjunction occurs during mitotic division in the zygote after the fertilization(passive) is causedMosaicism
a mutation in TSC1 or TSC2 in a NC cell during embryonic development(passive) caused bymosaicism
Moreover mechanisms including meiotic non - disjunction and anaphase lag are reportedto causemosaicism
a genetic mutation of the NF1 gene that arises after conception and during early embryonic development(passive) is caused byMosaicism
postzygotic mitotic nondisjunction in somatic tissue rather than the meiotic nondisjunction seen binary options(passive) is caused byMosaicism
postzygotic mitotic nondisjunction in somatic tissue rather than the meiotic nondisjunction seen in the germ cell line that results in aneuploidy(passive) is caused byMosaicism
an error in mitosis(passive) may be caused byMosaicism
shock metamorphism(passive) was caused byMosaicism
shock crushing(passive) caused bymosaicism
Ring chromosomes are often unstable during mitosis ; as a result , it is common to find a ring chromosome in very minimal portion of cellsresultingmosaicism
LOH of variable chromosome(passive) caused bymosaicism
Mutational events occurring during embryonic developmentcan causemosaicism
a somatic recombination event in a monozygotic twin(passive) caused bymosaicism
Additionally , editing may happen after first embryonic division , due to persistence of Cas9 : gRNA complexesalso causingmosaicism
Mutations occurring early in developmentcan causemosaicism
OHSU scientistspreventedmosaicism
any one of numerous factors from paternal , maternal , or exogenous factors such as culture media or ovarian hyperstimulation(passive) can be caused byMosaicism
when cells with the normal amount of chromosomes and cells with an added chromosome mix and replicate a chromosome 21 in the latter.[3 ] Women who give birth to a child with Down syndrome have a higher chance of having another Down syndrome child(passive) is causedMosaicism
shownto consistently preventmosaicism
that only some copies of targeted genes are modifiedcausingmosaicism
that the second hit occurred early in embryogenesiscausingmosaicism
DNA mutations , epigenetic alterations of DNA , chromosomal abnormalities and the spontaneous reversion of inherited mutations(passive) can be caused byMosaicism
this change in tactic actually workedto preventmosaicism
X - chromosome inactivation in femalescausesmosaicism
no more than 1 h ... the first DNA replicationto preventmosaicism
from a mutation during development which is propagated to only a subset of the adult cellsmay resultfrom a mutation during development which is propagated to only a subset of the adult cells
from a mutation during development which is propagated to only a subset of the adult cellmay resultfrom a mutation during development which is propagated to only a subset of the adult cell
from random X inactivation ( MGI Ref ID J:41605)cellular phenotypeabnormal megakaryocyteresultingfrom random X inactivation ( MGI Ref ID J:41605)cellular phenotypeabnormal megakaryocyte
from random X inactivation ( MGI Ref ID J:41605 ) excess of abnormal megakaryocytes in the yolk sac and early fetal liver ( MGI Ref ID J:41605resultingfrom random X inactivation ( MGI Ref ID J:41605 ) excess of abnormal megakaryocytes in the yolk sac and early fetal liver ( MGI Ref ID J:41605
from a phenomenon known as X - inactivationalso resultsfrom a phenomenon known as X - inactivation
to just a segment of the coat being that patchy merle patternleadingto just a segment of the coat being that patchy merle pattern
in some cases in absence of transmission of the mutation to the offspringresultedin some cases in absence of transmission of the mutation to the offspring
major phenotypic changes and reveal the expression of lethal genetic mutations [ 15can causemajor phenotypic changes and reveal the expression of lethal genetic mutations [ 15
from a postzygotic mutation of FGFR3resultingfrom a postzygotic mutation of FGFR3
from postzygotic somatic cell mutationresultingfrom postzygotic somatic cell mutation
from multiple phage recombination eventsresultingfrom multiple phage recombination events
Around 1 percent of all Down syndrome cases(passive) are caused byAround 1 percent of all Down syndrome cases
less than 2.7 % of Down syndrome casescausesless than 2.7 % of Down syndrome cases
Almost all cases of Pallister - Killian mosaic syndrome(passive) are caused byAlmost all cases of Pallister - Killian mosaic syndrome
to organisms with some tissues or organs that bear the targeted mutation and some that do notwould leadto organisms with some tissues or organs that bear the targeted mutation and some that do not
when a de novo mutation arises after an embryo is formedcan resultwhen a de novo mutation arises after an embryo is formed
from somatic mutation in early embryonic cells.43,44resultingfrom somatic mutation in early embryonic cells.43,44
genetic mutation for Progeria in a small percentage of mother ’s cellscausinggenetic mutation for Progeria in a small percentage of mother ’s cells
from a mutation that occurs during postzygotic development and is propagated to only a subset of the adult cellsmay resultfrom a mutation that occurs during postzygotic development and is propagated to only a subset of the adult cells
from a mutation in one cell during development in which the mutation is passed on to only its daughter cellscan also resultfrom a mutation in one cell during development in which the mutation is passed on to only its daughter cells
from a mutation in one cell during development in which the mutation is passed on to only Mosaicism 's daughter cellscan also resultfrom a mutation in one cell during development in which the mutation is passed on to only Mosaicism 's daughter cells
skewed inactivation of mutated X chromosome ... protecting male child from deleterious effects of this mutationcausingskewed inactivation of mutated X chromosome ... protecting male child from deleterious effects of this mutation
from meiotic recombination of a paternal inversion followed by mitotic recombination during the first embryonic divisionsresultingfrom meiotic recombination of a paternal inversion followed by mitotic recombination during the first embryonic divisions
from a known mosaic embryo transferresultingfrom a known mosaic embryo transfer
oftenresultsoften
Differing eye color in a person(passive) is caused byDiffering eye color in a person
a person to have two different colored eyescan causea person to have two different colored eyes
in traits expressed in seemingly random patterns ( e.g. , skin mosaicismoften resultsin traits expressed in seemingly random patterns ( e.g. , skin mosaicism
from de novo somatic eventsresultingfrom de novo somatic events
differences among a person 's cellscan createdifferences among a person 's cells
from mutations occurring at different times and sites in developmentresultingfrom mutations occurring at different times and sites in development
varying expressivity of inherited diseases , aggregation of disorders regarded as " new mutations " in ostensibly healthy families , and neoplasiamay causevarying expressivity of inherited diseases , aggregation of disorders regarded as " new mutations " in ostensibly healthy families , and neoplasia
to 2 cell lineages , which results in areas of hypopigmented ( light areas of skint ) and hyperpigmented skin ( darker areas of skinoften leadsto 2 cell lineages , which results in areas of hypopigmented ( light areas of skint ) and hyperpigmented skin ( darker areas of skin
The development of the segmental component in a generalized disease(passive) is caused byThe development of the segmental component in a generalized disease
Muckle - Wells syndrome in a collaborative study with the Spanish groupcausesMuckle - Wells syndrome in a collaborative study with the Spanish group
in tetraploidizationoriginatingin tetraploidization
from inactivation of an X - chromosome in femalesresultingfrom inactivation of an X - chromosome in females
Four clinical patterns ,(passive) caused byFour clinical patterns ,
from the use of this technologyresultingfrom the use of this technology