to silencing of the spindle checkpointleadingto silencing of the spindle checkpoint
to mitotic arrestleadingto mitotic arrest
mitotic arrest and accumulation of cells in G2 / Mcausingmitotic arrest and accumulation of cells in G2 / M
in chromosome segregation defects and aneuploidyresultsin chromosome segregation defects and aneuploidy
mitotic arrest of the cellcausesmitotic arrest of the cell
to aneuploidy and chromosome damageleadingto aneuploidy and chromosome damage
to mitotic arrestleadingto mitotic arrest
to apoptosis mediated via dephosphorylation of Bcl-2 which allows pro - apoptotic proteinthen leadsto apoptosis mediated via dephosphorylation of Bcl-2 which allows pro - apoptotic protein
chromosomal missegregation and aneuploidycauseschromosomal missegregation and aneuploidy
metaphase arrestcausingmetaphase arrest
to metaphase arrestleadsto metaphase arrest
The separation of the chromosomes(passive) is caused byThe separation of the chromosomes
to cell cycle arrest and cell deathleadsto cell cycle arrest and cell death
in cell cycle arrest at the G2 / M phase and apoptosismay resultin cell cycle arrest at the G2 / M phase and apoptosis
to cell cycle growth arrestleadsto cell cycle growth arrest
to increased microtubuleleadingto increased microtubule