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Dr. Giguère have been hypothesizedto causea mitochondrial proton leak
as well asin other tissues , and has been shownto contributeto mitochondrial proton leakage
a change in inner membrane surface area ... by whichmay influenceproton leak
the drugs or their combination(passive) caused byproton leak
our analysis using mitochondrial calcium inhibitor and Seahorse XF96 mitochondrial function analyzer ... increasing mitochondrial calcium entryresultedin mitochondrial proton leakage
the abundance of UCP-2 , a proteincausesmitochondrial proton leakage ( 30–32
the factorscontributingto mitochondrial proton leak
This mechanismpreventsproton leak
proton uncoupling in the mitochondrial inner membrane in brown fat and beige fat(passive) caused byproton leak
Drp1 KD at high glucose ( Fig . 2F(passive) is provoked byan increase in mitochondrial proton leak
This result ... in whichcausean increase in mitochondrial proton leak
UCP-3 ) expressionresultingin mitochondrial proton leak
hypoxia +(passive) caused byproton leak
protein 1 ( UCP1causesmitochondrial proton leak
to less reactive oxygen species ( ROS ) productionleadsto less reactive oxygen species ( ROS ) production
to diminished MMP , which in turn is an early event in the apoptotic processleadsto diminished MMP , which in turn is an early event in the apoptotic process
to reduction in the efficiency of ATP production from oxidative phosphorylationleadingto reduction in the efficiency of ATP production from oxidative phosphorylation
ETCmay ... contributeETC
to heat production for endothermy in this species ... if the measured state 4 respiration rates and membrane potentials reflect the conditions under which the mitochondria operate in vivocontributesto heat production for endothermy in this species ... if the measured state 4 respiration rates and membrane potentials reflect the conditions under which the mitochondria operate in vivo
to impaired ATP production ( 35leadsto impaired ATP production ( 35
to membrane depolarization ( mild uncouplingleadingto membrane depolarization ( mild uncoupling
to higher Δψ and consequently increased O2− productionleadto higher Δψ and consequently increased O2− production
to reduction of ATP production [ 31leadingto reduction of ATP production [ 31
in released energy With the majority of our clients sharing weight loss goalsresultingin released energy With the majority of our clients sharing weight loss goals
directly to the induction of apoptosis ( 47 , 48can contributedirectly to the induction of apoptosis ( 47 , 48
uncoupling between respiration and OXPHOS.Mitochondrial uncoupling may occur through a variety of mechanisms including altered lipid peroxidationcausinguncoupling between respiration and OXPHOS.Mitochondrial uncoupling may occur through a variety of mechanisms including altered lipid peroxidation
an increase in mitochondrial energetic efficiency and an increase in ROS contentcausedan increase in mitochondrial energetic efficiency and an increase in ROS content
to ∼25 % of the resting oxygen consumption of mammalscontributesto ∼25 % of the resting oxygen consumption of mammals
from interactions of resveratrol with the mitochondrial electron transport chainresultingfrom interactions of resveratrol with the mitochondrial electron transport chain
to the postanoxic oxygen debt in oystersmay ... contributeto the postanoxic oxygen debt in oysters
in an increase of mitochondrial couplingresultingin an increase of mitochondrial coupling
to energy dissipation ( 3leadingto energy dissipation ( 3
individual differences in performance at elevating temperatures ... but this remains to be exploredcould influenceindividual differences in performance at elevating temperatures ... but this remains to be explored
to approximately 25 % of the resting respiratory rate [ 24contributesto approximately 25 % of the resting respiratory rate [ 24
to a partial compensation of the increase in V̇o2 caused by an elevated energy demandleadsto a partial compensation of the increase in V̇o2 caused by an elevated energy demand
significantly to BMRcontributessignificantly to BMR