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Qaagi - Book of Why

Causes

Effects

generation itselfcausesproton leak via lipid peroxidation / membrane damage

a particle acceleratordesigned primarilyto study proton - proton collision

the decrease in membrane potential(passive) caused bythe down - regulation of inner membrane proton leak

by increased permeability of their inner membrane(passive) caused bythe proton leakage process of mitochondria

increased permeability of their inner membrane(passive) caused bythe proton leakage process of mitochondria

where ischemia has been shownto causean increase in proton leak [ 33

A. Long alkyl chain TPP+ derivativescausean increase in proton leak - driven respiration

the Timestrikerscausingmassive energy leaks

Further ( rather complicated ) experiments ... a proteincausesefficiency - sapping proton leakage across the mitochondrial membrane

where ischemia has been shownto causean increase in proton leak

Leak testing equipmentis designedto detect hydrogen leaks

Silver binds to surface membranes and proteinscausingproton leaks in the membrane

any mechanismresultingin proton leak ( i.e. uncoupling

protein 1 ( UCP1causesmitochondrial proton leak

They have been hypothesizedto causea mitochondrial proton leak

Although UCP1 is knownto influencemitochondrial proton leak

3 connected holes(passive) composed byproton 's quark+

By contrast , the ability of the high - safflower oil diet to produce a less pronounced increase in the efficiency of catch - up fat may partly reside in increased incorporation of arachidonic acid in hepatic mitochondrial membranesleadingto enhanced proton leak and mitochondrial uncoupling

membranescausingproton leakage and depolarization

This processcauseshydrogen leaks

chronic overexpression of cPLA2 in the MIN6 cellscausedupregulation of the mitochondrial proton transporter UCP-2

This methodcauseshydrogen leaks

Mitochondria ... ROS ) generationresultedfrom the ? electron leak

This protein causes an increase in the permeability of the inner mitochondrial membranescausingproton leak

by the drugs or their combination(passive) caused byproton leak

generation itselfcausesproton leak

One factorcontributesto this proton leak

when water was discovered coming out of an electrical junction box at the facility(passive) was accidentally discoveredThe tritium leak

membrane integrityleadingto proton leakage

energy restrictionwould influenceproton leakage

fatty acidsleadingto proton leakage

specific membrane proteins - uncouplers ( uncoupler proteins - UCPs(passive) is caused byProton leakage

activation of Hv1 proton channels using patch - clamp fluorometry recordings from channels labeled with the Venus fluorescent protein at intracellular domains(passive) caused bythe proton depletion

to energy dissipation and heat productionleadingto energy dissipation and heat production

to energy dissipationleadingto energy dissipation

non - phosphorylating respiration(passive) caused bynon - phosphorylating respiration

uncoupling of the respiratory chain electron transportcausesuncoupling of the respiratory chain electron transport

to lower islet ROScould leadto lower islet ROS

to the generation of heat instead of the production of ATPleadingto the generation of heat instead of the production of ATP

to energy homeostasiscontributeto energy homeostasis

decreased maximum respiratory capacity.[34causesdecreased maximum respiratory capacity.[34

less superoxide generationDoes ... causeless superoxide generation

explosionscould causeexplosions

to the uncoupling of the electron respiratory chain and the collapse of membrane potential , which in turn leads to a cessation of ATP generation in mitochondrialeadto the uncoupling of the electron respiratory chain and the collapse of membrane potential , which in turn leads to a cessation of ATP generation in mitochondria

in an increase of mitochondrial couplingresultingin an increase of mitochondrial coupling

to impaired ATP production ( 35leadsto impaired ATP production ( 35

electric current to flow through a wire from an anode to a cathodecauseselectric current to flow through a wire from an anode to a cathode

to increased free radical generationleadingto increased free radical generation

to health problemscan also leadto health problems

oxidative stress that can lead to cell deathcausesoxidative stress that can lead to cell death

to more water in the atmosphere , which could accelerate global warmingcould leadto more water in the atmosphere , which could accelerate global warming

to cell deathcan leadto cell death

to cell death ( apoptosiscan leadto cell death ( apoptosis

to reduction in the efficiency of ATP production from oxidative phosphorylationleadingto reduction in the efficiency of ATP production from oxidative phosphorylation

decreased maximum respiratorycausesdecreased maximum respiratory

in the production of fewer ROSmay resultin the production of fewer ROS

in the production of fewer ROS in the first placemay resultin the production of fewer ROS in the first place

significantlycontributessignificantly

energy depletioncausingenergy depletion

to neutrinos ( or some other invisible particle ) being producedledto neutrinos ( or some other invisible particle ) being produced

to creation of stable excitation of physical vacuumleadsto creation of stable excitation of physical vacuum

to energy productionleadsto energy production

to the dissipation of energy as heatleadingto the dissipation of energy as heat

to membrane depolarization ( mild uncouplingleadingto membrane depolarization ( mild uncoupling

in an enhancement of kcatresultingin an enhancement of kcat

to a rapid consumption of energy without generation of ATPleadsto a rapid consumption of energy without generation of ATP

the neutronHow was ... discoveredthe neutron

to the Academyare contributingto the Academy

the Electricity stageinfluencesthe Electricity stage

the Strength levelinfluencesthe Strength level

to more cytosolicleadsto more cytosolic

to more cytosolic Na+leadsto more cytosolic Na+

The Best 15 , 20 , 25 , 30 , 35 and 70 MeV(passive) are designedThe Best 15 , 20 , 25 , 30 , 35 and 70 MeV

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