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Qaagi - Book of Why

Causes

Effects

DHA and EPAcausedincreased membrane fluidity

ATP - sensitive potassium channelscausingmembrane depolarization

inhibit ATP - sensitive potassium channelscausingmembrane depolarization

ATP inhibit ATP - sensitive potassium channelscausingmembrane depolarization

allows entry of cations , including calcium ( Ca2 + ) , into the cellto causemembrane depolarization

which then promote closure of ATP - sensitive K+ ( KATP ) channelscausingmembrane depolarization

Inhibition of K+ channelscausesmembrane depolarization

by inhibition of potassium channels that otherwise maintain the resting potential(passive) is caused bymembrane depolarization

by inhibition of potassium channels that otherwise maintain the resting potential(passive) is causedmembrane depolarization

inhibition of potassium channels that otherwise maintain the resting potential(passive) is caused bymembrane depolarization

potassium channelscausingmembrane depolarization

Extracellular potassium accumulation is known ... , and has been associated with conduction block in central nervous system neuronsto causemembrane depolarization

High K+ stimulationprovokesmembrane depolarization

the inhibition of K(+ ) channel by NAcausedmembrane depolarization

that increases in intraluminal pressure leads to the activation of cation channels in smooth muscle cellsto causemembrane depolarization

by inhibition of potassium channels that otherwise maintain the resting potential.[4(passive) is caused bymembrane depolarization

by inhibition of potassium channels that otherwise maintain the resting potential.[4(passive) is causedmembrane depolarization

by inhibition of potassium channels that otherwise maintain the resting(passive) is caused bymembrane depolarization

by inhibition of potassium channels that otherwise maintain the resting(passive) is causedmembrane depolarization

The rapid movement into the cellcausesmembrane " depolarization

by increased content in unsaturated fatty acids(passive) caused bycellular membrane fluidity

activation of GABAA receptorscausesmembrane depolarization

by elevated extracellular K+(passive) caused bymembrane depolarization

Reduced KATP channel activity is in turn expectedto causemembrane depolarization

anion ) channels on the plasma membranecausingmembrane depolarization

potassium leak inhibitioncausingmembrane depolarization

channelscausesmembrane depolarization

channelscausemembrane depolarization

that binds to receptorscausemembrane depolarization

channelto causemembrane depolarization

by an excitatory stimulus activates Na+ pumps(passive) caused byMembrane depolarization

the rapid and transient stimulation of alpha - MSH release induced by GABA ... a chloride conductancecausesmembrane depolarization

influxcausesmembrane depolarization

Glutamate exposurecausesmembrane depolarization

ATPcausesmembrane depolarization

a transient - inward currentcausesmembrane depolarization

by an excitatory stimulus activates(passive) caused byMembrane depolarization

An Overview Since potassium channel closuremay causemembrane depolarization

The influx of cations through TRPV1causesmembrane depolarization

stretch - activated currents ... sufficientto causemembrane depolarization

to increased permeability of the membraneleadsto increased permeability of the membrane

in enhanced passive diffusion of the drugs ( 30resultingin enhanced passive diffusion of the drugs ( 30

alsoresultsalso

greater uptake of auranofin(passive) could be influenced bygreater uptake of auranofin

to the opening of voltage - dependent calcium channels and subsequent calcium entryleadingto the opening of voltage - dependent calcium channels and subsequent calcium entry

to plasma membrane blebbing and sheddingleadingto plasma membrane blebbing and shedding

to opening of voltage dependent calcium channelsleadingto opening of voltage dependent calcium channels

voltage - gated Ca2 + channels to opencausesvoltage - gated Ca2 + channels to open

to the opening of voltage - gated Ca2 + channels in the plasma membraneleadsto the opening of voltage - gated Ca2 + channels in the plasma membrane

Ca2 + entry through voltage - operated Ca2 + channels , activation of Ca2causingCa2 + entry through voltage - operated Ca2 + channels , activation of Ca2

opening of voltage dependent Ca2 +causesopening of voltage dependent Ca2 +

opening of voltage dependent Ca2causesopening of voltage dependent Ca2

to the generation of Ca2 + spike potentials and an increase in intracellular Ca2ledto the generation of Ca2 + spike potentials and an increase in intracellular Ca2

to calcium influx through L - type calcium channelsleadingto calcium influx through L - type calcium channels

to the opening of Ca2 + channelsleadingto the opening of Ca2 + channels

of a lipid bilayer of phospholipids with the hydrophobic edge screened by two amphipathic proteinscomposedof a lipid bilayer of phospholipids with the hydrophobic edge screened by two amphipathic proteins

to an influx of calciumleadingto an influx of calcium

Increase in potassium ion in extracellular(passive) is causedIncrease in potassium ion in extracellular

to cell contractionleadsto cell contraction

to Ca influx through L - type Ca channelsleadingto Ca influx through L - type Ca channels

release of the excitatory neurotransmitter glutamatecausesrelease of the excitatory neurotransmitter glutamate

to the delivery of active enzymes at the cell surfaceleadingto the delivery of active enzymes at the cell surface

in extracellular calcium entryresultingin extracellular calcium entry

to cell death by directly inhibiting potassium channelsleadsto cell death by directly inhibiting potassium channels

to firing of action potentialsleadingto firing of action potentials

to increased firingleadto increased firing

to calciumleadingto calcium

Ca2 + entrycausingCa2 + entry

to Ca2 +leadingto Ca2 +

to Ca2leadingto Ca2

in increasedresultingin increased

to the action potentialleadingto the action potential

to increased blockingleadsto increased blocking

to increased blockingleadsto increased blocking

in turnleadsin turn

a nerve impulse or action potential if a certain threshold is reached within the neuroncan causea nerve impulse or action potential if a certain threshold is reached within the neuron

an opening of the gates that previously had an inhibitory effect on the neuron they were gatingwill causean opening of the gates that previously had an inhibitory effect on the neuron they were gating

to excitationDoes ... always leadto excitation

to 7leadingto 7

Excitatory responses(passive) are caused byExcitatory responses

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