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Qaagi - Book of Why

Causes

Effects

Barium sulfate within alveolar spacescausesalveolar shunting as well as ventilation / perfusion distribution abnormalities

Scoliosis ... tendsto causea restrictive ventilatory defect , along with ventilation - perfusion mismatch and hypoxemia

blood ... in turncontributesto serious ventilation / perfusion mismatch and hypoxemia

The inflammationcausesventilation - perfusion mismatch and results in hypoxemia

Scoliosiscausesrestrictive ventilatory defect with ventilation - perfusion mismatch and hypoxemia

In this unusual patient , mild muscular weakness , caused by diabetes , and central alveolar hypoventilation have acted in synergismto causeabnormal ventilation and right ventricular failure

one lung ventilationcausesventilation perfusion ( V / Q ) mismatch

Hypotensive anesthetic techniquesmay also causeabnormalities of the pulmonary ventilation / perfusion ratio

Hypotensive anesthetic techniquesmay also causeabnormalities of pulmonary ventilation perfusion ratio

Concerns of one lung ventilationcausesventilation perfusion ( V / Q ) mismatch

A pulmonary emboluswill typically causeperfusion defects with normal ventilation

The ventilation is therefore affectedleadingto a ventilation perfusion mismatch and hypoxia

In patients with inflammation like sepsis or ARDS , HPV is impairedresultingin a ventilation - perfusion mismatch and hypoxia

Most importantly , the respiratory system undergoes alterations in ventilation and pulmonary perfusionresultingin ventilation and perfusion ( V / Q ) mismatch

neural crestcausescraniofacial and cardiac defects

decreased ventilation in the lungcausesventilation / perfusion mismatching and hypoxia

fairly severe constriction of small airways ( less than 2 mm in diameter(passive) must be caused byventilation defects observed in asthmatics

overperfusion relative to ventilationleadingto ventilation - perfusion mismatch and hypoxemia

The dilation of these blood vessels causes overperfusion relative to ventilationleadingto ventilation - perfusion mismatch and hypoxemia

+ The dilation of these blood vessels causes overperfusion relative to ventilationleadingto ventilation - perfusion mismatch and hypoxemia

soft tissuecausesapparent perfusion defects

Vasodilation increases the pulmonary blood flow and cardiac outputsubsequently leadingto perfusion ventilation mismatch and arteriovenous shunts

This disparity in timing of myocardial contraction may become exaggerated with increased pacing rate during exercisecausingscintigraphic perfusion defects

conditionscausingventilation - perfusion defect

fluid ... the alveolileadsto ventilation and perfusion difficulties

to pull fluid from the pulmonary capillary bed and into the alveolileadingto ventilation and perfusion difficulties

enough negative intrathoracic pressure to pull fluid from the pulmonary capillary bed and into the alveolileadingto ventilation and perfusion difficulties

the wallscausesventilation - perfusion abnormalities

blockagescausingperfusion defects

by aspiration of water(passive) caused byventilation perfusion abnormalities

the coronary anatomy ... better pinpointare causingperfusion defects

PE ( 12 , 17 - 19(passive) caused byperfusion defects

atelectasis , cardiac motion and streak artefactcan ... causeperfusion defects

the left pulmonary collapse(passive) caused byventilation - perfusion mismatch

reduced respiratory reservecausingventilation / perfusion mismatch

This type of respiratory failureresultsfrom a mismatch between ventilation and perfusion

Primary pulmonary hypertensioncausesventilation - perfusion mismatch

Pneumoniacausesventilation - perfusion mismatch

respiratory failureresultsfrom a mismatch between ventilation and perfusion

Damage to surfactant from both fresh and saltwatercan leadto ventilation and perfusion missmatching

to hypoxiafurther leadingto hypoxia

to hypoxemiamay leadto hypoxemia

to hypoxemialeadsto hypoxemia

in increased arterial oxygen tensionresultedin increased arterial oxygen tension

althoughmay ... contributealthough

to hypoxemia , pneumonia , and postoperative pulmonary complicationsleadingto hypoxemia , pneumonia , and postoperative pulmonary complications

diseases(passive) caused bydiseases

diseases(passive) caused bydiseases

in hypoxiacan resultin hypoxia

to hypoxaemialeadingto hypoxaemia

to hypoxemialeadingto hypoxemia

to hypoxiacan leadto hypoxia

asthma control and symptomsmay influenceasthma control and symptoms

to reduced arterial oxygen concentrationleadingto reduced arterial oxygen concentration

to reduced arterial oxygen concentrationleadsto reduced arterial oxygen concentration

in increased Pco2resultin increased Pco2

hypoxia(passive) caused byhypoxia

in hypoxiaresultin hypoxia

hypoxemia with normalcausehypoxemia with normal

hypoxemia(passive) caused byhypoxemia

in hypoxemiacan resultin hypoxemia

to inconsistent drug uptakecan leadto inconsistent drug uptake

in hypoxemia [ 5can resultin hypoxemia [ 5

in hypoxemia and hypercapniaresultingin hypoxemia and hypercapnia

in hypoxiacan resultin hypoxia

to hypoxemia , pneumonia , and postoperative pulmonary complicationsleadingto hypoxemia , pneumonia , and postoperative pulmonary complications

Arterial hypoxemia(passive) is caused byArterial hypoxemia

in arterial hypoxemialeadsin arterial hypoxemia

significantly to her deathcontributedsignificantly to her death

to hypoxemialeadingto hypoxemia

to hypoxemialeadsto hypoxemia

Hypoxemia(passive) caused byHypoxemia

hypoxia , hypercapnia , and acidosiscauseshypoxia , hypercapnia , and acidosis

to decrease in oxygenationleadsto decrease in oxygenation

usuallyresultsusually

to hypoxemia , thromboembolic diseaseleadingto hypoxemia , thromboembolic disease

to impairment of gas exchange and subsequent hypoxemialeadingto impairment of gas exchange and subsequent hypoxemia

to hypoxaemialeadsto hypoxaemia

to hypoxia , hypercapnia and need of mechanical ventilationleadsto hypoxia , hypercapnia and need of mechanical ventilation

in activation of the liverresultingin activation of the liver

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