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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

the presence of too many mast cells in the body(passive) is caused bymast cell disease

Siglec-8 ligationdoes ... causemast cell apoptosis , mast cell apoptosisinhibits

But I do not believecausesmast cell disease

Siglec-8 ligationdoes ... causemast cell apoptosis

a mutation in ADGRE2(passive) caused byaberrant mast cell degranulation

mast cellscausingdegranulation of the mast cells

mast cellscausingdegranulation of mast cells

an allergen , the cell membrane of the mast cell rupturescausesdegranulation of the mast cells

Binding of antigen to the bound IgEcausesmast cell degranulation

Their activation through the cross - linking of bound IgEprovokesmast cell degranulation

the food antigencauseddegranulation of mast cells

by an antigen(passive) caused bydegranulation of mast cells

the same antigenwill causedegranulation of mast cells

Antibodies to IgE cross - linking cell bound IgEcould causemast cell degranulation

cellscausingdegranulation of mast cells

substancescausingdegranulation of mast cells

the medications and substancescausingdegranulation of mast cells

the production of IgE antibodieswould ... causemast cell degranulation

Ultrasoundcan causedegranulation of mast cells

the absorption of whichcausesperifollicular mast cell degranulation

Cross - linking of IgEcausesmast cell degranulation

Allergen exposure thenresultsin mast cell degranulation

IgE in cells can last for weeksresultingin mast cell degranulation

allergic reactioncausingdegranulation of mast cells

Complement activationcan causemast cell degranulation

mast cellsresultsin mast cell degranulation

then to mast cellscausingmast cell degranulation

Peptidescan causedegranulation of mast cells

Factors other than IgEcan causemast cell degranulation

Allergen unmasking thenresultsin mast cell degranulation

Symptoms(passive) can be causedDegranulation of mast cells

Pcausingdegranulation of mast cells

The activation of this cascadecausesmast cell degranulation

Allergen experience thenresultsin mast cell degranulation

various nonspecific triggersmay causeperioperative mast cell degranulation

SCF / c - Kit interaction in mast cellsresultsin mast cell degranulation

Lack of BH4may resultin mast cell degranulation

by compound 48/80(passive) provoked bymast cell degranulation

by compound 48/80(passive) caused bymast cell degranulation

compound 48/80(passive) provoked bymast cell degranulation

more inflammationcausemore inflammation

the release of a wide variety of chemical mediators such as histamine , leukotriene , and prostaglandins [ 1 , 2causesthe release of a wide variety of chemical mediators such as histamine , leukotriene , and prostaglandins [ 1 , 2

to the release of inflammatory mediatorsagain ... leadsto the release of inflammatory mediators

in reduced levels ofresultedin reduced levels of

to neurogenic inflammationcontributeto neurogenic inflammation

to the rapid release of various inflammatory mediators , such as histamine , leukotrienes and prostaglandins , which , in turn , cause vasodilation and leakage of plasma in and below the skinleadsto the rapid release of various inflammatory mediators , such as histamine , leukotrienes and prostaglandins , which , in turn , cause vasodilation and leakage of plasma in and below the skin

nociceptor activation in the dura as well as in the spinal cordcausingnociceptor activation in the dura as well as in the spinal cord

inflammationcausinginflammation

in the release of histamine causing bronchoconstrictioncan resultin the release of histamine causing bronchoconstriction

in release of mediators such as histamineresultsin release of mediators such as histamine

to anaphylaxisleadingto anaphylaxis

reactioncausingreaction

the massive histamine release(passive) caused bythe massive histamine release

a massive histamine releasecausesa massive histamine release

in the release of chemical mediatorsresultingin the release of chemical mediators

to histamine releaseleadsto histamine release

in a histamine releaseresultsin a histamine release

to the release of various mediators , such asleadsto the release of various mediators , such as

to histamine release and typical IgE hypersensitivity reaction fromleadsto histamine release and typical IgE hypersensitivity reaction from

to release of histamine and other mast cell mediatorsleadsto release of histamine and other mast cell mediators

This drop in blood pressure ( shock ) with accompanying contractions of bronchial smooth muscle(passive) is caused byThis drop in blood pressure ( shock ) with accompanying contractions of bronchial smooth muscle

to the rapid release of various inflammatory mediatorsleadsto the rapid release of various inflammatory mediators

to mast cell activation syndrome or mastocytosiscan leadto mast cell activation syndrome or mastocytosis

in increased vascular permeabilityresultsin increased vascular permeability

to various cytokine releaseleadsto various cytokine release

from the bone marroworiginatefrom the bone marrow

from bone marroworiginatefrom bone marrow

from the bone marrow andoriginatefrom the bone marrow and

to release of inflammatory mediators causing allergic reactionleadingto release of inflammatory mediators causing allergic reaction

multiple food intolerancescausesmultiple food intolerances

to the release of histamine and other mediators into the circulationleadingto the release of histamine and other mediators into the circulation

in the release of the pro - inflammatory cytokine TNF - a from the cellsresultsin the release of the pro - inflammatory cytokine TNF - a from the cells

to the release of histamine and other mediators such as tryptaseleadingto the release of histamine and other mediators such as tryptase

inflammationcausesinflammation

to inflammationleadingto inflammation

in release of histamineresultsin release of histamine

in the release of histamineresultsin the release of histamine

from the boneoriginatefrom the bone

the release of tryptasecausesthe release of tryptase

dermal edemacausesdermal edema

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Smart Reasoning:

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