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Smart Reasoning:

C&E

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Qaagi - Book of Why

Causes

Effects

by reactions to high histamine foods(passive) caused bymast cell activation disorder

reactions to high histamine foods(passive) caused bymast cell activation disorder

the immune disease irritating their mast cells so much(passive) caused bymast cell activation syndrome

Lyme diseasemay ... causemast cell activation syndrome

Lyme diseasecan causemast cell activation syndrome

Lyme diseasecan causeMast Cell Activation Syndrome

many thingscan setoff mast cell activation syndrome

Lyme disease(passive) can be caused byMast Cell Activation Disorder

exposure to the allergencausesmast cell activation and degranulation

triggerscausemast cell activation / degranulation

normally(passive) is ... setFcRI - mediated mast cell activation

the c - kit receptorcausesactivation of the mast cells

Exposure to allergenscausesactivation of mast cells

both allergic and non - allergic triggers(passive) can be caused byActivation of mast cells

Subsequent binding of this IgE by an antigen ( called an allergenresultsin mast cell activation

by adenosine receptor stimulation(passive) caused bymast cell activation

Stimulation of these receptorscan leadto mast cell activation

that allergy is notis causingactivation of those mast cells

able ... basophilsto causeactivation of mast cells

During the reperfusion phase , increased generation of ROS occursresultingin mast cell activation

some cases ... IgE - independent mechanismsleadto mast cell activation

Therefore , it is concludedcausedactivation of mast cells

a signaling cascadecausesmast cell activation

a signaling cascadeleadingto mast cell activation

triggers ... moleculescan causemast cell activation

many other stimuli and conditionscan causemast cell activation

H4 histamine receptor responseleadingto Mast Cell Activation

T - cellsresultsin mast cell activation

mast cells or act on other chemical signalsleadto mast cell activation

More histamine releasecan causemore mast cell activation

the mechanisms by whichleadto mast cell activation

the mechanismsleadingto mast cell activation

This bindingcausesactivation of the mast cell

eventsleadingto mast cell activation

the mechanismleadsto mast cell activation

Any activitycan causemast cell activation

no productionresultsin mast cell activation

no productionleadsto mast cell activation

Immunological urticaria ... T - cellsresultsin mast cell activation

by infection(passive) is caused bymast cell activation

her immune system to become hyper sensitivecausesher immune system to become hyper sensitive

severe organ inflammationis causingsevere organ inflammation

her immune system to be hyper sensitive and reactcausesher immune system to be hyper sensitive and react

temporary symptomscan causetemporary symptoms

temporary symptoms in multiple organ systemscan causetemporary symptoms in multiple organ systems

histamine intolerancecauseshistamine intolerance

the POTSis causingthe POTS

in pulmonary diseasecan resultin pulmonary disease

to neutrophil recruitment ... thus aggravating the local inflammatory responseleadsto neutrophil recruitment ... thus aggravating the local inflammatory response

Lyme DiseasecausesLyme Disease

to the synthesis and release of various cytokinesalso leadsto the synthesis and release of various cytokines

to dilation and increased permeability of blood vesselsleadsto dilation and increased permeability of blood vessels

to release of multiple mediators with potent vasodilatory , inflammatory and nociceptive properties through which they participate in acute and delayed hypersensitivity reactions in the skinleadsto release of multiple mediators with potent vasodilatory , inflammatory and nociceptive properties through which they participate in acute and delayed hypersensitivity reactions in the skin

to the release of mediators such as histamines , prostaglandins , leukotrienes and heparin that enhance vascular permeability to produce edemaleadsto the release of mediators such as histamines , prostaglandins , leukotrienes and heparin that enhance vascular permeability to produce edema

the secretion of histaminewill causethe secretion of histamine

to allergic inflammatory responseleadsto allergic inflammatory response

to release of preformed mediators and to generation of other potent biological substances that have both physiological and pathophysiological effectsleadsto release of preformed mediators and to generation of other potent biological substances that have both physiological and pathophysiological effects

to degranulationleadsto degranulation

what is called " immediate hypersensitivitydoes causewhat is called " immediate hypersensitivity

in exocytosis of preformed chemical mediatorsresultsin exocytosis of preformed chemical mediators

7leads7

release of inflammatory mediators , which take part in mediating nasal congestioncausesrelease of inflammatory mediators , which take part in mediating nasal congestion

in degranulation and secretion of a host of vasoactive amines , proteases , and proinflammatory cytokinesresultsin degranulation and secretion of a host of vasoactive amines , proteases , and proinflammatory cytokines

release of inflammatory mediators , which take part in mediating nasal congestion ( 4)[Acausesrelease of inflammatory mediators , which take part in mediating nasal congestion ( 4)[A

to development of a chemotactic gradient during systemic hypoxia and that this is a critical event in the subsequent development of microvascular inflammation ( 41contributesto development of a chemotactic gradient during systemic hypoxia and that this is a critical event in the subsequent development of microvascular inflammation ( 41

to changes in the topography of microtubulesleadsto changes in the topography of microtubules

them to release histamine and other chemicals , which causes localised redness , swelling , itching , and , sometimes , blisteringcausesthem to release histamine and other chemicals , which causes localised redness , swelling , itching , and , sometimes , blistering

massive Histamine release resulting in Anaphylaxiscausingmassive Histamine release resulting in Anaphylaxis

in the release of preformed mediators , such as histamine , and cytokinesresultsin the release of preformed mediators , such as histamine , and cytokines

degranulation and release of cytokinescausesdegranulation and release of cytokines

in release of many proinflammatory mediatorsresultingin release of many proinflammatory mediators

increased vascular permeability(passive) caused byincreased vascular permeability

widespread vasodilationcauseswidespread vasodilation

in histamine releaseresultingin histamine release

histamine releasecauseshistamine release

in the release of preformed mediators , such as histamineresultsin the release of preformed mediators , such as histamine

to release of soluble mediatorsleadingto release of soluble mediators

to mediator releaseleadingto mediator release

to degranulation and the production of several cytokines and chemokinesleadingto degranulation and the production of several cytokines and chemokines

to inflammation in sickle micecontributesto inflammation in sickle mice

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