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various reasons&comma(passive) caused byBone marrow fibrosis
Myelofibrosis ... a clonal stem cell neoplasmcausesfibrosis of the bone marrow
fibrogenic factorsleadingto marrow fibrosis
Many other disorderscan causebone marrow fibrosis
activation of marrow mesenchymal cells , which differentiate into fibroblast - like cells , which form fibrous tissue(passive) is caused byThe marrow fibrosis
the secretion of particular cytokines that stimulate the growth and proliferation of fibroblasts [ 8(passive) may be caused byMarrow fibrosis
the stromal cells of the bone marrow microenvironmentresultsin the marrow fibrosis
abnormal blood stem cells in the bone marrow(passive) may be caused bymarrow fibrosis
undifferentiated osteogenic cellsresultingin marrow fibrosis
an underlying inflammatory disease or another neoplastic disease(passive) caused bybone marrow fibrosis
The histologic distinction between PMF and “ myelofibrosis associated with nonmyeloid disorders ... clonal markers , other neoplasms or inflammatory diseasecan leadto marrow fibrosis
excess activation of this receptor ... excess megakaryocyte - mediated PDGF and TGF - beta productioncreatesbone marrow fibrosis
up - regulated Wnt / β - catenin signaling ... in turncausedmarrow fibrosis
Excess of Parathyroid Hormonecausingmarrow fibrosis
leukemic cells(passive) caused bymarrow fibrosis
Uncontrolled hy - per - parathyroidismcausesbone marrow fibrosis
anagrelide used in younger patients for long periods of timeare causingfibrosis of the bone marrow
TPTD treatment(passive) caused bythe bone marrow fibrosis
excess PDGFcausingmarrow fibrosis Get
rhTPO administrationcausedbone marrow fibrosis
hyperparathyroidism(passive) caused bymarrow fibrosis
other types of cancercan causefibrosis of the marrow
to dry tap on aspirationleadingto dry tap on aspiration
from primary hyperparathyroidism.[ncbi.nlm.nih.gov ] Osteosclerosis , hypertrophic osteoarthropathy and periostitisresultingfrom primary hyperparathyroidism.[ncbi.nlm.nih.gov ] Osteosclerosis , hypertrophic osteoarthropathy and periostitis
to pancytopenia and a “ dry tap ” on bone marrow aspirationleadsto pancytopenia and a “ dry tap ” on bone marrow aspiration
to extensive extramedullary haematopoiesisleadingto extensive extramedullary haematopoiesis
to failure of the bone marrow to produce blood cellsleadsto failure of the bone marrow to produce blood cells
MPN)-associated myelofibrosis(passive) are caused byMPN)-associated myelofibrosis
to anaemia and the presence of immature red and white blood cells in the circulationleadsto anaemia and the presence of immature red and white blood cells in the circulation
unique symptoms(passive) caused byunique symptoms
to severe anemia , weakness , fatigue and an enlarged spleen and liverleadsto severe anemia , weakness , fatigue and an enlarged spleen and liver
in marrow hypocellularity and extramedullary hematopoiesisresultingin marrow hypocellularity and extramedullary hematopoiesis
to an inability to aspirate marrow for assessmentleadsto an inability to aspirate marrow for assessment
increased perivascular pressure [ 11causingincreased perivascular pressure [ 11
a cancer(passive) caused bya cancer
from disseminated mycobacterial infection , autoimmune diseases , renal osteodystrophy , hypo or hyperthyroidism.[2can also resultfrom disseminated mycobacterial infection , autoimmune diseases , renal osteodystrophy , hypo or hyperthyroidism.[2
the aspiration of nucleated cellspreventsthe aspiration of nucleated cells
reasons(passive) caused byreasons
Monitor signs of anemia(passive) caused byMonitor signs of anemia
from an overproduction of collagen by marrow stromal cells as a consequence of abnormal concentrations of cytokines produced by tumor cells or inflammatory cells that control collagen metabolismresultsfrom an overproduction of collagen by marrow stromal cells as a consequence of abnormal concentrations of cytokines produced by tumor cells or inflammatory cells that control collagen metabolism
alsomay contributealso
to onset of leukemiacan ... leadto onset of leukemia
in pancytopenia * Malignancy – Acute myelogenous leukemia ( AMLresultingin pancytopenia * Malignancy – Acute myelogenous leukemia ( AML
difficulty in aspirating neoplastic cellsmay causedifficulty in aspirating neoplastic cells
to a reduced platelet count and poor platelet functionleadsto a reduced platelet count and poor platelet function
from an increased deposition of collagens , which are polypeptidesresultsfrom an increased deposition of collagens , which are polypeptides
from an increased deposition of various interstitial and basement membrane glycoproteins , including collagen typesresultsfrom an increased deposition of various interstitial and basement membrane glycoproteins , including collagen types
skeletal diseases(passive) caused byskeletal diseases
to cytopeniasleadingto cytopenias
Kidney - induced rickets causescausesKidney - induced rickets causes
of small lymphoid cellpredominantly composedof small lymphoid cell
early satiaty & abd discomfortcan causeearly satiaty & abd discomfort